How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at ....How do myelinating cells alter brain circuits to facilitate learning? This project aims to identify the brain circuits that receive new insulation and characterise the molecular mediators of this process. This project will apply innovative technologies to understand how the nervous system remains adaptable throughout life. This new knowledge, of the cellular mechanisms that allow brain circuits to remain adaptable throughout life, may have application in the development of interventions aimed at improving educational outcomes or counteracting age-related memory decline. Potential future benefits include facilitating the development of drugs to circumvent memory loss resulting from brain diseases, and improving the design of neuromorphic hardware for computing.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their env ....How plants open up: revealing the evolution of stomatal opening mechanisms. This project aims to identify novel and conserved mechanisms that drive the opening of stomata – plant pores that enable CO2 acquisition for photosynthesis. Stomatal movements strongly affect plant productivity and water use efficiency and have profoundly influenced the earth’s climate and terrestrial ecology. This project will address critical gaps in our understanding of how plants open stomata in response to their environment and the evolutionary history of the genes controlling this fundamental process. A major expected outcome is knowledge of the diversity of stomatal opening pathways, which should ultimately lead to improved predictions of plant responses to environmental change and assist future targeted modification of plant growth.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100155
Funder
Australian Research Council
Funding Amount
$909,079.00
Summary
Advancing 4D fluorescence microscopy within Australia. This multi-institutional proposal aims to establish a state-of-the-art Lightsheet microscope facility in South Australia with enhanced analysis infrastructure and a national user support network. Expectations are, this will transform researcher outcomes for multiple disciplines by facilitating high-resolution four-dimensional interrogation of novel biological processes. Significant benefits will include the ability to image deep within livin ....Advancing 4D fluorescence microscopy within Australia. This multi-institutional proposal aims to establish a state-of-the-art Lightsheet microscope facility in South Australia with enhanced analysis infrastructure and a national user support network. Expectations are, this will transform researcher outcomes for multiple disciplines by facilitating high-resolution four-dimensional interrogation of novel biological processes. Significant benefits will include the ability to image deep within living tissue over long time-scales without inducing phytotoxicity to produce high-impact fundamental and translatable outcomes, the development of novel probes and methodologies, new cross-disciplinary collaborations, and new and unique funding, student training and public engagement opportunities.Read moreRead less
Robotic investigation of water optical properties in the Southern Ocean. The project aims to improve our understanding of light–matter interactions in the waters of the Southern Ocean (SO), in particular the role of phytoplankton and associated material of biological origin. Phytoplankton are the energy source for the food web and a critical component of carbon cycling in the SO. However, their dynamics in the SO cannot be quantified using satellite observations because bio-optical data processi ....Robotic investigation of water optical properties in the Southern Ocean. The project aims to improve our understanding of light–matter interactions in the waters of the Southern Ocean (SO), in particular the role of phytoplankton and associated material of biological origin. Phytoplankton are the energy source for the food web and a critical component of carbon cycling in the SO. However, their dynamics in the SO cannot be quantified using satellite observations because bio-optical data processing algorithms perform poorly due to a lack of field data. This project seeks to remedy this by improving understanding of SO bio-optics, and by providing novel algorithms of known uncertainty, based on in situ data.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100040
Funder
Australian Research Council
Funding Amount
$447,127.00
Summary
Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unra ....Unravelling the genetics of Kangaroo paws for climate-resilient gardens. The project will produce the first DNA-anchored plant lineage map of Kangaroo paws and gain novel insights into their resilient growth characteristics. Using novel genome and data-driven strategies, this project addresses the knowledge gap around the genetic heirloom of more than 200 iconic Kangaroo paw varieties to speed up the breeding of new varieties with enticing leaf patterns and flower colour combinations. While unravelling the inheritability and breeding barriers, immediate industry adoption will boost horticultural breeding programs long-term. This project uses cutting-edge science to enhance industry capacity for providing new Kangaroo paws for climate-resilient urban green spaces on the national and international market.Read moreRead less
