Practical strategies for engineering the CO2-fixing enzyme, Rubisco, whose subunits are encoded in different subcellular compartments. My recent replacement of the plant CO2-fixing enzyme, Rubisco, with a less efficient bacterial version, with a single type of subunit encoded by a single gene, demonstrated the feasibility of replacing Rubisco. This encourages ongoing attempts to replace plant Rubisco with more efficient versions that would allow the plants to grow with less water, fertiliser or ....Practical strategies for engineering the CO2-fixing enzyme, Rubisco, whose subunits are encoded in different subcellular compartments. My recent replacement of the plant CO2-fixing enzyme, Rubisco, with a less efficient bacterial version, with a single type of subunit encoded by a single gene, demonstrated the feasibility of replacing Rubisco. This encourages ongoing attempts to replace plant Rubisco with more efficient versions that would allow the plants to grow with less water, fertiliser or light. The most efficient Rubiscos are more complex, with two different types of subunits which, in plants, are encoded in different subcellular compartments (nucleus and plastid). This proposal addresses the challenges associated with complementary engineering both genomes to substitute foreign Rubiscos into higher-plant chloroplasts.Read moreRead less
Ethics, responsibility and the carbon budget. This project aims to provide a rigorous ethical framework for dividing the world’s remaining ‘carbon budget’ (CB). In order to avoid climate change the world must drastically limit its emissions of greenhouse gases. The project will develop a new analysis of how our assumptions concerning risk and harm shape conception of the CB. It will also provide a new understanding of how future emission rights should be allocated given that countries have emitt ....Ethics, responsibility and the carbon budget. This project aims to provide a rigorous ethical framework for dividing the world’s remaining ‘carbon budget’ (CB). In order to avoid climate change the world must drastically limit its emissions of greenhouse gases. The project will develop a new analysis of how our assumptions concerning risk and harm shape conception of the CB. It will also provide a new understanding of how future emission rights should be allocated given that countries have emitted vastly different quantities of greenhouse gases in the past. The project will analyse how the CB will impact the climate transition plans of countries such as Australia. The project will thus bring significant new research in philosophy to bear on a practical issue.Read moreRead less
Design and Synthesis of Photoactive Peptides Based on Photosynthetic Reaction Centres. The aim of this proposal is to generate new and useful electron transfer components for biotechnological applications. We plan to design and synthesize artificial photoactive peptides inspired from natural photosynthetic reaction centres which capture the energy of light and convert it into usable forms of chemical energy. Our research will provide the ground work for the development of light-driven oxidation- ....Design and Synthesis of Photoactive Peptides Based on Photosynthetic Reaction Centres. The aim of this proposal is to generate new and useful electron transfer components for biotechnological applications. We plan to design and synthesize artificial photoactive peptides inspired from natural photosynthetic reaction centres which capture the energy of light and convert it into usable forms of chemical energy. Our research will provide the ground work for the development of light-driven oxidation-reduction catalysts that can be used in the production of clean fuels and chemical products.Read moreRead less
Long range toxic metal pollution in Australia and the Southern Ocean. This project aims to investigate how environmental change and human activities since industrialisation have impacted toxic metal transport and deposition on the south coast of Australia, Tasmania and Southern Ocean islands. This project expects to fill gaps in understanding of the global mercury cycle using a state-of-the-art multidisciplinary methodology including the role of sea salt aerosols and hemispheric-scale wind patte ....Long range toxic metal pollution in Australia and the Southern Ocean. This project aims to investigate how environmental change and human activities since industrialisation have impacted toxic metal transport and deposition on the south coast of Australia, Tasmania and Southern Ocean islands. This project expects to fill gaps in understanding of the global mercury cycle using a state-of-the-art multidisciplinary methodology including the role of sea salt aerosols and hemispheric-scale wind patterns . Anticipated outcomes involve a novel palaeo-atmospheric model that can be applied in other parts of the world. This should provide significant benefits, such as science-based evidence to ratify the Minamata Convention on Mercury and guide new regulations to reduce environmental/health risks from metal pollution.
