Strabismus is the pathological misalignment of the eyes associated with loss of binocular vision and is one of the most common human ophthalmological disorders. Patients with comitant strabismus have full eye movements, whereas patients with incomitant strabismus have limited eye movements, which causes the angle of strabismus to vary with gaze direction. This project aims to define genetic contributors to comitant congenital strabismus.
Development Of A Novel Bioengineered Tissue Construct For Repairing The Eye.
Funder
National Health and Medical Research Council
Funding Amount
$335,817.00
Summary
Corneal diseases are often treated using donor tissue transplants. Nevertheless, donor tissue is unsuitable for treating the peripheral or limbal margin of the cornea. We have therefore developed a way to transplant sheets of limbal tissue (epithelium) grown in the laboratory from a patient's own cells, but this tissue lacks a foundation of connective tissue that we believe is essential for sustained healing. Thus, our aim is to develop a novel limbal transplant which contains both layers.
Translating Genetic Determinants Of Glaucoma Into Better Diagnosis And Treatment
Funder
National Health and Medical Research Council
Funding Amount
$9,466,000.00
Summary
Glaucoma is the leading cause of irreversible blindness worldwide. By 2020, it will affect 80 million people, and in Australia over the next decade, the overall cost of glaucoma will reach $4.3 billion per annum. This Program will use genetic advances to personalise treatment. Blindness will be prevented in individuals at highest risk, new ways to treat patients will be developed, and better outcomes for patients will result from less treatment and monitoring of low risk cases.
Most eye diseases have a genetic contribution, whether rare disorders affecting children such as retinoblastoma or congenital cataracts through to common disorders of older people such as myopia, age-related macular degeneration or glaucoma. We will continue our successful research to find genes that cause these diseases and use this to improve patient care and prevent blindness. We will work out how families can use this genetic information to participate in trials to develop new treatments.
Young Adult Myopia: Genetic And Environmental Associations
Funder
National Health and Medical Research Council
Funding Amount
$809,271.00
Summary
Myopia affects 80% of school leavers in the cities of East Asia, 45% of Asian Australian school leavers and is probably on the rise in European Australian adolescents. Increased levels of education and lack of time outdoors are known to increase the risk of myopia. We will examine 2,000 young adults to find the genes that interact with these risk factors. In addition to confirming when these risk factors are most important, identifying molecular pathways opens the avenue of new treatments.
Understanding impact of autonomous vehicles on behaviour and interactions. Understanding impact of autonomous vehicles on behaviour and interactions. This project aims to explore three human factor issues critical to the successful deployment of automated vehicles: factors influencing driver choice of automated vehicle control; interactions between automated and manually controlled vehicles; and driver detection, recognition, and reaction to automated vehicle system failures. Automated vehicles ....Understanding impact of autonomous vehicles on behaviour and interactions. Understanding impact of autonomous vehicles on behaviour and interactions. This project aims to explore three human factor issues critical to the successful deployment of automated vehicles: factors influencing driver choice of automated vehicle control; interactions between automated and manually controlled vehicles; and driver detection, recognition, and reaction to automated vehicle system failures. Automated vehicles are predicted to be transformative, but their ultimate success and expected societal benefits will depend on drivers’ trust in them and on how people choose to use and interact with them. Insights from this research should prepare our society for more automated vehicles on the roadways.Read moreRead less
A novel integrated motorway management system for less congested, more reliable and safer motorways. Motorway traffic congestion poses major economic, social and safety problems, which this project seeks to address through intelligent traffic management solutions as an alternative to massive infrastructure expansion. The project’s innovative traffic analysis and control system will reduce periods of congestion and increase driver safety.
Unifying Traffic Modelling and Safety Management for Safer and Faster Roads. This project aims to balance road safety and efficiency as conflicting goals of transport systems mixed with connected and automated vehicles (CAVs). This project is expected to generate fundamental knowledge on operational algorithms and analytics for CAVs and develop innovative tools for operating them. Expected outcomes include ground-breaking models capable of the co-estimation of efficiency and safety impacts of CA ....Unifying Traffic Modelling and Safety Management for Safer and Faster Roads. This project aims to balance road safety and efficiency as conflicting goals of transport systems mixed with connected and automated vehicles (CAVs). This project is expected to generate fundamental knowledge on operational algorithms and analytics for CAVs and develop innovative tools for operating them. Expected outcomes include ground-breaking models capable of the co-estimation of efficiency and safety impacts of CAVs, and control strategies to safely and efficiently integrate CAVs into existing transport systems. This should provide significant safety and efficiency benefits that currently cost about 1160 lives and 1.25 billion hours of congestion per year, and make Australia better prepared for the connected and automated vehicle era.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE130100205
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Optimisation of transit priority in a transportation network. This project is aimed at developing an optimised approach to combine various types of public transport priority in an urban network which can be used by transport planners to increase the efficiency of traffic movements and reduce traffic congestion. The case study is the network of Brisbane including all arterial and local roads.