Regulation Of Caspase-1 Activation And Inflammation By PYD And CARD Proteins
Funder
National Health and Medical Research Council
Funding Amount
$364,549.00
Summary
Inflammatory diseases such as rheumatoid arthritis are among the largest contributors to health expenditure in Australia, and the impact of these diseases will increase dramatically over the next 15-20 years as the population ages. This research will reveal new insights into the regulation of caspase-1 activation and secretion of interleukin-1b, the primary cause of chronic and acute inflammation, and will enhance future approaches for development of treatments for inflammatory disease.