Formation, photochemistry and fate of gas-phase peroxyl radicals. This project aims to understand how peroxyl radical reactions modulate the composition of air. The gas-phase chemical reactions of organic peroxyl radicals contribute to air quality in clean and polluted environments. However, experimental observations of these reaction intermediates and the complex mechanisms governing their formation and fate are limited. This project will use mass spectrometry and laser-based methods to interro ....Formation, photochemistry and fate of gas-phase peroxyl radicals. This project aims to understand how peroxyl radical reactions modulate the composition of air. The gas-phase chemical reactions of organic peroxyl radicals contribute to air quality in clean and polluted environments. However, experimental observations of these reaction intermediates and the complex mechanisms governing their formation and fate are limited. This project will use mass spectrometry and laser-based methods to interrogate the chemical and photochemical reactions of peroxyl radicals in the gas phase. This project expects to understand the composition and dynamics of the troposphere and inform strategies to improve air quality.Read moreRead less
Bioinspired interfaces for improved carbon fibre composite performance. Carbon fibre composites, where carbon fibres are embedded in a polymer matrix, are gradually replacing traditional materials such as steel. For example, composites make up 50 per cent of Boeing’s 787 Dreamliner, resulting in a 20 per cent improvement in fuel economy. There is significant scope for improving the damage tolerance of these materials. A fundamental lack of understanding around the fibre matrix interface currentl ....Bioinspired interfaces for improved carbon fibre composite performance. Carbon fibre composites, where carbon fibres are embedded in a polymer matrix, are gradually replacing traditional materials such as steel. For example, composites make up 50 per cent of Boeing’s 787 Dreamliner, resulting in a 20 per cent improvement in fuel economy. There is significant scope for improving the damage tolerance of these materials. A fundamental lack of understanding around the fibre matrix interface currently limits the development of new composite systems to overcome the problems with damage tolerance. This project takes inspiration from nature to develop a fundamental understanding of the interfaces within carbon fibre composites and optimise their behaviour via model-guided surface and interface engineering. Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE140101268
Funder
Australian Research Council
Funding Amount
$386,820.00
Summary
Stochastic mathematical modelling of the Wnt signalling pathway. The Wnt signalling pathway is pivotal in multicellular organisms, regulating cellular processes such as proliferation, apoptosis and migration. Faulty Wnt signalling is associated with degenerative diseases, developmental disorders and cancers and is therefore a potential target for therapeutic drugs. This project will perform a stochastic spatial simulation of the Wnt signalling pathway which will be matched to experimental data. ....Stochastic mathematical modelling of the Wnt signalling pathway. The Wnt signalling pathway is pivotal in multicellular organisms, regulating cellular processes such as proliferation, apoptosis and migration. Faulty Wnt signalling is associated with degenerative diseases, developmental disorders and cancers and is therefore a potential target for therapeutic drugs. This project will perform a stochastic spatial simulation of the Wnt signalling pathway which will be matched to experimental data. The model will be extended to integrate with the cell cycle. Increased proliferation in tumours has been linked to mutations in Wnt components. Using the extended model, the effect of Wnt-targeting therapeutic cancer drugs on cancer cell proliferation rates will be predicted and compared to experiments.Read moreRead less
High-productivity ammonia electrosynthesis. The aim of this project is to develop and demonstrate high-performance devices for ammonia production from renewables by a scalable electrolysis method. This will be achieved by experimental and modelling investigations of the nitrogen reduction reaction to guide the design of tailor-made cathodes. New knowledge in catalysis and materials science is expected to be generated. The target outcome of the project is a sustainable and affordable ammonia synt ....High-productivity ammonia electrosynthesis. The aim of this project is to develop and demonstrate high-performance devices for ammonia production from renewables by a scalable electrolysis method. This will be achieved by experimental and modelling investigations of the nitrogen reduction reaction to guide the design of tailor-made cathodes. New knowledge in catalysis and materials science is expected to be generated. The target outcome of the project is a sustainable and affordable ammonia synthesis method as an alternative to the current fossil-fuels-based and excessively greenhouse-emitting process. The technology to be developed in this project is anticipated to be of significant benefit to the Australian agriculture sector as a local, on-demand source of low-cost fertilisers.Read moreRead less
A molecular understanding of transport fuels to drive clean and efficient combustion. A molecular understanding of hydrocarbon combustion remains incomplete and this inhibits the deployment of alternative fuels and clean/efficient engine technologies. This project will develop the chemistry that will enable accurate combustion models to accelerate developments towards clean and efficient fuels for the twenty-first century.
Transformation of organics in the unpolluted atmosphere. This project will develop the chemistry needed to model the removal of methane and other organic compounds from the unpolluted atmosphere. While the chemistry of urban environments is now understood, there are major shortcomings when describing remote environments, limiting our ability to model the lifetimes of key greenhouse gases and toxins.
The New Oxidation Chemistry of Amines. Organic compounds containing nitrogen, including amines, are distributed throughout the atmosphere, where they are removed through oxidation reactions. Surprisingly little attention, however, has been directed towards the oxidation chemistry of amines. This problem is of growing importance as the leading technology for carbon capture from power stations involves amine solvents, which would potentially lead to large new sources of amines to the atmosphere. T ....The New Oxidation Chemistry of Amines. Organic compounds containing nitrogen, including amines, are distributed throughout the atmosphere, where they are removed through oxidation reactions. Surprisingly little attention, however, has been directed towards the oxidation chemistry of amines. This problem is of growing importance as the leading technology for carbon capture from power stations involves amine solvents, which would potentially lead to large new sources of amines to the atmosphere. This project will develop the new chemistry required to describe the oxidation of amines in the atmosphere, in order to better predict the impact of these under-studied molecules on air quality.Read moreRead less