How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at ....How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at improving educational outcomes or counteracting age-related memory decline. Potential future benefits include facilitating the development of drugs to circumvent memory loss resulting from brain diseases, and improving the design of neuromorphic hardware for computing.Read moreRead less
ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resultin ....ARC Centre of Excellence for Electromaterials Science. The ARC Centre of Excellence for Electromaterials Science (ACES) will create next generation electrochemical devices via the precision assembly of nano/micro dimensional components into macroscopic structures. Through the discovery of new materials and structures, and understanding how spatial arrangement in 3D influences chemical, physical and biological properties, ACES will define the cutting edge of Electromaterials Science. The resulting technology breakthroughs will have a direct impact on some of today's most challenging global problems in clean energy, synthetic biosystems, diagnostics and soft robotics. National benefit to Australia will be realised through the creation of new manufacturing industries.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Clocks in crops: exploring the role of circadian rhythms in crop adaptation. The project aims to analyse how the circadian clock provides adaptive advantages in legumes and cereals, two major crop groups of global importance. The project expects to produce new fundamental knowledge about how the clock in these crops coordinates their development, physiology, and metabolism in response to environmental cues. The anticipated outcome is a better understanding of key similarities and differences in ....Clocks in crops: exploring the role of circadian rhythms in crop adaptation. The project aims to analyse how the circadian clock provides adaptive advantages in legumes and cereals, two major crop groups of global importance. The project expects to produce new fundamental knowledge about how the clock in these crops coordinates their development, physiology, and metabolism in response to environmental cues. The anticipated outcome is a better understanding of key similarities and differences in clock functions in different species. Another is knowledge of how the ancient clock gene variants still in use today may limit the current or future performance of those crops. This will provide significant benefits, such as to improve productivity of crop plants in diverse and changing environments.Read moreRead less
ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre wi ....ARC Centre of Excellence for Plant Success in Nature and Agriculture. The ARC CoE for Plant Success in Nature and Agriculture will discover the adaptive strategies underpinning productivity and resilience in diverse plants and deepen knowledge of the genetic and physiological networks driving key traits. Using novel quantitative and computational approaches, the Centre will link gene networks with traits across biological levels, giving breeders an unparalleled predictive capacity. The Centre will accelerate technologies to transfer successful networks into crops and build legal frameworks to secure this knowledge. With a uniquely multidisciplinary team, the Centre will deliver new strategies to address the problems of food security and climate change, establishing Australia as a global leader in these areas.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE200100086
Funder
Australian Research Council
Funding Amount
$420,000.00
Summary
Rapid Deployment Seismic Recorders for Interdisciplinary Antarctic Research. We aim to establish an Antarctic-based set of seismic instruments, a mobile facility, to provide data to help predict how ice sheets will evolve and how the continent under the ice sheets will respond to changes in ice load. Our approach to tackling such significant questions is innovative, and makes use of newly available, rapid deployment instruments that may be deployed in ice by a small team with light logistics. ....Rapid Deployment Seismic Recorders for Interdisciplinary Antarctic Research. We aim to establish an Antarctic-based set of seismic instruments, a mobile facility, to provide data to help predict how ice sheets will evolve and how the continent under the ice sheets will respond to changes in ice load. Our approach to tackling such significant questions is innovative, and makes use of newly available, rapid deployment instruments that may be deployed in ice by a small team with light logistics. Outcomes will include maps of sub-ice sediments and 3D images of the deep Earth. The facility will thus enable new knowledge relating to major ice sheets. Interdisciplinary use of the research will benefit Australia through an improved ability to plan for future sea level rise in areas with large coastal populations.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE170100075
Funder
Australian Research Council
Funding Amount
$315,000.00
Summary
Acoustic liquid handling robotics for bioactive compound discovery. This project aims to use a Labcyte Echo 550 acoustic dispenser with Combination Software to deliver sophisticated assay-ready screening. The Echo is the only liquid handling dispenser for 1536-well microplates and will allow Australian researchers to develop assay miniaturisation. The robotics will provide our nation’s researchers with a distinct competitive edge by enhancing assay sophistication, accuracy and reproducibility wh ....Acoustic liquid handling robotics for bioactive compound discovery. This project aims to use a Labcyte Echo 550 acoustic dispenser with Combination Software to deliver sophisticated assay-ready screening. The Echo is the only liquid handling dispenser for 1536-well microplates and will allow Australian researchers to develop assay miniaturisation. The robotics will provide our nation’s researchers with a distinct competitive edge by enhancing assay sophistication, accuracy and reproducibility while reducing cost. The expected benefits will advance the elucidation of molecular mechanisms involved in complex biological phenomena. The benefits of this are substantial, including reduction in test compound and reagents, which in turn reduces laboratory costs, conserves cells and increases data quality.Read moreRead less
Robotic investigation of water optical properties in the Southern Ocean. The project aims to improve our understanding of light–matter interactions in the waters of the Southern Ocean (SO), in particular the role of phytoplankton and associated material of biological origin. Phytoplankton are the energy source for the food web and a critical component of carbon cycling in the SO. However, their dynamics in the SO cannot be quantified using satellite observations because bio-optical data processi ....Robotic investigation of water optical properties in the Southern Ocean. The project aims to improve our understanding of light–matter interactions in the waters of the Southern Ocean (SO), in particular the role of phytoplankton and associated material of biological origin. Phytoplankton are the energy source for the food web and a critical component of carbon cycling in the SO. However, their dynamics in the SO cannot be quantified using satellite observations because bio-optical data processing algorithms perform poorly due to a lack of field data. This project seeks to remedy this by improving understanding of SO bio-optics, and by providing novel algorithms of known uncertainty, based on in situ data.Read moreRead less
Mitigating ecosystem impacts by improving the way we breed and manage devils. The Tasmanian ecosystem faces irreversible change due to the decline of the apex predator. An insurance population of Tasmanian devils has been established to prevent extinction of the species. Using the latest sequencing technologies the project aims to determine whether the Tasmanian ecosystem can be restored with Tasmanian devils that are more resilient to a changing environment by improving the way that devils are ....Mitigating ecosystem impacts by improving the way we breed and manage devils. The Tasmanian ecosystem faces irreversible change due to the decline of the apex predator. An insurance population of Tasmanian devils has been established to prevent extinction of the species. Using the latest sequencing technologies the project aims to determine whether the Tasmanian ecosystem can be restored with Tasmanian devils that are more resilient to a changing environment by improving the way that devils are bred and managed in captivity.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100105
Funder
Australian Research Council
Funding Amount
$570,000.00
Summary
Broadband receivers for AuScope geodetic and astronomical applications . Broadband receivers for AuScope geodetic and astronomical applications: This project aims to develop an innovative broadband receiver system which will be deployed on the AuScope array of radio telescopes. This will enable the telescopes to play a key role in improving precision navigation both in Australia and throughout the Southern Hemisphere. The new receiver systems will significantly improve the capability of these fa ....Broadband receivers for AuScope geodetic and astronomical applications . Broadband receivers for AuScope geodetic and astronomical applications: This project aims to develop an innovative broadband receiver system which will be deployed on the AuScope array of radio telescopes. This will enable the telescopes to play a key role in improving precision navigation both in Australia and throughout the Southern Hemisphere. The new receiver systems will significantly improve the capability of these facilities for both geodetic and astronomical investigations. Improvements to the accuracy of the terrestrial reference frame in Australia will allow more accurate measurements of changes in sea level, while high precision astrometric observations undertaken with the new receivers will be used to determine the structure of our Milky Way Galaxy.Read moreRead less