Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fu ....Engineering improved technology for nanoparticle-based adjuvant manufacture. Over the next decade nanotechnology will redefine vaccines for animal and human health. Nanoparticle adjuvants will boost engineered vaccines that use minimal antigens such as recombinant proteins and synthetic peptides. This project aims to develop a platform technology for making and controlling the properties of inulin nanoparticles by optimising the engineering and manufacturing aspects of inulin nanoparticles to fundamentally understand the relationship between physical-chemical properties and efficacy. Completion of this project aims to produce potent nanoparticle-based adjuvants underpinned by novel manufacturing technology, to ultimately facilitate the development of more effective and protective vaccines for animals and humans.Read moreRead less
Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microflu ....Platform technologies for multifunctional nanocarrier systems. Smart targeted nanocarriers offer new opportunities for drug delivery. This project aims to develop new platforms for reproducibly producing and screening targeted nanocarriers. The platform technologies developed in this project aim to revolutionise current strategies for designing and evaluating drug delivery systems, and will accelerate the clinical translation of targeted drug delivery. This will include a novel one-step microfluidic platform technology for reproducibly producing targeted polymer nanocarriers having systematically varied properties, a dual-templating method for making targeted silica nanocapsules and new design of in vivo-mimicking 'Tissue Chips' for screening and evaluating the nanocarriers.Read moreRead less
Solar-driven thermochemical dissociation of carbon dioxide and water to produce carbon-neutral fuels. The biggest challenge to humanity of the century is to develop enabling clean energy resources to encounter rapidly diminished fossil fuel and accelerated global warming conditions. This project will offer a solution by developing a unique solar-driven thermochemical system capable of cleaving carbon dioxide and water to produce artificial syngas.
Development of High Performance Nanostructured (Bi, Sb)2Te3 Nanomaterials. The direct energy conversion between heat and electricity, based on thermoelectric effects without moving parts, has been considered as a green and sustainable solution to the global energy dilemma. This project aims to develop novel band-engineered (Bi, Sb)2Te3 nanomaterials for high-efficiency energy conversion using novel microwave assisted wet chemistry approach, coupled with nanostructure and band engineering strateg ....Development of High Performance Nanostructured (Bi, Sb)2Te3 Nanomaterials. The direct energy conversion between heat and electricity, based on thermoelectric effects without moving parts, has been considered as a green and sustainable solution to the global energy dilemma. This project aims to develop novel band-engineered (Bi, Sb)2Te3 nanomaterials for high-efficiency energy conversion using novel microwave assisted wet chemistry approach, coupled with nanostructure and band engineering strategies. The key breakthrough is to design high performance (Bi, Sb)2Te3 thermoelectrics for satisfying the high efficiency solid-state devices. The expected outcomes will lead to an innovative technology that waste heat recovery and refrigeration, which will place Australia at the forefront of practical energy technologies.Read moreRead less
Mechanical advantage: biomimetic artificial muscles for micro-machines. This project will develop better ways to operate miniature machines by copying the way that muscle operates in Nature. The outcome will be important for portable devices like digital cameras that need small, efficient motors. The artificial muscles developed in this project may also be used in medical prosthetics and more agile robots.
Discovery Early Career Researcher Award - Grant ID: DE130101264
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Carbon nanotube-based supercapacitors: breaking the energy density limit. Novel electrodes will be nano-architectured by using ultralong single-walled carbon nanotube arrays and transition metal oxides to produce next-generation supercapacitors. The outcomes will lead to unprecedented energy densities in energy storage devices for sustainable future energy solutions.
Advanced glazing systems for solar energy harvesting and radiation control. Development of advanced energy-saving glass and glazings capable of generating electricity is expected to lead towards new products of significant commercial potential. The outcomes of this project undertaken by Edith Cowan University and Tropiglas will raise the energy efficiency of commercial buildings and vehicles to levels not possible with other technologies.
Exploration of highly regenerable boron-nitrogen based hydrides for hydrogen storage. The project will design and synthesise novel boron-nitrogen hydrides. It will employ material design strategies, such as new synthesis techniques, dopant destabilisation, and dehydrogenation catalysts to design and experimentally validate novel multicomponent hydride systems with high storage capacities (above 9 wt% under near-ambient conditions) and high reversibility. The outcomes of this project will make a ....Exploration of highly regenerable boron-nitrogen based hydrides for hydrogen storage. The project will design and synthesise novel boron-nitrogen hydrides. It will employ material design strategies, such as new synthesis techniques, dopant destabilisation, and dehydrogenation catalysts to design and experimentally validate novel multicomponent hydride systems with high storage capacities (above 9 wt% under near-ambient conditions) and high reversibility. The outcomes of this project will make a significant enhancement in the performance of solid state hydrogen storage materials and will deliver a viable storage technology for a range of fuel cell applications.Read moreRead less
Liquid-phase hydrogen carriers for energy storage and delivery. This project aims to overcome hydrogen storage and delivery issues by developing liquid-phase hydrogen storage materials with high hydrogen capacity, exceptional stability and that do not change phase during hydrogen evolution. This project will build on the recent synthesis of strategically important hydrogen storage compounds. The innovative liquid-phase hydrogen storage and delivery technology will enable effective usage of estab ....Liquid-phase hydrogen carriers for energy storage and delivery. This project aims to overcome hydrogen storage and delivery issues by developing liquid-phase hydrogen storage materials with high hydrogen capacity, exceptional stability and that do not change phase during hydrogen evolution. This project will build on the recent synthesis of strategically important hydrogen storage compounds. The innovative liquid-phase hydrogen storage and delivery technology will enable effective usage of established liquid fuel distribution techniques and infrastructure throughout the country. The project would benefit renewable energy, chemical, and manufacturing industries, where new employment opportunities would be created.Read moreRead less
Safe and efficient biomedical nanomaterials. This project aims to rationally engineer nanomaterials with controlled biological responses. Nanomaterials are becoming widespread in biomedicine and engineering, but are inefficient and unsafe. This project will develop atomic scale models to understand interactions between engineered nanoparticles and the crowded cellular environment. It will design extremely sensitive biosensors and theranostic nanodevices combining medical imaging capacity with pr ....Safe and efficient biomedical nanomaterials. This project aims to rationally engineer nanomaterials with controlled biological responses. Nanomaterials are becoming widespread in biomedicine and engineering, but are inefficient and unsafe. This project will develop atomic scale models to understand interactions between engineered nanoparticles and the crowded cellular environment. It will design extremely sensitive biosensors and theranostic nanodevices combining medical imaging capacity with precision targeted drug delivery to improve efficiency and safety of nanomaterials for biomedical applications in both vitro and in vivo enabling cost effective early diagnostics and more efficient treatments.Read moreRead less