Linking genes with the phenotype - creation of a genetic linkage map for the silver-lipped pearl oyster Pinctada maxima. R&D undertaken in this project will increase our fundamental understanding of the role genetics plays in production of a premium quality cultured South Sea pearl. When utilised in future selective breeding programs aimed at improving pearl quality traits the information generated will allow Australian pearling companies to be more productive and to maintain a competitive advan ....Linking genes with the phenotype - creation of a genetic linkage map for the silver-lipped pearl oyster Pinctada maxima. R&D undertaken in this project will increase our fundamental understanding of the role genetics plays in production of a premium quality cultured South Sea pearl. When utilised in future selective breeding programs aimed at improving pearl quality traits the information generated will allow Australian pearling companies to be more productive and to maintain a competitive advantage over their rivals. Many rural communities are dependent on pearling companies for their economic prosperity and community identity. Consequently, positive growth of the pearl industry as a result of the proposed R&D will greatly benefit the economic and social wealth of these rural populations.Read moreRead less
ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions i ....ARC Complex Open Systems Research Network. Complexity is the common frontier in the physical, biological and social sciences. This Network will link specialists in all three sciences through five generic conceptual and mathematical theme activities. It will promote research into how subsystems self-organise into new emergent structures when assembled into an open, non-equilibrium system. Outcomes will include new technologies and software tools and deeper understanding of fundamental questions in science. An essential function of the network will be introducing researchers end users to new tools and broadening the horizons of graduate students.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE100100064
Funder
Australian Research Council
Funding Amount
$450,000.00
Summary
A facility for sensitive and precise isotopic dating of the earth's and extraterrestrial rocks. SPIDE2R will be a new generation mass spectrometer for very precise and sensitive dating and forensics applications in earth and planetary sciences, hydrology, climate studies, and nuclear and archaeological fingerprinting. The unprecedented sensitivity of this unique instrument will provide enhanced capabilities for solving long-standing problems requiring precise geological time resolution, as well ....A facility for sensitive and precise isotopic dating of the earth's and extraterrestrial rocks. SPIDE2R will be a new generation mass spectrometer for very precise and sensitive dating and forensics applications in earth and planetary sciences, hydrology, climate studies, and nuclear and archaeological fingerprinting. The unprecedented sensitivity of this unique instrument will provide enhanced capabilities for solving long-standing problems requiring precise geological time resolution, as well as opening new areas of research. It will be the instrument of choice for analysing small, rare samples such as those returned by space missions. The Australian-built high sensitivity source and ion detection systems can be retrofitted onto other mass spectrometers, opening a new area of commercialisation.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH180100002
Funder
Australian Research Council
Funding Amount
$5,000,000.00
Summary
ARC Research Hub for Driving Farming Productivity and Disease Prevention. The ARC Research Hub for Driving Farming Productivity and Disease Prevention aims to increase farm production and disease prevention through advancing and transferring new artificial intelligence technologies into industrial deployment. The Hub will combine machine vision, machine learning, software quality control, engineering, biology, and farming industries to develop technologies to build more intelligent systems. Thes ....ARC Research Hub for Driving Farming Productivity and Disease Prevention. The ARC Research Hub for Driving Farming Productivity and Disease Prevention aims to increase farm production and disease prevention through advancing and transferring new artificial intelligence technologies into industrial deployment. The Hub will combine machine vision, machine learning, software quality control, engineering, biology, and farming industries to develop technologies to build more intelligent systems. These dynamic systems will help determine what goal to achieve and the most efficient plan to achieve it. This Hub is expected to contribute to higher farming efficiency, lower production costs and fewer disease risks, giving the Australian industry new business opportunities and an international competitive advantage.Read moreRead less
Special Research Initiatives - Grant ID: SR120200004
Funder
Australian Research Council
Funding Amount
$30,000,000.00
Summary
Australian Synchrotron Access Program. The Australian Synchrotron epitomises scientific research excellence in Australian and New Zealand. Its impact spans nearly every research sector. This proposal brings together over 30 Australian universities working together to ensure that world-class peer-reviewed science continues to be performed at the Australian Synchrotron.
