The Cherbourg Project: Building Capacity For FASD Screening And Diagnosis
Funder
National Health and Medical Research Council
Funding Amount
$717,501.00
Summary
The House of Representatives 2012 Inquiry into Fetal Alcohol Spectrum Disorders (FASD) noted the particular need for research, training and capacity-building relating to FASD in ATSI communities.This project, in collaboration with Cherbourge community in Queensland and the WHO, addresses several Inquiry recommendations by providing: training to increase local capacity to screen/diagnose FASD; community education; diagnostic service for FASD; FASD prevalence data; and data to inform service provi ....The House of Representatives 2012 Inquiry into Fetal Alcohol Spectrum Disorders (FASD) noted the particular need for research, training and capacity-building relating to FASD in ATSI communities.This project, in collaboration with Cherbourge community in Queensland and the WHO, addresses several Inquiry recommendations by providing: training to increase local capacity to screen/diagnose FASD; community education; diagnostic service for FASD; FASD prevalence data; and data to inform service provision and prevention programs.Read moreRead less
LIFECYCLE - Early Life Stressors And LifeCycle Health
Funder
National Health and Medical Research Council
Funding Amount
$453,811.00
Summary
Early in life is a period of time during which we can institute changes that can have long lasting benefits for asthma, obesity, diabetes mellitus and mental and cardiovascular health. The current project, LIFECYCLE is a cooperative project with a combined total of a quarter of a million participants, which will be the definitive study to determine, which early life events should be modified for improving health trajectories throughout life.
Improving The Management Of Youth With Fetal Alcohol Spectrum Disorder In The Justice System
Funder
National Health and Medical Research Council
Funding Amount
$1,499,897.00
Summary
Rates of Aboriginal youth incarceration in Western Australia are among the highest nationally. There is an urgent need to understand the extent of involvement of youth with fetal alcohol spectrum disorders (FASD) in the justice system, and develop strategies to prevent continued engagement with the justice system. This research will establish the first Australian estimate of FASD among youth in detention and develop and evaluate a new model of service delivery and clinical management.
Behaviour Support Training For Fetal Alcohol Spectrum Disorder
Funder
National Health and Medical Research Council
Funding Amount
$659,789.00
Summary
This project will assist parents and carers of children affected by fetal alcohol exposure to manage their behaviour problems. It will utilise the widely researched and applied Australian program "Triple P", enhanced for these families. The project will take place in Fitzroy Crossing, WA, a community which has already shown great resourcefulness in addressing this problem. If successful, the current poor outlook for these children will be greatly improved.
Formulating New Goals For Global Health And Proposing New Governance For Global Health That Will Allow The Achievement Of These Goals
Funder
National Health and Medical Research Council
Funding Amount
$469,017.00
Summary
The Millennium Development Goals have guided global development since 2000, and are due for evaluation in 2015. Attention is now turning to New Health-Related Goals, with a governance structure to support their implementation. Australian researchers are joining a Go4Health consortium of 13 research institutions to research the development of these goals, examining the input of United Nations agencies and key donors into the process, together with communities, civil society and governments.
LIFEPATH: Life-course Biological Pathways Underlying Social Differences In Healthy Ageing
Funder
National Health and Medical Research Council
Funding Amount
$470,466.00
Summary
Healthy ageing varies across society due to environmental, behavioural and social circumstances that affect peoples’ lives. To improve our ability to change this we will investigate suspected biological mechanisms over the life course. Using repeated blood samples collected during a large prospective study, we will measure a very large number of biological markers and analyse these combined with lifestyle and behavioural information to identify the modifiable predictors of healthy ageing.
Hendra virus (HeV) cause a disease transmitted from bats to horses which in turn infect humans and other horses. There are no drugs or vaccines for HeV. Since humans are infected by inhalation, a vaccine that can generate antibody in the lung and protect from infection will be ideal. We have found that a natural sugar called mannan used with virus proteins and administered via the nostrils to generate such responses. In this project we will prepare this vaccine and use it in a mouse model of HeV ....Hendra virus (HeV) cause a disease transmitted from bats to horses which in turn infect humans and other horses. There are no drugs or vaccines for HeV. Since humans are infected by inhalation, a vaccine that can generate antibody in the lung and protect from infection will be ideal. We have found that a natural sugar called mannan used with virus proteins and administered via the nostrils to generate such responses. In this project we will prepare this vaccine and use it in a mouse model of HeV infection to see if it can protect the mice.Read moreRead less
Developing A National Salt Reduction Program For India
Funder
National Health and Medical Research Council
Funding Amount
$935,028.00
Summary
Excess dietary salt is a leading cause of premature strokes and heart attacks around the world. India, the world’s second most populous nation has no coordinated national salt reduction program and lacks key data upon which to formulate a strategy. This research will bring together Australian experts in the field with leading Indian researchers to make the baseline assessments required to formulate and commence population-wide salt reduction efforts in India.
This proposal uses the zebra fish system, which it is uniquely suited to investigate the regulation of disease genes. In all of these diseases preliminary work has already been performed and screening assays have been developed in a previous project (ZF-MODELS). In addition, the project will investigate genetic abnormalities of the eye and visual processing, genetic pathways underlying tissue regeneration and repair, and homologs of human genes related to diabetes and obesity, as well as infecti ....This proposal uses the zebra fish system, which it is uniquely suited to investigate the regulation of disease genes. In all of these diseases preliminary work has already been performed and screening assays have been developed in a previous project (ZF-MODELS). In addition, the project will investigate genetic abnormalities of the eye and visual processing, genetic pathways underlying tissue regeneration and repair, and homologs of human genes related to diabetes and obesity, as well as infectious disease and cancer. The Australian component will perform a systematic characterisation of enhancer elements of potential disease genes. This characterisation will build on the concept of genomic regulatory blocks (GRBs) which contain highly conserved non-coding elements (HCNEs) acting as long-range enhancers of developmental genes (recently discovered by T. Becker in the ZF-MODELS project).Read moreRead less
OptiMalVax: Optimizing A Deployable High Efficacy Malaria Vaccine
Funder
National Health and Medical Research Council
Funding Amount
$494,618.00
Summary
In this proposal, a consortium comprising many of the leading malariologists, vaccine researchers and product developers in Europe, USA, Australia and Africa will collaborate in an exciting programme of antigen discovery science linked to rapid clinical development of new vaccine candidates against malaria.