Tree-mediated methane fluxes: A new frontier in the global carbon cycle. Methane is an extremely potent greenhouse gas. Recent evidence suggests that tree-mediated fluxes may be a significant, but overlooked source of methane to the atmosphere. This project aims to quantify the magnitude and drivers of tree-mediated methane fluxes from Australia’s dominant forest types. Innovatively, we will be using a novel combination of empirical field based measurements, gas tracer experiments, microbial ana ....Tree-mediated methane fluxes: A new frontier in the global carbon cycle. Methane is an extremely potent greenhouse gas. Recent evidence suggests that tree-mediated fluxes may be a significant, but overlooked source of methane to the atmosphere. This project aims to quantify the magnitude and drivers of tree-mediated methane fluxes from Australia’s dominant forest types. Innovatively, we will be using a novel combination of empirical field based measurements, gas tracer experiments, microbial analysis and modelling methods. Expected outcomes are a mechanistic understanding of tree-mediated methane fluxes, helping to constrain regional, national and global methane budgets. The results of this study will help inform publicly funded greenhouse gas abatement strategies, ensuring a maximal return on investment.Read moreRead less
Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors w ....Protein biosensors for detecting smoke exposure of grapes. Bush fires and controlled burns that take place in the vicinity of vineyards can lead to grape contamination with tasteless phenolic glucosides. Their hydrolysis during wine making leads to “smoke taint” – an unpleasant medicinal taste that can render wine undrinkable. We will apply a combination of organic synthesis, protein engineering and directed evolution to develop protein-based biosensors of phenolic glucosides. These biosensors will be used to devise a simple portable colorimetric test that can be performed in the vineyard or the winery. The ability to rapidly determine the level of grape contamination with phenolic glucosides would give Australian wine growers and wine makers a powerful tool to mitigate the effects of bushfires.Read moreRead less
Plastic brains: Neural adaptations to changing environments in reptiles. The project aims to quantify brain anatomy on an unprecedented scale in comparative neurobiology. Focusing on Australia’s diverse and extensive collection of reptiles, including goannas, dragons and venomous snakes, the project expects to generate new knowledge on the evolution of brains as these animals adapted to new habitats and climates. Data will be collected by cutting-edge micro-CT technology and advanced phylogeneti ....Plastic brains: Neural adaptations to changing environments in reptiles. The project aims to quantify brain anatomy on an unprecedented scale in comparative neurobiology. Focusing on Australia’s diverse and extensive collection of reptiles, including goannas, dragons and venomous snakes, the project expects to generate new knowledge on the evolution of brains as these animals adapted to new habitats and climates. Data will be collected by cutting-edge micro-CT technology and advanced phylogenetic techniques, which will be complemented by detailed neuroanatomy. Expected outcomes include enhanced understanding of the effects of temperature on brains, and a large database of 3D digital anatomical models. A major benefit includes a greater ability to mitigate the effects of environmental change.Read moreRead less
ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresour ....ARC Centre of Excellence in Plants for Space. ARC Centre of Excellence in Plants for Space. This Centre aims to create on-demand, zero-waste, high-efficiency plants and plant products to address grand challenges in sustainability for Space and on Earth. Significant advances in plant, food, and sensory science; process and systems engineering; law and policy; and psychology are expected to deliver transformative solutions for Space habitation – and create enhanced plant-derived food and bioresources to capitalise upon emergent and rapidly expanding domestic and global markets. Anticipated outcomes include industry uptake of innovative plant forms, foods, technologies, and commodities; and an ambitious education and international co-ordination agenda to position Australia as a global leader in research supporting Space habitation.Read moreRead less
Investigating the evolution of innate and adaptive cellular immunity. This proposal aims to assess the impact of geographical and genetic isolation of the Australian Indigenous population on adaptive and innate immune systems. The project will use novel DNA sequencing approaches to generate the high resolution sequences of two genetic loci that regulate innate and adaptive immune responses, the major histocompatibility complex locus and the killer cell immunoglobulin-like receptor locus. In an i ....Investigating the evolution of innate and adaptive cellular immunity. This proposal aims to assess the impact of geographical and genetic isolation of the Australian Indigenous population on adaptive and innate immune systems. The project will use novel DNA sequencing approaches to generate the high resolution sequences of two genetic loci that regulate innate and adaptive immune responses, the major histocompatibility complex locus and the killer cell immunoglobulin-like receptor locus. In an initial screen, distinct variants and combinations of these genes were identified. This project aims to interrogate how variation in these critical genes impacts on the function of cytotoxic lymphocytes, providing insights into the evolutionary drivers of immune recognition mechanisms.Read moreRead less
