Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity ....Evolution of halophytes: a phyloinformatic approach to understanding and exploiting the traits underlying salt-tolerance in plants. Salinity is an increasing burden on the Australian economy & environment, with >2 million ha of salt-affected land, at an annual cost to agriculture over $187 million. One solution is to exploit naturally salt-tolerant plants to increase productive agricultural land and restore salt-affected environments. To do this, we must increase basic knowledge of the diversity & distribution of salt-tolerance. This project is the first to use DNA sequences from thousands of species to understand the evolution of salt-tolerance in order to provide the foundation for the development of new crop varieties, selection of species that can be developed for bioremediation, and identification of traits that will be profitable targets for breeding programs. Read moreRead less
Mesozoic Austral Biodiversity: Research and Regional Museum Applications. The impact of environmental alteration on Australia’s biodiversity has poorly understood long-term effects. This project examines the controversial biogeography and evolution of Australia’s biodiversity during the Age of Dinosaurs (mid-Cretaceous ~100 MYA) and their adaptational responses to climatic change. Fossils readily capture the public imagination and thus help promote complex scientific concepts in the global media ....Mesozoic Austral Biodiversity: Research and Regional Museum Applications. The impact of environmental alteration on Australia’s biodiversity has poorly understood long-term effects. This project examines the controversial biogeography and evolution of Australia’s biodiversity during the Age of Dinosaurs (mid-Cretaceous ~100 MYA) and their adaptational responses to climatic change. Fossils readily capture the public imagination and thus help promote complex scientific concepts in the global media. This project raises awareness about sustainable use of non-renewable fossil resources through public education and ecotourism fieldwork programs; these will help generate local interest and thus protection of sensitive fossil localities by highlighting them as lucrative tourism assets for regional communities.Read moreRead less
Connectivity and movements of large pelagic species of ecotourism value. The project aims to answer key questions about the biology, ecology and sustainability of the world’s manta ray species to provide the information and tools for management and conservation of these charismatic and valuable species. In particular, the project aims to determine the likely impact of climate variability and fisheries that operate to Australia’s north on manta-based ecotourism in the Indo-Pacific region, as clim ....Connectivity and movements of large pelagic species of ecotourism value. The project aims to answer key questions about the biology, ecology and sustainability of the world’s manta ray species to provide the information and tools for management and conservation of these charismatic and valuable species. In particular, the project aims to determine the likely impact of climate variability and fisheries that operate to Australia’s north on manta-based ecotourism in the Indo-Pacific region, as climate change and active low-value fisheries may both jeopardise a high-value ecotourism industry. The project seeks to explore geographic distributions, local and large-scale movements, population sizes, structure, and inter-connectivity in the region to assess the effect of climate and fisheries on manta ray populations.Read moreRead less
E. coli as an indicator of faecal contamination in the Australian context. The goal of this research is to improve our ability to use Escherichia coli as an indicator of water quality by determining the extent to which non-faecal sources of E. coli contribute to coliform counts and to develop a method to differentiate non-faecal E. coli from those that are faecal derived.
Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmen ....Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmental and phenotypic datasets for snapper populations from across vast coastal regions of the two countries. The outcomes should substantially enhance intra- and inter-jurisdictional fisheries management and aquaculture initiatives, providing commercial, social and environmental benefits for many stakeholders.Read moreRead less
New modulators of voltage-gated sodium channel subtypes from Australian Tarantula venoms. The venoms of Australian tarantula spiders provide a unique and untapped source of bioactive molecules. From a large stock of venom, and in collaboration with Australian pharmaceutical company Xenome, we will develop a comprehensive library of venom components suitable for drug screening. Potential national benefits from this work include a huge reduction in the healthcare bill deriving from a new treatmen ....New modulators of voltage-gated sodium channel subtypes from Australian Tarantula venoms. The venoms of Australian tarantula spiders provide a unique and untapped source of bioactive molecules. From a large stock of venom, and in collaboration with Australian pharmaceutical company Xenome, we will develop a comprehensive library of venom components suitable for drug screening. Potential national benefits from this work include a huge reduction in the healthcare bill deriving from a new treatment for pain, as well as substantial royalty returns from drugs sales. Discoveries from the program are also likely to lead to an enhancement in Australia's reputation in the neurosciences and to the development of new diagnostic research tools. The major community benefit will be a reduction in the suffering of chronic pain patients.Read moreRead less
Development of technologies to monitor multimolecular complexes. Development of technologies to monitor multimolecular complexes. This project aims to develop technologies to monitor how proteins and their interacting molecules (such as hormones) form multi-component complexes, and how these complexes function in the cell, including movement from the cell surface, into different cellular compartments and back up to the surface. These technologies are expected to enable monitoring in live cells i ....Development of technologies to monitor multimolecular complexes. Development of technologies to monitor multimolecular complexes. This project aims to develop technologies to monitor how proteins and their interacting molecules (such as hormones) form multi-component complexes, and how these complexes function in the cell, including movement from the cell surface, into different cellular compartments and back up to the surface. These technologies are expected to enable monitoring in live cells in real-time with high sensitivity. This project could have broad benefits for and affect study of all aspects of the life sciences at the cellular and molecular levels. How these protein complexes function in cells underpins much of our understanding of biology, and technological tools.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
A Socially Conscious Smart IoT Platform for Water Quality Monitoring. This project will develop an intelligent remote water quality monitoring platform based on a new sensor network architectural paradigm. Expected outcomes include an artificially intelligent water quality monitoring system that is produced via a unique social enterprise business model. This approach will facilitate widespread remote water quality monitoring, leading to an enhanced understanding of the environment, whilst provid ....A Socially Conscious Smart IoT Platform for Water Quality Monitoring. This project will develop an intelligent remote water quality monitoring platform based on a new sensor network architectural paradigm. Expected outcomes include an artificially intelligent water quality monitoring system that is produced via a unique social enterprise business model. This approach will facilitate widespread remote water quality monitoring, leading to an enhanced understanding of the environment, whilst providing valuable training/education for the community stakeholders involved in the production of the system. The research outcome will be globally significant, enabling end users to meet key water quality objectives over time, and considerably increase productivity in the Australian agriculture/aquaculture industries.Read moreRead less
A stitch in time: evidence-based strategy to keep platypus from extinction. This project aims to assess the status of the iconic platypus, identified as ‘near-threatened’ in 2014. The project’s multidisciplinary approach plans to compare regulated and unregulated rivers to investigate metapopulation structure (via physical and genetic tagging), current condition and future adaptability of the species, as well as other threats and habitat quality. The project also links vulnerability of platypus ....A stitch in time: evidence-based strategy to keep platypus from extinction. This project aims to assess the status of the iconic platypus, identified as ‘near-threatened’ in 2014. The project’s multidisciplinary approach plans to compare regulated and unregulated rivers to investigate metapopulation structure (via physical and genetic tagging), current condition and future adaptability of the species, as well as other threats and habitat quality. The project also links vulnerability of platypus populations to conservation actions that reduce extinction risk, through rigorous decision analyses. It is anticipated that the project will deliver implementable conservation actions at relevant scales.Read moreRead less