SkyMapper and the Southern Sky Survey. The Southern Sky Survey is the first digital imaging survey of the entire southern hemisphere sky. The resulting information on a billion stellar and galaxy images underpins a number of significant national science programs of international prominence. These include the discovery of the oldest stars in our galaxy, fossils from its formation.
Novel techniques for statistical and mathematical analyses of sequence data. Algorithms will be developed for analysing and comparing the sequences of DNA letters and amino acids constantly being generated in massive quantities by biological research. The novel approach taken is based on the statistical frequency of occurrence of short words and is designed specifically for situations where current methods fail.
“Beacons in the Night” unveiling how galaxies light up dark matter. How dark matter influences the formation and evolution of galaxies is to this day an outstanding question in astrophysics. To answer it, world-class facilities and a unique combination of observations and theory are required. This DP team, a world-class team of observers and theorists, will tackle this question by leveraging on two multi-million dollar projects: the MAGPI galaxy survey and the hydrodynamical simulations suite EA ....“Beacons in the Night” unveiling how galaxies light up dark matter. How dark matter influences the formation and evolution of galaxies is to this day an outstanding question in astrophysics. To answer it, world-class facilities and a unique combination of observations and theory are required. This DP team, a world-class team of observers and theorists, will tackle this question by leveraging on two multi-million dollar projects: the MAGPI galaxy survey and the hydrodynamical simulations suite EAGLE-XL. MAGPI will deliver exquisite kinematics for hundreds of galaxies in the middle ages of the Universe, providing a view to the effect of dark matter on galaxies at this critical time, while EAGLE-XL represents the technological frontier in simulations and provides the best interpretative framework for MAGPI.Read moreRead less
Affective sensing technology for the detection and monitoring of depression and melancholia. This project will develop reliable and affective sensing technology and evaluate it as an objective measure of depressive disorders; a leading cause of disability worldwide. Outcomes will significantly support and aid clinicians in their diagnosis and treatment, thus providing a major breakthrough with significant research, healthcare and commercial possibilities.
Understanding the deep driving forces of Earth’s large-scale topography through time. We propose to model the convection of Earth’s mantle linked to tectonic plate motions to unravel their combined influence on the evolution of topography over 550 million years. The project will lead to an understanding of the driving forces of large-scale topography in continental interiors and along their margins through geological time.
Australian Laureate Fellowships - Grant ID: FL220100020
Funder
Australian Research Council
Funding Amount
$2,647,737.00
Summary
Unveiling the Winds of Star-Forming Galaxies. This project seeks to resolve an outstanding problem in the formation of cosmic structure: what is the nature of galactic winds, and what physical mechanisms are responsible for driving them? Answering these questions requires computer simulations of greater resolution than have previously been possible, coupled to next-generation telescopic observations. This research aims to develop novel methods to enable the required simulations, leveraging new h ....Unveiling the Winds of Star-Forming Galaxies. This project seeks to resolve an outstanding problem in the formation of cosmic structure: what is the nature of galactic winds, and what physical mechanisms are responsible for driving them? Answering these questions requires computer simulations of greater resolution than have previously been possible, coupled to next-generation telescopic observations. This research aims to develop novel methods to enable the required simulations, leveraging new hardware architectures at Australian supercomputer facilities, and to use these approaches to solve a major open problem in astrophysics, open new frontiers in simulation, and multiply the return on Australia's investment in both computer facilities and telescopes that will study galactic winds.Read moreRead less
RNA-binding proteins rewire transcriptomes in immune cell differentiation. This project aims to combine advanced computational and experimental techniques to investigate a new layer of gene regulation by novel RNA binding proteins (RBP) which control messenger RNA length in immune cells. This project expects to demonstrate that these RBPs have a profound effect on immune cell differentiation and response to infection. Expected outcomes include the discovery of new RBPs regulating immunity, with ....RNA-binding proteins rewire transcriptomes in immune cell differentiation. This project aims to combine advanced computational and experimental techniques to investigate a new layer of gene regulation by novel RNA binding proteins (RBP) which control messenger RNA length in immune cells. This project expects to demonstrate that these RBPs have a profound effect on immune cell differentiation and response to infection. Expected outcomes include the discovery of new RBPs regulating immunity, with mechanism and function determined by novel CRISPR editing of a transgenic mouse model. The significant benefit will be a more complete understanding of RNA mechanisms of immune response, which will be critical in informing future advances in the rapidly developing areas of RNA-based biotechnologies and synthetic immunology.Read moreRead less
Frontiers in inference about risk. The project aims to develop new methods for robust risk evaluation and minimisation under various constraints and scenarios. Risk evaluation, estimation and prediction using past data is a central activity in diverse areas such as finance, insurance, superannuation and environmental regulation. The project aims to propose and solve innovatively robust risk optimisation problems under constraints, taking into account the time dynamics. Applications include risk ....Frontiers in inference about risk. The project aims to develop new methods for robust risk evaluation and minimisation under various constraints and scenarios. Risk evaluation, estimation and prediction using past data is a central activity in diverse areas such as finance, insurance, superannuation and environmental regulation. The project aims to propose and solve innovatively robust risk optimisation problems under constraints, taking into account the time dynamics. Applications include risk management around natural catastrophes and long-term asset investment of pension funds. The solutions and outcomes are expected to deliver optimal resource allocation proposals and better management of risk exposure in practice.Read moreRead less
Evolutionary analyses of short-read sequences from pooled samples. This project aims to provide biologists with a means of making sound, statistical inferences about evolution by using next-generation data from mixed samples. When biologists make statements about history, they use evolutionary trees, frequently reconstructed from the genetic data of many individuals. Next-generation sequencing provides large amounts of genetic data at low cost, but biologists have difficulty using these data for ....Evolutionary analyses of short-read sequences from pooled samples. This project aims to provide biologists with a means of making sound, statistical inferences about evolution by using next-generation data from mixed samples. When biologists make statements about history, they use evolutionary trees, frequently reconstructed from the genetic data of many individuals. Next-generation sequencing provides large amounts of genetic data at low cost, but biologists have difficulty using these data for evolutionary research, particularly when they sample mixtures of DNA from many individuals. The anticipated value of this project is that it allows evolutionary biologists to capitalise on the benefits of next-generation sequencing, without sacrificing their ability to make reliable inferences about history.Read moreRead less
The key role of black holes in galaxy evolution. This project will determine the effect of black holes on galaxy formation using sophisticated supercomputer simulations of radiation, jets and winds interacting with multi-phase interstellar gas in the host galaxy. The results of these simulations will be calibrated against radio and optical observations and incorporated into larger scale simulations describing the growth of structure in the Universe and the evolution of galaxies. This research is ....The key role of black holes in galaxy evolution. This project will determine the effect of black holes on galaxy formation using sophisticated supercomputer simulations of radiation, jets and winds interacting with multi-phase interstellar gas in the host galaxy. The results of these simulations will be calibrated against radio and optical observations and incorporated into larger scale simulations describing the growth of structure in the Universe and the evolution of galaxies. This research is highly relevant to the future science programs of the Giant Magellan Telescope and the Square Kilometre Array.Read moreRead less