Fundamental study of fracture-controlled compensation grouting for ground movement. This project aims to investigate the fundamentals of fracture-controlled compensation grouting in various types of soil, so as to optimise the compensation efficiency and to minimise the risk of collapse of nearby structures. This will result in the minimisation of ground movements induced by underground excavations, which pose a major threat to existing infrastructure and communities worldwide. Small-scale labor ....Fundamental study of fracture-controlled compensation grouting for ground movement. This project aims to investigate the fundamentals of fracture-controlled compensation grouting in various types of soil, so as to optimise the compensation efficiency and to minimise the risk of collapse of nearby structures. This will result in the minimisation of ground movements induced by underground excavations, which pose a major threat to existing infrastructure and communities worldwide. Small-scale laboratory experiments, centrifuge tests and numerical analyses will be conducted to develop an effective and economical grouting method that will provide a valuable design tool for engineers.Read moreRead less
Frontiers in bone and joint regeneration. Key outcomes of this project will deliver innovative strategies for scaffold-based bone and cartilage engineering whilst contributing to the education of a new generation of bioengineers, biomaterial scientists and tissue engineers with a strong international profile.
Adaptive structural systems for high-performance buildings. This project aims to develop adaptive structural systems for high-performance buildings. A new theoretical platform will be instrumental in the development of building technologies such as adaptive shading and ventilation components. In a reversal of the conventional design avoidance of structural phenomena such as lateral and flexural-torsional buckling, these phenomena will be exploited to achieve functional forms for shading componen ....Adaptive structural systems for high-performance buildings. This project aims to develop adaptive structural systems for high-performance buildings. A new theoretical platform will be instrumental in the development of building technologies such as adaptive shading and ventilation components. In a reversal of the conventional design avoidance of structural phenomena such as lateral and flexural-torsional buckling, these phenomena will be exploited to achieve functional forms for shading components. Thin-metal ventilation ducts will be embedded within structural components to produce optimised ventilation strategies and to increase thermal mass, while accounting for their structural contribution.Read moreRead less
Modelling and simulation of complex granular flows. Granular flows are of crucial importance in a wide range of problems related to civil infrastructure. These include landslides and similar catastrophic events, often leading to loss of life and property. The project aims to develop new methods for accurate prediction of such events thus allowing for the formulation of efficient mitigation strategies.
Minimally invasive monitoring of sleep for disease management. Sleep, diet and exercise are the three pillars of wellbeing with poor sleep associated with medical issues such as obesity and congestive heart failure. This project will advance sleep analysis by researching new ways of monitoring that are highly accurate and convenient, enabling physicians to improve the monitoring of significant health issues.
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Hybrid Imaging System for Breast Cancer Detection. Due to the ever increasing number of breast cancer mortalities in Australia, there is an urgent need for an efficient and reliable diagnostic imaging system. This research utilises a novel method to build an imaging system, which is accurate and reliable in the early detection of tumours. The work of this fellowship will improve quality of life of Australian women and put us at the international forefront of research in medical imaging, enhancin ....Hybrid Imaging System for Breast Cancer Detection. Due to the ever increasing number of breast cancer mortalities in Australia, there is an urgent need for an efficient and reliable diagnostic imaging system. This research utilises a novel method to build an imaging system, which is accurate and reliable in the early detection of tumours. The work of this fellowship will improve quality of life of Australian women and put us at the international forefront of research in medical imaging, enhancing our already significant international presence in the area. The project will potentially lead to valuable intellectual property for commercialisation opportunities besides strengthening key international collaborations.Read moreRead less
Variational multiscale modelling of granular materials. Granular materials play an important role in a wide-range of problems related to physical infrastructure. These include landslides and similar catastrophic events often leading to loss of life and property. This project will aim to develop new methods for adequate simulation of granular flows to allow formulation of efficient risk mitigation strategies.
Harnessing the bioactivity of proteins and polypeptides: understanding and controlling adsorption processes to optimise linker free immobilisation. This project will use physical techniques and simulations to understand the interactions of biomolecules and plasma activated surfaces, allowing control of the biomolecule layer composition, orientation and conformation. This control, together with the ability of these surfaces to "lock-in" the optimised layer, will create a new generation of biodevi ....Harnessing the bioactivity of proteins and polypeptides: understanding and controlling adsorption processes to optimise linker free immobilisation. This project will use physical techniques and simulations to understand the interactions of biomolecules and plasma activated surfaces, allowing control of the biomolecule layer composition, orientation and conformation. This control, together with the ability of these surfaces to "lock-in" the optimised layer, will create a new generation of biodevices.Read moreRead less
Advanced biosensing in the terahertz (THz) sub-wavelength regime. This project will build on Australian excellence in photonics, exploiting the advanced use of T-rays for sensing of biological substances such as proteins and DNA. For the first time, this will enable contactless automated sensing for high-speed medical screening of diseases, a critical step toward the ultimate vision of customised medicine.