Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100137
Funder
Australian Research Council
Funding Amount
$881,758.00
Summary
Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-fun ....Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-funded resource for integrated exposure research into the future. The archive is expected to support longitudinal and cross-sectional studies to assess trends in exposure to chemical and biological hazards in the Australian population, identify emerging hazards, and provide a scientific basis for policy and regulatory actions.Read moreRead less
Healing Country: integrating knowledge systems to meet climate challenges. Aboriginal and Torres Strait Islander communities are currently experiencing severe environmental challenges related to a changing climate. Led by Aboriginal communities, this project aims to integrate traditional knowledges and environmental and health data to create community story-data maps. These interactive, online maps will be a unique and powerful blend of information, providing a rich evidence base, decision-suppo ....Healing Country: integrating knowledge systems to meet climate challenges. Aboriginal and Torres Strait Islander communities are currently experiencing severe environmental challenges related to a changing climate. Led by Aboriginal communities, this project aims to integrate traditional knowledges and environmental and health data to create community story-data maps. These interactive, online maps will be a unique and powerful blend of information, providing a rich evidence base, decision-support and communication tool to inform the co-design of local climate change mitigation, adaptation and resilience plans. The project aims to give agency to Aboriginal communities in leading a systems change process to reduce environmental risks and strengthen health and wellbeing.Read moreRead less
The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess c ....Understanding Australia by analysing wastewater during the Census 2021 . This project aims to utilise the Australian Census 2021, a unique opportunity to link exposure to chemical and biological hazards with catchment socio-demographic data via systematic wastewater analysis. The project is expected to advance our capabilities to identify emerging hazards and understand factors that affect spatiotemporal trends in hazards across Australia. Moreover, in a world first, the project aims to assess chemical fate on a national level by linking sales/use with fate and release from wastewater treatment plants and assess treatment efficiency at >100 plants around Australia. The project expects to provide insight for government, wastewater managers and industry into hazards that may affect environmental and human health.Read moreRead less
Min/Max Autocorrelation Factors in Time Series Studies of the Adverse Health Effects of Ozone. The annual health costs associated with exposure to air pollution in Australia have been estimated at between $3 and 5.3 billion. Given these costs, it is vital to conduct research that ensures public health officials and policy makers stay fully informed of Australia’s air pollution problem. The project proposes to address this need by developing methodology to detect trends in air pollution concentra ....Min/Max Autocorrelation Factors in Time Series Studies of the Adverse Health Effects of Ozone. The annual health costs associated with exposure to air pollution in Australia have been estimated at between $3 and 5.3 billion. Given these costs, it is vital to conduct research that ensures public health officials and policy makers stay fully informed of Australia’s air pollution problem. The project proposes to address this need by developing methodology to detect trends in air pollution concentrations and reduce measurement error in recorded air pollution concentrations. This will enable relevant authorities to produce more accurate estimates of air pollution health costs and implement more appropriate pollution regulations and health warnings.Read moreRead less
Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alter ....Estimating use of tobacco and nicotine products through wastewater analysis. This project aims to equip the Australian public health and security sector with a tool to accurately measure tobacco consumption in the general population. Specific human biomarkers in urine will be identified using non-target approaches and their pharmacokinetics quantified. The new data will address critical gaps in our knowledge on the population-level excretion of biomarkers for the consumption of tobacco and alternative nicotine products. The outcomes of this project will provide reliable, cost-effective estimates of tobacco consumption for use with wastewater-based epidemiology assessments. This will enable changes in tobacco use to be accurately evaluated for the first time and improve the efficacy of tobacco control measures.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100032
Funder
Australian Research Council
Funding Amount
$240,000.00
Summary
Ultra-high-performance liquid chromatography ion trap mass spectrometer to develop new capabilities in environmental and human toxicology. This facility will be dedicated to developing methods and analyses of environmental contaminants and by-products that are currently not well understood. Having this analytical capability will underpin leading research in environmental toxicology and chemistry, and will help to minimise environmental and human exposure to harmful contaminants.
Investigation Of The Characteristics And Properties Of Mixed Function Oxidases (mfo) In Commercially Significant Fish From SA Waters And Assessment Of Their Induction As A Potential Early Warning And Hence Biomarker Of Organic Pollutant Linked Stress
Funder
Fisheries Research and Development Corporation
Funding Amount
$9,145.00
Summary
Objectives: 1. To adapt methods currently developed overseas and in Port Phillip Bay to South Australian commercial fish species to indicate pollutant linked stress in fish 2. To enourage the use of these methods (if acceptable) by the relevant authorities as part of a monitoring program
Air pollution: do modern statistical model selection techniques make the silent killer speak too loud? Air pollution is estimated to cause 2400 deaths annually in Australia with an associated cost to the community of $17.2 billion. The outcomes of this project will enable an improved understanding of the association between air pollution and mortality in Australia, thereby allowing government, public health authorities, and regulatory agencies to implement better air pollution standards and pro ....Air pollution: do modern statistical model selection techniques make the silent killer speak too loud? Air pollution is estimated to cause 2400 deaths annually in Australia with an associated cost to the community of $17.2 billion. The outcomes of this project will enable an improved understanding of the association between air pollution and mortality in Australia, thereby allowing government, public health authorities, and regulatory agencies to implement better air pollution standards and provide more informed advice to the public on the necessity of avoiding exposure to air pollutants. These two outcomes are particularly important given Australia's ageing population and the fact that the elderly are among those most susceptible to harm from air pollution exposure.Read moreRead less
Seagrass tolerance of oil spills - scaling of pollution impacts. Seagrasses provide vital ecosystem services (such as sediment stabilisation and habitat provision) in Australian coastal waters. The contribution of pollutants to current seagrass decline is poorly understood. The Australian shipping industry is the 5th largest in the world but there is very little data on the impacts of petroleum hydrocarbons on intertidal seagrasses and hence no information for coastal resource managers to use in ....Seagrass tolerance of oil spills - scaling of pollution impacts. Seagrasses provide vital ecosystem services (such as sediment stabilisation and habitat provision) in Australian coastal waters. The contribution of pollutants to current seagrass decline is poorly understood. The Australian shipping industry is the 5th largest in the world but there is very little data on the impacts of petroleum hydrocarbons on intertidal seagrasses and hence no information for coastal resource managers to use in decision-making in the event of an oil spill. This project will assess the relative toxicities of a number of petroleum hydrocarbons on Australian seagrass species to provide necessary data for the development of effective management practice.Read moreRead less