Special Research Initiatives - Grant ID: SR0354636
Funder
Australian Research Council
Funding Amount
$30,000.00
Summary
Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecula ....Australian Computational Molecular Science Network. Computational Molecular Science (CMS) involves the use of theory and computational methods to simulate and visualise molecular systems ranging from small atmospheric species to proteins, nucleic acids, chemical polymers and materials. It represents our most incisive expression of what we understand about the molecular basis of nature. The CMS network will integrate and cross-fertilize both fundamental and application-based expertize in molecular scale computations in the fields of nanoscience, biomaterials, biotechnology, biomedical science and environmental science. It will uncover and explore critical new interdisciplinary science and create new molecular-based paradigms that will drive advances in these fields over the next decade.Read moreRead less
The role of mechanosensitive (MS) ion channels in magnetoreception. The magnetic field of the Earth has for long been known to influence the behaviour and orientation of a variety of organisms. Experimental study of the magnetic sense has however, been impaired by the lack of a plausible cellular and/or molecular mechanism providing meaningful explanation for detection of magnetic fields by living organisms. Recently, mechanosensitive (MS) ion channels have been implied to play a role in magneto ....The role of mechanosensitive (MS) ion channels in magnetoreception. The magnetic field of the Earth has for long been known to influence the behaviour and orientation of a variety of organisms. Experimental study of the magnetic sense has however, been impaired by the lack of a plausible cellular and/or molecular mechanism providing meaningful explanation for detection of magnetic fields by living organisms. Recently, mechanosensitive (MS) ion channels have been implied to play a role in magnetoreception. Based on our preliminary investigations, which suggest that the activity of bacterial MS channels may be affected by magnetic fields, we propose to study effects of magnetic fields on MS ion channels in Gram-negative bacteria Escherichia coli and Magnetospirillum magnetotacticum. The project promises also to contribute towards better understanding of adverse effects of electromagnetic radiation on human health and towards understanding the mechanisms behind remote magnetic-nanoparticle mediated activation of MS ion channels.Read moreRead less
Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics ....Early evolutionary origins of mechanosensory transduction: structure, function and phylogenetic studies of the family of mechanosensitive channels in cell-walled organisms. The proposed project is based on the recent progress the applicants have made by (i) identifying a novel family of mechanosensitive (MS) channels in cell-walled organisms, which include Archaea and Bacteria (prokaryotes), as well as fungi and plants (eukaryotes), and (ii) determining basic aspects of the structural dynamics of MscL, the prototype MS channel, using electronparamagnetic resonance spectroscopy and molecular dynamics simulations in combination with the patch clamp technique. The aim of the project is to elucidate the molecular principles underlying the function of MS channels, which is of fundamental importance for understanding of the biophysics and physiology of mechanosensory transduction throughout the biological world.Read moreRead less
Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid i ....Force from lipids: the role of the lipid bilayer in mechanosensory transduction. The proposed research will significantly contribute to a better understanding of the wide range of physiological processes underlying mechanosensory transduction in living cells. The direct benefit for Australian science consists of: (i) strengthening international links with leading overseas laboratories, and (ii) accessing the state-of-the-art expertise not available in Australia. The acquired knowledge will aid in developing and designing artificial tactile sensors inspired by their biological models studied in this project. Long-term, the project is expected to make an original contribution towards developing new technologies and novel medical applications, both of which promise to be of great national benefit.Read moreRead less
How typical is our Local Galaxy Group? This project will uncover how unusual the Local Group is by comparing the Milky Way and Andromeda Galaxy (known as M31) halos to similar mass systems in the local Universe. By using well understood galaxy groups created as part of the Galaxy And Mass Assembly project (GAMA), the study will be able to uncover the mass distribution of galaxies found in different mass groups. It will go further than any previous work by combining these robust groups with faint ....How typical is our Local Galaxy Group? This project will uncover how unusual the Local Group is by comparing the Milky Way and Andromeda Galaxy (known as M31) halos to similar mass systems in the local Universe. By using well understood galaxy groups created as part of the Galaxy And Mass Assembly project (GAMA), the study will be able to uncover the mass distribution of galaxies found in different mass groups. It will go further than any previous work by combining these robust groups with fainter imaging data. The combination of both datasets will allow the determination of whether the Local Group is typical or unusual. Putting the Local Group into a cosmological context is vital since many future Galactic archaeology surveys assume that it is typical, and can meaningfully inform us about the wider universe.Read moreRead less