Development Of Endovascular Stents With Proactive Biocompatibility
Funder
National Health and Medical Research Council
Funding Amount
$428,470.00
Summary
Metallic cardiovascular implants, such as stents, used in the treatment of heart disease are not compatible with blood. They cause inflammation at the site of implantation and increase the risk of blood clots forming. We have developed a unique method of binding bioactive protein layers to the surface of metal alloys, and shown a significant improvement in their compatibility. Stents coated using our technology stand to dramatically improve the treatment of cardiovascular disease.
Development Of A Novel Endovascular Therapy For Occlusive Peripheral Vascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$624,197.00
Summary
We aim to develop and assess a new medical device for the treatment of diseased arteries. The new device uses an angioplasty balloon coated with a new drug to open narrowed arteries and will enable the arteries to remain open for longer periods and with less likelihood of unwanted side effects from the procedure.
A Fully Implantable Self Powered Extra Aortic Counterpulsation Device? For Translational Development In Hypertensive Heart Failure
Funder
National Health and Medical Research Council
Funding Amount
$901,586.00
Summary
The development of a low cost self-powered cardiac aortic assist device to improve blood flow to the heart and rest of the body. The device is placed on the external surface of the large blood vessel (aorta) leaving the heart and provides gentle counterpulsation to improve blood flow. This aortic cardiac assist device is a therapeutic treatment for early stage heart failure.
Development Of A Catheter-based Device For The Detection Of Vulnerable Atherosclerotic Plaques
Funder
National Health and Medical Research Council
Funding Amount
$560,582.00
Summary
Atherosclerosis (hardening of blood vessels) is a major cause of disability and death worldwide. These lesions can suddenly become unstable leading to rupture and the occlusion of blood vessels with catastrophic complications such as heart attacks and strokes. Our project aims to develop a novel invasive imaging system to reliably detect these unstable lesions before they cause complications so that preventive measures can be taken, potentially saving many lives.