CRCT Of A Multidisciplinary, Team Building Intervention To Manage Fever, Sugar And Swallowing (FeSS) In Acute Stroke
Funder
National Health and Medical Research Council
Funding Amount
$405,450.00
Summary
The latest acute stroke guidelines and recommendations from Ausralia's National Stroke Unit Program endorse a prompt and evidence-based treatment for fever, blood sugar and swallowing in acute stroke. This Clustered Randomised Control Trial (CRCT) will develop and rigorously evaluate a standardised, multidisciplinary team-building intervention for the management of fever, blood sugar and swallowing in patients following acute stroke. The intervention comprises: an evidence-based clinical treatme ....The latest acute stroke guidelines and recommendations from Ausralia's National Stroke Unit Program endorse a prompt and evidence-based treatment for fever, blood sugar and swallowing in acute stroke. This Clustered Randomised Control Trial (CRCT) will develop and rigorously evaluate a standardised, multidisciplinary team-building intervention for the management of fever, blood sugar and swallowing in patients following acute stroke. The intervention comprises: an evidence-based clinical treatment pathway (the FeSS Pathway) and facility-based support consisting of multidisciplinary, team building workshops, a standardised, interactive education program and engagement of local staff through support and feedback. Stroke Units allocated to the control group will receive only the FeSS Pathway with no facility-based support. Expected patient outcomes comprise decreased: disability on discharge, length of stay, 90-day disability, 90-day dependency, 90-day death and disability and higher 90-day health status for those patients allocated to receive care at intervention Stroke Units. Further, medical record audits will be undertaken to measure the integrity of the FeSS Pathway uptake. By conducting a CRCT, we will generate Level 2 evidence for the effectiveness of a standardised, multidisciplinary team-building intervention for the management of fever, blood sugar and swallowing in patients following acute stroke. Thus, this trial is highly significant both within Australia and internationally.Read moreRead less
Methodological Research In Meta-analysis And Evidence Synthesis: An Evidence-based Methods Approach
Funder
National Health and Medical Research Council
Funding Amount
$431,000.00
Summary
Systematic reviews synthesize available research to determine whether policy, health service delivery, public health, and clinical interventions are effective. Statistical methods underpin the validity of the findings in systematic reviews. This research will evaluate and develop statistical methods for systematic reviews with the aim of improving the quality of reviews and ensuring healthcare decisions are based on reliable research syntheses.
Increasing Value, Reducing Waste From Incomplete Or Unusable Reports Of Medical Research
Funder
National Health and Medical Research Council
Funding Amount
$788,486.00
Summary
We estimated that the avoidable waste in research - from design flaws, non-publication, and inadequate reporting - results in over $85 Billion annual loss. I will research innovations to reduce this waste. My focus is particularly on non-drug interventions - exercises, dietary changes, self-monitoring, e-health applications – which are often effective but more difficult to use in clinical practice, and being compiled in my recently founded Handbook of Non-Drug Interventions (see RACGP website).
Testing, Translation And Uptake Of Evidence In General Practice: A Systems Approach To Rapid Translation
Funder
National Health and Medical Research Council
Funding Amount
$2,411,050.00
Summary
Testing, Translation & Uptake of Evidence in General Practice: A systems approach. Though General Practice is the frontline of Australia’s health system, new research findings are often ignored by busy GPs, resulting in suboptimal care. We plan to improve this by: A. A network of influential GPs practices to test new research, B. Practice support units who provide GP and patient summaries of new research, C. Active transfer of successful new practices via social media, guidelines, and courses.
Australia & New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network
Funder
National Health and Medical Research Council
Funding Amount
$2,497,654.00
Summary
Arthritis and musculoskeletal conditions place an immense and growing burden on the world’s population. They affect 28% of Australians (>6.1 million people). With the support of CRE funding, the Australia and New Zealand Musculoskeletal (ANZMUSC) Clinical Trials Network will optimise musculoskeletal health through high quality, collaborative clinical research, building research capacity and effective transfer of research outcomes into clinical practice and health policy.
Reconceptualising Health Promotion: The Role Of Values, Ethics And Evidence In Obesity Intervention.
Funder
National Health and Medical Research Council
Funding Amount
$485,103.00
Summary
Obesity and overweight are public health priorities. Population-level programs, campaigns and regulations are required to prevent and reduce obesity. How should these interventions proceed? What is effective? What is ethical? How can we avoid doing harm? At present, we do not know. By studying current interventions in detail, and working with experts and practitioners in health promotion and ethics, this project will develop a new framework to guide overweight and obesity intervention in future.
Therapeutics For Repair And Regeneration Of The Cornea
Funder
National Health and Medical Research Council
Funding Amount
$166,087.00
Summary
Corneal disease is the commonest cause of irreversible blindness and of the 50 million people world-wide who are bilaterally blind, 10 million are blind from corneal involvement. This proposal will address corneal disease by 1. innovative translational research for corneal repair and regeneration; 2. developing evidence-based management guidelines for corneal disease, and 3. by optimising health service delivery.
A Roadmap For Aboriginal And Torres Strait Islander Adolescent Health: Defining Priority Health Needs And Actions Through The Empowerment & Capacity Development Of Young People.
Funder
National Health and Medical Research Council
Funding Amount
$2,002,448.00
Summary
A third of the Indigenous population are adolescents, their health central to cultural continuity and health equity. Yet priority health needs and evidence-based responses for Indigenous adolescents remain poorly defined, a barrier to effective policy. The project is significant because it will establish a roadmap to guide actions around Indigenous adolescent health. It will also result in a network of engaged and up-skilled Indigenous young people who can drive implementation.