Brains frozen in time: vertebrate neural adaptations to invading land . The evolution of terrestrial animals from fish was one of the most significant events in our evolution, yet little is known about how the brain evolved during this transition. This project aims to investigate the major novelties acquired in the evolution of the early vertebrate brain in order to determine the functional reasons for such changes, as well as identifying the timing and environmental factors driving such changes ....Brains frozen in time: vertebrate neural adaptations to invading land . The evolution of terrestrial animals from fish was one of the most significant events in our evolution, yet little is known about how the brain evolved during this transition. This project aims to investigate the major novelties acquired in the evolution of the early vertebrate brain in order to determine the functional reasons for such changes, as well as identifying the timing and environmental factors driving such changes. This project expects to generate new knowledge on the anatomy of the vertebrate brain with improved methods for reconstructing fossil brains to better understand our own neurological evolution. Expected outcomes include enhanced institutional collaborations within Australia, and between Australia, Canada and the USA.Read moreRead less
Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of th ....Threats to the water quality and ecosystem of Coffin Bay, South Australia. Coffin Bay (South Australia) is experiencing worsening environmental conditions despite its major economic and ecological importance. Research is needed to understand the cause of this decline, particularly in light of a recent bacterial outbreak that impacted the aquaculture industry. This multidisciplinary project aims to deliver world-leading scientific advice based on novel field techniques and innovative models of this complex inverse estuary system and its surrounding catchment. The new understanding of the sources, fluxes and fate of nutrients within the bay and the surrounding catchment, arising from this project, is expected to benefit management decision-making and establish a new standard in estuarine water quality investigation.Read moreRead less
Early African woodworking and tool use at the transition to modern humans. Our archaeological excavations and preliminary dating of Amanzi Springs (South Africa) to between 515,000 and 163,000 years ago shows that the site covers a critical time period that led to the origins of our species, Homo sapiens. Amanzi documents, in never before seen resolution, the technological leaps that our ancestors made during this transition. At ~400,000 years ago this includes the oldest evidence for woodworkin ....Early African woodworking and tool use at the transition to modern humans. Our archaeological excavations and preliminary dating of Amanzi Springs (South Africa) to between 515,000 and 163,000 years ago shows that the site covers a critical time period that led to the origins of our species, Homo sapiens. Amanzi documents, in never before seen resolution, the technological leaps that our ancestors made during this transition. At ~400,000 years ago this includes the oldest evidence for woodworking and tool use and >163,000 years ago the oldest heat treatment of rock to make stone tools. The organic preservation at the site means that we can reconstruct changing environment, linked to sea level changes and spring activity, for this period in the evolution of our ancestors at a level of detail not previously possibleRead moreRead less
Epigenetics and Indigenous Australia. This project aims to investigate how epigenetics is being received by Indigenous Australians, and to identify the potential risks and opportunities that narratives of biosocial damage entail. Epigenetics is a rapidly evolving science concerned with how life experiences, such as trauma or stress, can modify DNA and be passed on to negatively affect children's (and possibly grandchildren's) health and development. This project will offer an understanding of th ....Epigenetics and Indigenous Australia. This project aims to investigate how epigenetics is being received by Indigenous Australians, and to identify the potential risks and opportunities that narratives of biosocial damage entail. Epigenetics is a rapidly evolving science concerned with how life experiences, such as trauma or stress, can modify DNA and be passed on to negatively affect children's (and possibly grandchildren's) health and development. This project will offer an understanding of the relationships between Indigenous health and epigenetics that will help Indigenous researchers, policymakers, and government bodies make well-informed decisions about the application and direction of this new science. The research will make a significant contribution to understanding how the interplay of biology, race, and society unfold at the intersection of different knowledge systems and at the forefront of technological progress.Read moreRead less