The Dark-side of the Milky Way. Astronomers have long sought to determine the 3-dimensional structure of our Galaxy, the Milky Way, with limited success owing to its immense size and obscuration by dust at optical wavelengths. We know more about structure of tens of thousands of other galaxies than we do about the structure of the Milky Way on the far-side of the Galactic Centre. This program will use Australian infrastructure to make the most accurate distance measurements to date of the far-si ....The Dark-side of the Milky Way. Astronomers have long sought to determine the 3-dimensional structure of our Galaxy, the Milky Way, with limited success owing to its immense size and obscuration by dust at optical wavelengths. We know more about structure of tens of thousands of other galaxies than we do about the structure of the Milky Way on the far-side of the Galactic Centre. This program will use Australian infrastructure to make the most accurate distance measurements to date of the far-side of the Milky Way visible from the Southern hemisphere, completing the 3-dimensional picture of our Galaxy. These results will be leveraged to yield accurate distances, providing fundamental information on the stellar masses, luminosities, and ages.Read moreRead less
Geophysical, Galactic, and Extra-Galactic Science with the AuScope and Australian Pathfinder Arrays. Two new radio telescope arrays are under construction in Australia. One is the Australian Square Kilometre Array Pathfinder, near Geraldton. The other is a very long baseline array with antennae near Hobart, Katherine, and Yarragadee. These three antennae work together to observe radio sources far away across the universe. Their observations are used to establish a very accurate coordinate syste ....Geophysical, Galactic, and Extra-Galactic Science with the AuScope and Australian Pathfinder Arrays. Two new radio telescope arrays are under construction in Australia. One is the Australian Square Kilometre Array Pathfinder, near Geraldton. The other is a very long baseline array with antennae near Hobart, Katherine, and Yarragadee. These three antennae work together to observe radio sources far away across the universe. Their observations are used to establish a very accurate coordinate system or reference frame on the earth, to which the global positioning system is aligned. This program will use these new radio telescope arrays to study the Milky Way and other galaxies, and to study continental drift and sea-level rise on the Earth.Read moreRead less
Outflows, Jets and Plumes. This project studies how fluid flows out from a small concentrated object into a second surrounding fluid. New solution methods will be provided, and new results about how these fluid flows evolve will be obtained. These are important problems with significance in modelling underwater explosions. They are also important in astrophysics, and will help explain the shapes of outflows from some stars or galaxies. The outcomes of the project will be a deeper mathematical un ....Outflows, Jets and Plumes. This project studies how fluid flows out from a small concentrated object into a second surrounding fluid. New solution methods will be provided, and new results about how these fluid flows evolve will be obtained. These are important problems with significance in modelling underwater explosions. They are also important in astrophysics, and will help explain the shapes of outflows from some stars or galaxies. The outcomes of the project will be a deeper mathematical understanding of which outflow shapes are stable, and under what circumstances they might become unstable. This will provide valuable information about galaxy shapes, and a new suite of computational methods for solving such problems.Read moreRead less
A detrital apatite archive to track crustal growth. This project will establish apatite as a new tool to study the evolution of the continental crust. The crust shaped the composition of the atmosphere and the oceans with consequences for the evolution of life through the availability of oxygen and nutrients. However, when and how the continental crust was generated remains a core question. Current models for continental crust development rely on the mineral zircon. However, zircons only record ....A detrital apatite archive to track crustal growth. This project will establish apatite as a new tool to study the evolution of the continental crust. The crust shaped the composition of the atmosphere and the oceans with consequences for the evolution of life through the availability of oxygen and nutrients. However, when and how the continental crust was generated remains a core question. Current models for continental crust development rely on the mineral zircon. However, zircons only record the history of evolved rocks. To address this bias we will use the mineral apatite which forms in less evolved rocks. We will develop a detrital apatite database of Pb-Nd (model) ages and integrate this with the zircon record to provide a more holistic description for how our planet developed.Read moreRead less