Mechanisms Underlying Adaptation To Reactive Balance Training For Falls Prevention
Funder
National Health and Medical Research Council
Funding Amount
$83,832.00
Summary
Reactive balance training using unpredictable trips and slips can reduce fall rates in older people by 60%, a significant improvement on current interventions. This project will determine the optimal dose to and physiological adaptations underlying reactive balance training. It will also determine how older people with a high fall risk benefit by this training. This study has the potential to enhance clinical practice and assist older people in maintaining independence and quality of life.
Feasibility, Safety, Adherence, And Efficacy For High Intensity Interval Training In A Hospital-Initiated Rehabilitation Program For Heart Disease
Funder
National Health and Medical Research Council
Funding Amount
$75,779.00
Summary
This project aims to investigate if high intensity interval training can be successfully integrated into a hospital-based cardiac rehabilitation program as a practical and safe alternative to the usual care exercise protocol (moderate intensity continuous training). We expect high intensity interval training will be a safe and practical option for appropriate patients, and will offer greater improvements in fitness, exercise adherence, cardiovascular risk factors, and intra-abdominal fat.
Defining The Benefits Of Exercise Training In Interstitial Lung Disease
Funder
National Health and Medical Research Council
Funding Amount
$94,250.00
Summary
The interstitial lung diseases (ILDs) are characterised by shortness of breath, progressive deterioration in exercise tolerance, poor quality of life and reduced life expectancy. Exercise training (ET) is one of few treatments to improve symptoms and QoL in ILD. However the response to ET was variable and dependent on disease type and severity. The aim of this study is to establish the effect of ET in ILD and to identify whether there is optimal timing for maximal benefit to be obtained.
Physical Activity In Community Dwelling People With Chronic Obstructive Pulmonary Disease
Funder
National Health and Medical Research Council
Funding Amount
$107,204.00
Summary
Chronic obstructive pulmonary disease is a serious lung condition causing severe breathlessness. Participation in a pulmonary rehabilitation program can reduce symptoms and improve quality of life but is unavailable to most people who only see their local doctor. These studies will look at the effect of a new home-based pulmonary rehabilitation program on how much physical activity people do and the best ways to measure exercise ability at home.
Through this project, I will determine how diet and physical activity can improve the health and quality of life of people suffering from chronic kidney disease. I will also assess whether lifestyle interventions have the potential to prevent chronic kidney disease. My results will directly impact the lives of people with kidney disease and could lead to public health interventions to prevent kidney disease.
The Haemodynamic Effects Of Cardiac Compression By Large Hiatal Hernia And The Relationship To Exercise Impairment.
Funder
National Health and Medical Research Council
Funding Amount
$117,270.00
Summary
Large hiatal herniae (HH) often cause debilitating exercise intolerance - the mechanism of which is unknown. This project will define the functional and haemodynamic significance of cardiac compression in patients with large HH, providing new insights into the mechanism of exercise impairment in these patients as well as clinical tools for pre-operative selection of patients likely to benefit most from surgical repair.
SMARTphone-Based Cardiovascular Risk Reduction In BREAST Cancer Patients
Funder
National Health and Medical Research Council
Funding Amount
$88,662.00
Summary
Heart disease is a leading cause of death in patients with breast cancer. Physical exercise during cancer treatment has been shown to improve overall survival by reducing future problems with the heart as well as recurrence of the cancer. Despite this, few women achieve the guideline recommended target for exercise. This study will test a Smartphone application called 'BreastMate' which is designed to promote physical activity and heart health in patients with breast cancer.
The Effect Of Moderate And High Intensity Exercise On Cardiovascular Health And Cardiac Remodelling
Funder
National Health and Medical Research Council
Funding Amount
$110,615.00
Summary
The interface between exercise, risk markers, atherosclerosis and cardiac function remains an understudied area of great public health importance. Our project will assess the effect of moderate and high intensity exercise on markers of cardiovascular disease (CVD) and cardiac remodelling.
Despite the clear epidemiological evidence that physical activity can reduce breast cancer recurrence and risk, little is know about the mechanisms. The aim of this project is determine the metabolic pathways and immunological effects of exercise in preclinical breast cancer models and in breast cancer patients, and to determine if there are synergistic effects with current systemic therapies.