Developing biogeographic know-how: Improving species divergence and dispersal estimations to examine geological and climatic evolutionary drivers. Anthropogenic activity over the last 150 years is now dramatically changing our global climate and ecosystems. The impact on biodiversity is already evident, and large-scale floral and faunal extinctions are predicted. This study unites a cohort of international experts in an interdisciplinary team to develop new molecular and mathematical methods to ....Developing biogeographic know-how: Improving species divergence and dispersal estimations to examine geological and climatic evolutionary drivers. Anthropogenic activity over the last 150 years is now dramatically changing our global climate and ecosystems. The impact on biodiversity is already evident, and large-scale floral and faunal extinctions are predicted. This study unites a cohort of international experts in an interdisciplinary team to develop new molecular and mathematical methods to expand our fundamental knowledge on how geological and global climate change have affected our world's species components and ecosystems in the past. This research is of environmental significance and global importance as it will improve our ability to predict how species behave under future predicted climate scenarios.Read moreRead less
Illuminating the evolutionary history of Australia’s most iconic animals. This project aims to pinpoint the nature and timing of key steps in macropod history and to test how these link with major climatic and biotic changes. Macropods (kangaroos and relatives) are widely considered the marsupial equivalents to hoofed mammals on other continents, but we have a weaker understanding of how their evolution was shaped by environmental change. This project will combine palaeontology, anatomy and gene ....Illuminating the evolutionary history of Australia’s most iconic animals. This project aims to pinpoint the nature and timing of key steps in macropod history and to test how these link with major climatic and biotic changes. Macropods (kangaroos and relatives) are widely considered the marsupial equivalents to hoofed mammals on other continents, but we have a weaker understanding of how their evolution was shaped by environmental change. This project will combine palaeontology, anatomy and genetics to address questions such as how and why ancestral macropods descended from the trees and evolved bipedal hopping, and the upper size limits of the kangaroo “body plan”. This should improve our understanding of the long-term effects of climate change on marsupials, and provide a test of key placental-based evolutionary models.Read moreRead less
Is New Guinea the missing link for understanding Australia’s rainforests? This project aims to understand the extent to which the animals in Australia have shared histories with animals from the islands of Melanesia, and especially New Guinea. Key outcomes will be identification of hotspots of unique and high evolutionary diversity across both regions, and understanding of whether New Guinea has been an overall refuge or source for rainforest animals as Australia became more arid over the last 2 ....Is New Guinea the missing link for understanding Australia’s rainforests? This project aims to understand the extent to which the animals in Australia have shared histories with animals from the islands of Melanesia, and especially New Guinea. Key outcomes will be identification of hotspots of unique and high evolutionary diversity across both regions, and understanding of whether New Guinea has been an overall refuge or source for rainforest animals as Australia became more arid over the last 20 million years. Expected benefits include addressing fundamental gaps in our knowledge of the history of both the Australian continent and its resident biota such as when landbridges first formed with New Guinea, and the identification of priority areas for conservation investment in both Australian and Melanesia.Read moreRead less
A molecular/morphological view of animal evolution based on marsupials. This project aims to provide high-accuracy methods of evolutionary inference extendable to nearly all other organisms. It aims to research the evolution of animal diversity and calibrate evolutionary timescales on a case study of marsupial mammals, and differentiate between internal and external factors that govern animals’ ability to adapt and diversify. The project will collate a large, open-source three-dimensional catalo ....A molecular/morphological view of animal evolution based on marsupials. This project aims to provide high-accuracy methods of evolutionary inference extendable to nearly all other organisms. It aims to research the evolution of animal diversity and calibrate evolutionary timescales on a case study of marsupial mammals, and differentiate between internal and external factors that govern animals’ ability to adapt and diversify. The project will collate a large, open-source three-dimensional catalogue of the evolving marsupial skeleton, which could provide a detailed and publicly accessible narrative of the evolutionary past and future adaptability of Australian marsupials. The proposed development of methods to quantify the effect of past and present biodiversity crises (e.g. environmental change) is expected to inform longer-term conservation planning.Read moreRead less
Diversification and conservation of Australian frogs. Australia's 216 known species of frogs are exceptionally diverse, 98 per cent are found nowhere else in the world and many of them are in trouble. This project will test ideas concerning the tempo of Australian frog diversification, identify previously cryptic new species and provide information critical to the conservation of Australia's declining frogs.
Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations t ....Protecting cereal grain development at high temperatures. This project aims to investigate new temperature-responsive factors that regulate cereal grain development to protect grain production under heat stress. The new research will leverage international collaborations with access to cutting-edge genetic and technological resources, and refine novel X-ray imaging techniques in Australia, to observe how temperature affects flower structure and function in barley and rice. Favourable mutations that optimise plant yield and fitness will be defined and explored in other, more complex, cereals such as wheat. Expected outcomes will be fundamental breakthroughs in understanding how plants respond to, and buffer, the effects of heat to lead to translational breeding strategies that bolster grain yield.Read moreRead less
Rediscovering Aboriginal dispersal pathways. This project aims to use cutting-edge and transdisciplinary tools in partnership with Aboriginal people to rediscover deliberate prehistoric plant dispersal pathways along the Australian east coast. By working on three unrelated species with similar disjunct distributions, expected outcomes include detecting significant ‘cultural’ vegetation patterns that will challenge current assumptions about 'natural' plant distributions. New associations between ....Rediscovering Aboriginal dispersal pathways. This project aims to use cutting-edge and transdisciplinary tools in partnership with Aboriginal people to rediscover deliberate prehistoric plant dispersal pathways along the Australian east coast. By working on three unrelated species with similar disjunct distributions, expected outcomes include detecting significant ‘cultural’ vegetation patterns that will challenge current assumptions about 'natural' plant distributions. New associations between plant biogeography and deliberate Aboriginal manipulation of Australian environments will benefit cultural heritage, land management and restoration initiatives.Read moreRead less
Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understan ....Investigating differences in decision-making ability in older adults. This project aims to investigate how healthy ageing impacts decision making and its associated neural circuits using computation modelling and neurogenetic methods. Decision-making is a fundamental cognitive ability, allowing us to choose the best course of action. This project will investigate the relationship between genes and decision-making performance across the adult lifespan. Expected outcomes include a deeper understanding of how decision-making evolves in healthy ageing, and a tool based on genetic scores and computational modelling to predict an individual's trajectory of cognitive function. This could help identify individuals who are at risk for cognitive decline, which could then inform better interventions.Read moreRead less
Contemporary and retrospective genomic analyses of tiger and white sharks. This project aims to elucidate population structure and spatiotemporal changes in population distribution of tiger and white sharks; estimate the effective number of individuals across populations; and investigate signatures of adaptive evolution in tiger- and white shark populations in response to exploitation and global change. It will perform high-resolution retrospective genomic analyses using DNA extracted from conte ....Contemporary and retrospective genomic analyses of tiger and white sharks. This project aims to elucidate population structure and spatiotemporal changes in population distribution of tiger and white sharks; estimate the effective number of individuals across populations; and investigate signatures of adaptive evolution in tiger- and white shark populations in response to exploitation and global change. It will perform high-resolution retrospective genomic analyses using DNA extracted from contemporary and archival tiger and white shark skeletal material held in museum and trophy collections around the world. This project expects to gain valuable insight into the biology of both species and provide information for conservation and management purposes.Read moreRead less
Unravelling the principles of bilateral brain wiring. This project seeks to investigate the molecular principles of brain wiring in mammals and how small changes can generate complex outcomes. Neurons in the mammalian brain must be precisely wired together for the brain to function correctly. The project aims to identify the molecular and cellular rules governing commissural wiring in the mammalian cortex to determine how the largest fibre tract in the human brain, the corpus callosum, evolved. ....Unravelling the principles of bilateral brain wiring. This project seeks to investigate the molecular principles of brain wiring in mammals and how small changes can generate complex outcomes. Neurons in the mammalian brain must be precisely wired together for the brain to function correctly. The project aims to identify the molecular and cellular rules governing commissural wiring in the mammalian cortex to determine how the largest fibre tract in the human brain, the corpus callosum, evolved. This may have involved modifications in mechanisms affecting axon guidance that differ between placentals and marsupials. The project investigates the regulatory gene networks determining commissural neuron fate, the regulation of axon guidance components, and the influence of surrounding brain tissue on the development of commissural connections.Read moreRead less