Omega-3 fatty acids, appetite and growth in farmed fish. Australia has very limited wild fish supplies, and with the increasing realization of human health benefits of fish (i.e. omega-3 fatty acid) there is a need to increase availability through aquaculture. However, feeds used in aquaculture contain costly fish oil with limited global supplies. Attempts made to substitute fish oil with vegetable sources in aquaculture feeds have been mixed. This international, comparative and multidisciplinar ....Omega-3 fatty acids, appetite and growth in farmed fish. Australia has very limited wild fish supplies, and with the increasing realization of human health benefits of fish (i.e. omega-3 fatty acid) there is a need to increase availability through aquaculture. However, feeds used in aquaculture contain costly fish oil with limited global supplies. Attempts made to substitute fish oil with vegetable sources in aquaculture feeds have been mixed. This international, comparative and multidisciplinary project aims to reduce the dependence on fish oils through investigation of basic fatty acid metabolism and endocrinology on farmed fish to ensure that human health promoting characteristics in the final product are retained.Read moreRead less
Novel enzymatic processing methods and stabilization technologies for omega-3 oils. New and existing lipases will be applied to the concentration of omega-3 lipids from fish and algal oils. The primary aim of this project is to replace current chemical processes and high temperature distillation with milder enzymatic methods, providing high quality omega-3 concentrates for food and pharmaceutical purposes. The project aims to develop new immobilisation technology to enable multiple re-use of lip ....Novel enzymatic processing methods and stabilization technologies for omega-3 oils. New and existing lipases will be applied to the concentration of omega-3 lipids from fish and algal oils. The primary aim of this project is to replace current chemical processes and high temperature distillation with milder enzymatic methods, providing high quality omega-3 concentrates for food and pharmaceutical purposes. The project aims to develop new immobilisation technology to enable multiple re-use of lipases for the cost effective production of omega-3 concentrates and to apply new microencapsulation strategies to the stabilisation of omega-3 concentrates, enabling the delivery of omega-3s and other bioactive ingredients to a range of food and beverage products.Read moreRead less
Removing the impediment to large-scale selective breeding of Australian barramundi: deciphering and manipulating the genetic basis of sex change. This project will determine the genetic basis of sex control in barramundi and develop technologies to allow barramundi hatcheries to have increased control over reproduction leading to more efficient propagation and removing impediments to selective breeding.
Understanding fish-killing mechanisms by harmful algal blooms: towards the design of effective mitigation strategies. Fish-killing microalgal blooms cause multi-million dollar losses to global aquaculture and wild fisheries. This project brings together leading Australian and Canadian research teams, applying sophisticated cell line and biologically active molecule technologies, to elucidate precise fish-kill mechanisms and design effective mitigation strategies.
Fighting disease on farms: how do vaccinations drive evolution of new pathogen strains? Vaccinating against some types of infectious diseases can drive evolution of new variants of the pathogen. This project will show how bacterial populations evolve in response to vaccination in farms, leading to new vaccination strategies and improved vaccine formulations to better control diseases that are caused by highly variable bacteria.
A pan-genome reverse vaccinology approach to disease prevention in farmed fish. Evolution of new pathogen strains causes major problems in vaccinated animals because these variants can reinfect and cause severe disease in previously protected animals. This project will use state-of-the-art genomics to find new targets that are essential to all strain variants, enabling development of broadly cross-protective vaccines for farmed animals.
Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challe ....Characterisation of vital carbohydrate synthases in pathogenic oomycetes. This project aims to understand the mechanisms that control cell wall stability in the fish pathogen, Saprolegnia parasitica. The biochemical properties and function of vital enzymes involved in cell wall biosynthesis will be determined using innovative approaches at the interface of biochemistry, microbiology, cell biology, and structural biology. Next generation ion mobility mass spectrometry will be used to solve challenging structural questions that cannot be tackled with conventional techniques. Expected outcomes include new knowledge on challenging membrane proteins that allows development of novel strategies for disease control in aquaculture. The data may also be applicable to crop protection from related plant pathogens.Read moreRead less