Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challe ....Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challenging structural questions that cannot be tackled with conventional techniques. Expected outcomes include new knowledge on challenging membrane proteins that allows development of novel strategies for disease control in aquaculture. The data may also be applicable to crop protection from related plant pathogens.Read moreRead less
Marine flatworm parasites of elasmobranchs: a unique model for experiments exploring invasion strategies, biology and specificity to help understand parasitism. Primitive parasites with simple life cycles from ancient hosts emphasise adaptations to parasitism. Experimental studies on live eggs and infective stages of different monogenean (flatworm) parasite species from the skin, gills and cloaca of southern fiddler rays will identify critical interactions early in parasite-host relationships t ....Marine flatworm parasites of elasmobranchs: a unique model for experiments exploring invasion strategies, biology and specificity to help understand parasitism. Primitive parasites with simple life cycles from ancient hosts emphasise adaptations to parasitism. Experimental studies on live eggs and infective stages of different monogenean (flatworm) parasite species from the skin, gills and cloaca of southern fiddler rays will identify critical interactions early in parasite-host relationships that determine whether or not parasitism occurs. Basic and applied benefits include: development of a tractable experimental system for studying parasite-host relationships; strategies to control parasites in public aquaria and aquaculture; profitable and exportable expertise; excellence and research training in basic parasitology; contributions to Australia's natural heritage collections.Read moreRead less
Investing in ecological portfolios: retaining migratory strategies of fish. In finance, investors minimize risk and optimize long term returns by building stock portfolios with different attributes. This contingency strategy also occurs in ecological systems. We will use portfolio effects as a conceptual model to characterise the poorly known sub-population variations in migratory strategies of estuarine fish and their response to environmental conditions. In doing so, we will determine how envi ....Investing in ecological portfolios: retaining migratory strategies of fish. In finance, investors minimize risk and optimize long term returns by building stock portfolios with different attributes. This contingency strategy also occurs in ecological systems. We will use portfolio effects as a conceptual model to characterise the poorly known sub-population variations in migratory strategies of estuarine fish and their response to environmental conditions. In doing so, we will determine how environmental change drives variations in migratory strategies, impacts long-term growth and population trophic web dynamics. Outcomes will foster novel and dynamic management frameworks that enhance population stability despite the predicted volatility of environmental conditions.Read moreRead less
Changing perspective: using fish ear bones to counteract the shifting baseline syndrome. Chemical tracers in fish ear bones from 5,500 years ago through to modern times will provide information on changes in fish ecology over centuries and identify why fish populations have declined. Outcomes will provide knowledge of how fish populations would react to altered fishing pressure and restoration of environments.