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Ecohydrological forecasting: the pivotal role of root-zone soil moisture. This project aims to overcome the scientific and technological challenges preventing soil water and vegetation forecasting at useful land management scales (eg. 25 m). The significance is in enabling an unprecedented hyperresolution modelling capability for Australia through the integration of new ecohydrological theory with a range of satellite observations. Outcomes include more accurate, spatially-detailed information o ....Ecohydrological forecasting: the pivotal role of root-zone soil moisture. This project aims to overcome the scientific and technological challenges preventing soil water and vegetation forecasting at useful land management scales (eg. 25 m). The significance is in enabling an unprecedented hyperresolution modelling capability for Australia through the integration of new ecohydrological theory with a range of satellite observations. Outcomes include more accurate, spatially-detailed information of current soil water amounts, and reliable forecasts of vegetation condition several months into the future. This will greatly enhance timely decision making and forward planning by farmers, fire agencies, and other land and water managers, with corresponding increases in productivity, sustainability and community safety.Read moreRead less
The LASE process - a new approach to cost effective thin solar cells. This project aims to develop a process to produce a new type of single
crystalline silicon solar cell. The cell is made on very thin slices of silicon that are detached from a conventional high quality silicon wafer. The wafer is gradually consumed as successive slices are harvested from it. Substantially less silicon is used in each solar cell, which allows significant cost reductions.
Ascorbate and glutathione integrate the control of grapevine development. This project aims to make a step-change in understanding how the growth of woody perennial crops is regulated. The study of herbaceous annual plants has established that the antioxidants, ascorbate and glutathione, are important in regulating every step of plant development. However, this cannot readily translate to perennial life cycles. This project will develop novel genetic tools in grapevine that enable functional stu ....Ascorbate and glutathione integrate the control of grapevine development. This project aims to make a step-change in understanding how the growth of woody perennial crops is regulated. The study of herbaceous annual plants has established that the antioxidants, ascorbate and glutathione, are important in regulating every step of plant development. However, this cannot readily translate to perennial life cycles. This project will develop novel genetic tools in grapevine that enable functional studies of these antioxidants in a perennial plant for the first time. It will investigate how ascorbate and glutathione regulate the development of grapevine, and how these functions integrate with hormone and energy metabolism. The outcomes will advance our ability to manage perennial crops in current and future climates.Read moreRead less
Assessing absolute sustainability of global cities. The project aims to create a quantitative modelling framework for assessing the absolute sustainability of cities by combining global multi-region input-output analysis with the 'safe and just space' concept for human development. The model will allow assessment of the full supply chain environmental and social impacts of urban economic activities against biophysical planetary limits as well as social foundation thresholds defined in the litera ....Assessing absolute sustainability of global cities. The project aims to create a quantitative modelling framework for assessing the absolute sustainability of cities by combining global multi-region input-output analysis with the 'safe and just space' concept for human development. The model will allow assessment of the full supply chain environmental and social impacts of urban economic activities against biophysical planetary limits as well as social foundation thresholds defined in the literature. The project will advance sustainability science methodology and will greatly benefit worldwide initiatives for urban sustainability. Case studies on Australian cities will assess where interventions can be most practically, realistically and effectively implemented.Read moreRead less
Identifying potential barriers to transplanting modified forms of the CO2-fixing enzyme, Rubisco, into plants. Improving the ability of crops to use water, light and fertiliser more efficiently would have economic benefits and ease the environmental impacts associated with agricultural practices. It is thought that such improvements can be made by enhancing the efficiency of the photosynthetic protein, Rubisco, which fixes most of the CO2 in the biosphere. The research proposed here uses unique ....Identifying potential barriers to transplanting modified forms of the CO2-fixing enzyme, Rubisco, into plants. Improving the ability of crops to use water, light and fertiliser more efficiently would have economic benefits and ease the environmental impacts associated with agricultural practices. It is thought that such improvements can be made by enhancing the efficiency of the photosynthetic protein, Rubisco, which fixes most of the CO2 in the biosphere. The research proposed here uses unique Rubisco transplantation capabilities that I have developed to improve our fundamental understanding of how Rubisco is processed and its activity regulated in plants. This will pave the way for our ongoing efforts to engineer and transplant more efficient Rubisco into crops.Read moreRead less
Understanding the Origin and Development of Extreme and Mega Bushfires. Extreme and megafires result in significant damage to property and infrastructure and are associated with large suppression costs. These events form when separate fires Merge. Their increase occurrence in recent seasons highlights the importance of developing tools and technologies that better predict extreme events to aid fire response and inform strategies for greater resilience. This project combines fire field experiment ....Understanding the Origin and Development of Extreme and Mega Bushfires. Extreme and megafires result in significant damage to property and infrastructure and are associated with large suppression costs. These events form when separate fires Merge. Their increase occurrence in recent seasons highlights the importance of developing tools and technologies that better predict extreme events to aid fire response and inform strategies for greater resilience. This project combines fire field experiments with computer modelling to determine factors driving extreme fire development, and develop new knowledge and models. These enable better prediction of active fires, enhance the knowledge base of fire managers for critical decision making and to improve risk modelling and mitigation planning for fire-prone communities.Read moreRead less