Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise ....Femoral microarchitecture, strength and locomotion in adult people. This project aims at unravelling the load bearing capacity of human femora microarchitecture. The project will quantify the relationship between geometry, microarchitecture, strain and strength in adult people during normal and accidental motor tasks using micro-computed-tomography images, motion data, supercomputing technology and multivariate statistic. It will benefit the design of novel implantable devices, enhance exercise therapies and diagnostic techniques for promoting hip strength. The project will contribute to the engineering of biological tissue and the development of high-strength and light-weight bio-inspired materials.Read moreRead less
Social Impact and Connection Outcomes Associated with Community Sport. Outcomes of social connection from community sport are widely touted and supported to exist. However, we know little about how social infrastructure actually delivers these benefits. It is difficult to understand and develop practices that organisations can use to maximise the outcomes of sport participation. This research aims to investigate how social infrastructure delivers social connection outcomes associated with commun ....Social Impact and Connection Outcomes Associated with Community Sport. Outcomes of social connection from community sport are widely touted and supported to exist. However, we know little about how social infrastructure actually delivers these benefits. It is difficult to understand and develop practices that organisations can use to maximise the outcomes of sport participation. This research aims to investigate how social infrastructure delivers social connection outcomes associated with community sport. Expected outcomes include novel practice based tools and guidance for community groups to enhance social connection outcomes and new understanding about the role of social infrastructure in enhancing community connection. Improved social connection is expected to improve resilience and community wellbeing.
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Transitioning from out-of-home care: a longitudinal population-based study. This project aims to use a population-based method to examine the pathways of young people in, and transitioning from, out-of-home care in Western Australia. Young people in, and transitioning out of, out-of-home care experience many challenges. Care leavers, including a disproportionate number of Aboriginal young people, experience adverse outcomes across a range of domains leading to high social and economic costs for ....Transitioning from out-of-home care: a longitudinal population-based study. This project aims to use a population-based method to examine the pathways of young people in, and transitioning from, out-of-home care in Western Australia. Young people in, and transitioning out of, out-of-home care experience many challenges. Care leavers, including a disproportionate number of Aboriginal young people, experience adverse outcomes across a range of domains leading to high social and economic costs for the Australian community. The findings from the population-based data, together with an in-depth understanding of their lived experiences will identify a best practice model for improving their transition from care experiences to facilitate improved outcomes.Read moreRead less
Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australi ....Managing and mitigating social risks of major infrastructure projects. This project aims to reduce social risks of major infrastructure projects by generating an evidence-based social risk management framework. It brings together leading ANU researchers with top organisations in Australia's infrastructure sector, already working together via the ANU Institute for Infrastructure in Society. The project seeks to improve social risk management in a multi-billion dollar sector, vital to all Australians. The project is significant because it adopts a sector-wide view to systematically define social risk, co-create a social risk management framework and implement it via a new social risk management toolkit. This should lessen harm to communities, reduce delays and costs and benefit national infrastructure delivery.Read moreRead less
Novel link between bacterial sugar metabolism and cell-to-cell signalling. This project aims to understand the role and function of the bacterial communication system that enables bacteria to form complex communities and alter phenotypic traits, essential for survival in their environment. Bacteria survive in their environmental niches by developing complex multicellular communities. Cell to cell communication, termed quorum sensing (QS), is critical for this process and is linked to their capac ....Novel link between bacterial sugar metabolism and cell-to-cell signalling. This project aims to understand the role and function of the bacterial communication system that enables bacteria to form complex communities and alter phenotypic traits, essential for survival in their environment. Bacteria survive in their environmental niches by developing complex multicellular communities. Cell to cell communication, termed quorum sensing (QS), is critical for this process and is linked to their capacity to detect and secrete small signalling molecules, autoinducers. This project will provide a new paradigm in bacterial adaptation through comprehensive characterisation of the Autoinducer-2 QS system. This knowledge will provide future opportunities for intervention in microbial infestation with broad potential benefits.Read moreRead less
Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of dri ....Thermodynamics inversion for mineral systems. This project aims to provide a newly developed science approach to the Australian Lithospheric Architecture Magnetotelluric Project (AusLAMP). AusLAMP provides unparalleled geophysical information aimed at unravelling the tectonic history of the Australian continent and its mineral potential. The project will use thermodynamically based geodynamic simulators to jointly analyse and quantify intraplate deformation. This will illuminate the cause of driving fluid flow thorough the lithosphere, mineralisation phenomena, their datasets and geometries, and dynamic aspects of the processes driving mineral systems.Read moreRead less
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Organic Bioelectronics: Solving Key Barriers to Precision Neuromodulation. This project aims to combine the principles of molecular electronics and neurobiology to create organic conductors with enhanced biocompatibility that enable optical neuromodulation. This project expects to generate new knowledge regarding the properties of materials that promote connectivity with neurons and the ability of new microscopy tools to visualise this bio-interface. The expected outcome of this project includes ....Organic Bioelectronics: Solving Key Barriers to Precision Neuromodulation. This project aims to combine the principles of molecular electronics and neurobiology to create organic conductors with enhanced biocompatibility that enable optical neuromodulation. This project expects to generate new knowledge regarding the properties of materials that promote connectivity with neurons and the ability of new microscopy tools to visualise this bio-interface. The expected outcome of this project includes new high performing materials, measurement tools and fabrication approaches to overcome the key challenges to precision neuromodulation. A significant benefit of the new materials is their printability, providing the opportunity to establish a sovereign capability to manufacture low-cost bioelectronic systems in Australia.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE230100324
Funder
Australian Research Council
Funding Amount
$394,318.00
Summary
Cooperative Single Atom Catalysts for Zn-CO2 Batteries. This project aims to develop cooperative single-atom catalysts for efficient and selective electrocatalytic CO2 conversion and Zn-CO2 batteries. Cooperative catalysts at the single atom limit can potentially achieve enhanced electrochemical properties beyond state-of-the-art and will trigger significant theoretical and technological interests in energy conversion and storage fields. It is expected to generate new knowledge in materials scie ....Cooperative Single Atom Catalysts for Zn-CO2 Batteries. This project aims to develop cooperative single-atom catalysts for efficient and selective electrocatalytic CO2 conversion and Zn-CO2 batteries. Cooperative catalysts at the single atom limit can potentially achieve enhanced electrochemical properties beyond state-of-the-art and will trigger significant theoretical and technological interests in energy conversion and storage fields. It is expected to generate new knowledge in materials science and electrochemistry, using interdisciplinary approaches of atom-precise material engineering, in situ characterisation and full-cell optimisation. Significant economic and environmental benefits are expected from developing carbon-neutral CO2 electrolysers with low cost and high energy efficiency.Read moreRead less
A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of ....A Novel Geometric Approach to Shocks in Reaction-Nonlinear Diffusion Models. Reaction-nonlinear diffusion models play a vital role in the study of cell migration and population dynamics. However, the presence of aggregation, or backward diffusion, leads to the formation of shock waves - distinct, sharp interfaces between different populations of densities of cells - and the breakdown of the model. This project will develop new geometric methods to explain the formation and temporal evolution of these shock waves, while simultaneously unifying existing regularisation techniques under a single, geometric banner. It will devise innovative tools in singular perturbation theory and stability analysis that will identify key parameters in the creation of shock waves, as well as their dynamic behaviour.Read moreRead less