Footwear For Self-managing Knee Osteoarthritis Symptoms: The Footstep Trial
Funder
National Health and Medical Research Council
Funding Amount
$590,532.00
Summary
Self-management of symptoms is an important part of treatment for people with knee osteoarthritis. Footwear influences forces across the knee joint and it is unclear which types of shoes are best to minimise arthritis symptoms. This study will compare the effects of flat flexible shoes to stable supportive shoe styles on pain and physical function over 6 months in people with painful knee osteoarthritis.
Refining And Testing A Promising New Treatment For Chronic Pain.
Funder
National Health and Medical Research Council
Funding Amount
$743,947.00
Summary
Chronic pain costs Australia about 35 billion dollars a year. Recent scientific discoveries show that treatment aimed at correcting problems in how the brain processes sensory input can reduce pain and disability. This project will clarify some key aspects of these problems and use that information to make final adjustments to an already very promising treatment. We will then test the treatment in a definitive and comprehensive clinical trial.
CIVIC: A Randomised Trial Of A Low-cost, Community-based Model Of Care To Prevent Serious Complications And Premature Death After Spinal Cord Injury In Bangladesh
Funder
National Health and Medical Research Council
Funding Amount
$845,874.00
Summary
We will conduct a randomised controlled trial to determine the effectiveness and cost-effectiveness of a low-cost and sustainable community-based model of care for people who have returned home after spinal cord injury in Bangladesh. The model of care involves regular telephone-based monitoring and provision of ongoing education and advice with a limited home-based service. This package of care will be provided in the first two years following discharge from hospital.
Trauma-focused CBT & Exercise For Chronic Whiplash: Addressing All Aspects Of A Chronic Condition
Funder
National Health and Medical Research Council
Funding Amount
$673,562.00
Summary
Chronic pain following whiplash injury is common and incurs substantial personal and economic costs. There are few effective treatments available. Recent research has shown that many people with chronic whiplash also have symptoms of posttraumatic stress. This study will investigate whether combining an intervention aimed at decreasing posttraumatic stress with exercise will decrease pain and disability in people with chronic whiplash
COMPARE- Constraint Induced Or Multi-Modal Aphasia Rehabilitation: An RCT Of Therapy For Stroke Related Chronic Aphasia
Funder
National Health and Medical Research Council
Funding Amount
$1,035,668.00
Summary
COMPARE is a 3 arm national randomised controlled trial comparing two types of intensive speech pathology treatment to usual care, for people with language disability 6 months to 3 years following stroke. After stratification by aphasia severity, participants are randomised to Multi-modality Aphasia Therapy, Constraint Induced Aphasia Therapy, or usual care. Cognitive, language, and speech assessments at baseline will enable sophisticated predictors of treatment responsiveness to be defined.
Optimising Upper Limb Recovery Following Stroke: A Randomised Controlled Trial Of The Effects Of Botulinum Toxin-A Combined With Intensive Rehabilitation Compared To Botulinum Toxin-A Alone
Funder
National Health and Medical Research Council
Funding Amount
$1,070,230.00
Summary
The devastating loss of movement in the hand after stroke could potentially be addressed, but we currently lack of research investigating treatment interventions. This randomised controlled trial will compare the routine interventions of botulinum toxin to botulinum toxin plus best-practice therapy for both cost and clinical outcome. Findings from this trial will provide the necessary information to make decisions about what will improve spasticity and function in the hand and arm after stroke.
Affordable Technology To Improve Physical Activity Levels And Mobility Outcomes In Rehabilitation
Funder
National Health and Medical Research Council
Funding Amount
$1,465,653.00
Summary
Repetitive exercise is a crucial part of rehabilitation for people with impaired mobility but current exercise levels are insufficient for optimal outcomes. Affordable exercise-based video- and computer game technology could enable additional exercise for rehabilitation patients at a relatively low cost. We propose a randomised trial to establish the impact on physical activity and mobility of the addition of these technologies to usual care for people admitted to rehabilitation wards.
Circuit Class Therapy For Rehabilitation Clients. A Pragmatic Randomized Controlled Trial Of Therapy Intensity (CIRCIT).
Funder
National Health and Medical Research Council
Funding Amount
$526,361.00
Summary
Loss of independence is common after stroke, and may lead to reduced quality of life and admission to nursing home care. We will investigate if an increased amount of rehabilitation following stroke leads to improved mobility. Two ways of delivering more intense rehabilitation will be compared with usual care to find out which leads to improved physical mobility, and how they compare economically. This will allow health service providers to optimise services and will benefit people with stroke.
Arthritis of the big toe joint is a common and disabling problem in many Australians, but few effective treatments are available. This project will determine whether a combination of exercises and wearing a special shoe with a curved sole (a rocker-sole shoe) is more effective in treating this condition than exercises alone.
Safety And Efficacy Of A Surgically Implanted Suprachoroidal Retinal Prosthesis (Bionic Eye)
Funder
National Health and Medical Research Council
Funding Amount
$1,233,826.00
Summary
A bionic eye is a electronic device which can stimulate the remaining visual pathway in a person who is blind, to restore some basic vision. Our team have previously shown that our novel bionic eye device can be safely implanted in a patient, and can give improvements in vision when tested in a laboratory environment. The next stage of the research is to provide patients with a more advanced device, which will contain more electrodes and also be able to be taken home.