Dissecting The Pseudoexfoliation Syndrome With Complementary Genetic, Proteomic And Biophysical Strategies
Funder
National Health and Medical Research Council
Funding Amount
$490,352.00
Summary
Pseudoexfoliation syndrome (PEX) is an eye condition in which flaky material deposits in the eye, greatly increasing the risk of cataract and glaucoma which can lead to blindness. PEX is also associated with heart disease, strokes and aneurysms. Cataract surgery in PEX patients has a higher rate of complications. In this project we will determine the nature of PEX material and why it forms. This knowlege will facilitate better diagnosis and treatment of PEX preventing associated blindness.
A Genome-wide Association Scan To Identify Genetic Risk Factors For Sight Threatening Diabetic Retinopathy
Funder
National Health and Medical Research Council
Funding Amount
$982,203.00
Summary
Diabetic eye disease is an important complication of diabetes that can lead to blindness. Very little is known about how diabetes causes eye disease, but genetics is known to play a role. We aim to identify genes that contribute to eye disease in diabetes patients. We will compare genes between patients with diabetes with and without severe diabetic eye disease using cutting edge genomic technology. We hope to be able to better predict risk of blindness and to move towards novel treatments.
Industrial Transformation Research Hubs - Grant ID: IH180100002
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Driving Farming Productivity and Disease Prevention. The ARC Research Hub for Driving Farming Productivity and Disease Prevention aims to increase farm production and disease prevention through advancing and transferring new artificial intelligence technologies into industrial deployment. The Hub will combine machine vision, machine learning, software quality control, engineering, biology, and farming industries to develop technologies to build more intelligent systems. Thes ....ARC Research Hub for Driving Farming Productivity and Disease Prevention. The ARC Research Hub for Driving Farming Productivity and Disease Prevention aims to increase farm production and disease prevention through advancing and transferring new artificial intelligence technologies into industrial deployment. The Hub will combine machine vision, machine learning, software quality control, engineering, biology, and farming industries to develop technologies to build more intelligent systems. These dynamic systems will help determine what goal to achieve and the most efficient plan to achieve it. This Hub is expected to contribute to higher farming efficiency, lower production costs and fewer disease risks, giving the Australian industry new business opportunities and an international competitive advantage.Read moreRead less
Evolution. Morphodynamics and History of the Younghusband Peninsula. This project will examine the history and evolution of the Sir Richard-Younghusband Peninsula (SRYP) complex barrier in SA. The aims are to derive a understanding of how the influences of relative sea-level changes, neotectonics, and sediment supply, can produce remarkably different responses in barrier development. No complex barrier (i.e. foredune ridges in one portion, transgressive dunefields in another) has ever been compr ....Evolution. Morphodynamics and History of the Younghusband Peninsula. This project will examine the history and evolution of the Sir Richard-Younghusband Peninsula (SRYP) complex barrier in SA. The aims are to derive a understanding of how the influences of relative sea-level changes, neotectonics, and sediment supply, can produce remarkably different responses in barrier development. No complex barrier (i.e. foredune ridges in one portion, transgressive dunefields in another) has ever been comprehensively drilled, dated, modelled, or examined in the context of indigenous occupation and oral histories in Australia. The study provides excellent analogues for barrier and dune response, and shoreline translation to varying rates of sea level rise, paralleling pressures facing all coastlines today.Read moreRead less
Evolution, disease and extinction - using ancient and modern Deoxyribonucleic acid (DNA) to investigate molecular evolution in the Tasmanian devil. The Tasmanian devil is Australia's largest living marsupial carnivore and one of Tasmania's key tourism icons. Extinction in the wild will have long-term impacts on Tasmanian native ecosystems and economy. This study will provide critical genetic data and tools to monitor and prioritise conservation strategies, including insurance populations and dis ....Evolution, disease and extinction - using ancient and modern Deoxyribonucleic acid (DNA) to investigate molecular evolution in the Tasmanian devil. The Tasmanian devil is Australia's largest living marsupial carnivore and one of Tasmania's key tourism icons. Extinction in the wild will have long-term impacts on Tasmanian native ecosystems and economy. This study will provide critical genetic data and tools to monitor and prioritise conservation strategies, including insurance populations and disease suppression, aimed at preventing extinction. It will strengthen ongoing conservation programs carried out by the Save the Tasmanian Devil Program and will help publicise the plight of the devil both nationally and internationally.Read moreRead less
Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and t ....Clothes, fibres and filters that reduce pollution by micro and nano debris. This project aims to provide scientifically verified methods to avoid, intercept and redesign products that cause the most abundant type of marine plastic pollution – clothing fibres - which has increased by over 450% in 60 years. It will determine how natural and plastic fibres, clothing brands and washing machine filters, alter fibre emissions and ecological impacts. This will enable protocols to improve products and the environment, and reduce health risks that will benefit the public, government regulation and companies in designing "eco-friendly" products.Read moreRead less
Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptuali ....Fostering school attendance for students in Out-of-Home Care. This project aims to investigate why children and young people in Out-Of-Home-Care in Australia are absent from school far more than their peers. The project expects to generate new knowledge about the reasons for their absences and to develop solutions to improve attendance through: children’s own voices; detailed absence data; policy audit; and case studies of promising practice. Expected outcomes include a comprehensive conceptualisation of absences including those triggered by schools or the care context; and an evidence-informed, child-centred framework to enable attendance and, thereby, improved educational outcomes. This should provide significant social and economic benefits both for children in care and for the community. Read moreRead less
Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professiona ....Predicting health, well-being, and educational success in emerging adults: An 8 year longitudinal study. This project will inform the community about factors that affect the psychological, physical, academic, and employment outcomes of emerging adults. It will improve our knowledge of why some young people do not reach their full potential. The project will provide a comprehensive assessment of factors associated with well-being across several domains. It will better equip and assist professionals to identify early those youth at risk of having poor psychological, health, and employment prospects post-school. The project will inform the development of intervention programs for young people and maximise their overall adjustment and well-being several years later.Read moreRead less
A Roadmap for Greening Existing Australian Housing. The project will minimise the impact of the Greenhouse Pollution Reduction Scheme and anticipated rises in water costs on the householders. It will assist the consumers and the building industry in evaluating the environmental and economic costs and benefits of specific retrofitting actions for building envelope and major fixed appliances (thermal insulation, glazing, air infiltration, hot water, heating/cooling, lighting, low water flow and wa ....A Roadmap for Greening Existing Australian Housing. The project will minimise the impact of the Greenhouse Pollution Reduction Scheme and anticipated rises in water costs on the householders. It will assist the consumers and the building industry in evaluating the environmental and economic costs and benefits of specific retrofitting actions for building envelope and major fixed appliances (thermal insulation, glazing, air infiltration, hot water, heating/cooling, lighting, low water flow and water reuse appliances, and solar photovoltaic systems). In addition to assisting a burgeoning renovation industry, the project will enable accurate assessment of the impacts of the Green Loans Program and guide future national and local energy and water reduction policies. Read moreRead less
The Great Exhibitions and their Lost Indigenous Objects . This project will rediscover the Australian Indigenous objects sent overseas to the Great Exhibitions of the nineteenth and early twentieth centuries. Such objects acted as powerful forms of cultural, political and economic display, and a form of imperial and colonial projection. It will excavate the hidden histories of Indigenous people involved in these events and the many objects lost to Australia. Through collaborative work at communi ....The Great Exhibitions and their Lost Indigenous Objects . This project will rediscover the Australian Indigenous objects sent overseas to the Great Exhibitions of the nineteenth and early twentieth centuries. Such objects acted as powerful forms of cultural, political and economic display, and a form of imperial and colonial projection. It will excavate the hidden histories of Indigenous people involved in these events and the many objects lost to Australia. Through collaborative work at community dialogues, the project will repatriate knowledge and remake connections between objects, museums, and Indigenous people. In doing so, it will bring contemporary Indigenous perspectives to global attention, generate new exhibition possibilities and influence international museum practice.Read moreRead less