5D Imaging Flow Cytometry for in vivo Quantification of Biological Fluids. Rapid and accurate quantification of live biological fluid properties at sub-cellular and molecular levels forms the bedrock of biofluidic sciences. Majority of the biofluidic devices rely on quantifying biological fluids after its removal from the body in an in vitro Flow Cytometer (FC). FC faces many caveats i.e. biological degradation and small volume etc. In this project, we shall engineer the first in vivo 5D imaging ....5D Imaging Flow Cytometry for in vivo Quantification of Biological Fluids. Rapid and accurate quantification of live biological fluid properties at sub-cellular and molecular levels forms the bedrock of biofluidic sciences. Majority of the biofluidic devices rely on quantifying biological fluids after its removal from the body in an in vitro Flow Cytometer (FC). FC faces many caveats i.e. biological degradation and small volume etc. In this project, we shall engineer the first in vivo 5D imaging flow cytometer (5D IFC) capable of continuous assessment of potentially entire blood volume in a living mice without removing fluid out of the body. The project represents a major advancement beyond any existing flow cytometer and overcome the engineering limits of state-of-art laser scanning imaging devices.Read moreRead less
The fluid mechanics of dynamically constricted tubes in pulsatile flow. This project is aimed at advancing the fundamental understanding of flow instability, the transition to turbulence and the effect on wall shear stress, in a dynamically constricted tube flow. The project will provide the first accurately resolved experimental flow analysis, using tomographic particle imaging velocimetry and 3D laser doppler anemometry, conducted on a novel experimental model, and will resolve, for the first ....The fluid mechanics of dynamically constricted tubes in pulsatile flow. This project is aimed at advancing the fundamental understanding of flow instability, the transition to turbulence and the effect on wall shear stress, in a dynamically constricted tube flow. The project will provide the first accurately resolved experimental flow analysis, using tomographic particle imaging velocimetry and 3D laser doppler anemometry, conducted on a novel experimental model, and will resolve, for the first time, turbulence characteristics of the dynamic constriction, using direct numerical simulation with a novel moving boundary implementation. The outcomes will provide the key link between fluid mechanics and wall shear stress, allowing future progress to be made in elucidating the causes of cardiovascular disease.
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Scaling laws for aerodynamics of moving wings in the Martian atmosphere. This project aims to increase understanding of the aerodynamics of bio-inspired flight in the low-density atmosphere of Mars. The significance of flight in planetary exploration is shown by the ongoing success of the Ingenuity helicopter on Mars, and the Dragonfly rotorcraft planned for use on Titan. Expected outcomes of this project will be innovative numerical modelling techniques validated using local specially designed ....Scaling laws for aerodynamics of moving wings in the Martian atmosphere. This project aims to increase understanding of the aerodynamics of bio-inspired flight in the low-density atmosphere of Mars. The significance of flight in planetary exploration is shown by the ongoing success of the Ingenuity helicopter on Mars, and the Dragonfly rotorcraft planned for use on Titan. Expected outcomes of this project will be innovative numerical modelling techniques validated using local specially designed low-pressure experimental facilities. Benefits will be more accurate design guidance for efficient and robust flapping and rotary wing robotic vehicles for Mars and other space exploration that take advantage of the unique atmospheric conditions, and in placing Australia at the forefront of such design technology.Read moreRead less
Novel framework for optimising battery-cooling microchannel heat exchangers. Thermal overheating can affect the capacity, safety and life expectancy of batteries for renewable energy storage and electric vehicles. Microscale heat exchangers are a potential high-efficiency, low-bulk solution. This project aims to develop a novel computational methodology to optimise the design of those heat exchangers in which viscoelastic fluids are used to control flow instabilities and enhance heat transfer at ....Novel framework for optimising battery-cooling microchannel heat exchangers. Thermal overheating can affect the capacity, safety and life expectancy of batteries for renewable energy storage and electric vehicles. Microscale heat exchangers are a potential high-efficiency, low-bulk solution. This project aims to develop a novel computational methodology to optimise the design of those heat exchangers in which viscoelastic fluids are used to control flow instabilities and enhance heat transfer at the microscale. A new microscopic fluid physics model will provide data for an innovative neural network framework to optimise the working fluid conditions and microscale design, which could contribute to increased adoption of renewable energy technologies that are supported by microscale heat exchangers.Read moreRead less
Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the ....Thermal Optimisation of Gigascale Solar Photovoltaics. Large-scale solar photovoltaics are critical to decarbonising the global economy. Sun Cable is developing the world’s largest solar farm in the Northern Territory, and is considering deploying the 5B MAV solar array. At this scale, temperature-induced panel efficiency losses represent a major challenge that must be overcome through thermal performance optimisation. We will build sophisticated multiscale models to simulate and understand the multiple interacting phenomena that cause panel heating, for the first time. This project will create the tools and know-how to optimise array design and solar farm development, delivering major efficiency gains and enhancing the viability of future gigascale solar projects.Read moreRead less
Quantifying vertical and lateral ocean transport due to fronts and eddies. This project aims to quantify the intensity and location of ocean currents at unprecedented fine spatial scales by using data from a new generation of high-resolution satellites. These fine scales dominate the lateral and vertical transport of ocean-borne material, including heat, larvae and pollutants like oil and plastics, yet are poorly understood. New algorithms for processing satellite data will be developed and test ....Quantifying vertical and lateral ocean transport due to fronts and eddies. This project aims to quantify the intensity and location of ocean currents at unprecedented fine spatial scales by using data from a new generation of high-resolution satellites. These fine scales dominate the lateral and vertical transport of ocean-borne material, including heat, larvae and pollutants like oil and plastics, yet are poorly understood. New algorithms for processing satellite data will be developed and tested using in situ data in the significant North West Shelf region. Expected outcomes will be novel methods to identify ocean currents and a paradigm shift in quantification of fine-scale ocean dynamics. This will benefit operational oceanography in the areas of maritime safety, defence, fisheries and the offshore industry.Read moreRead less
Role of modulating water wave groups in enhancing air-water fluxes. This project aims to investigate the importance of the group structure and breaking of wind-generated waves of various scales in the air-water exchange of mass, momentum and energy. This project expects to generate new understanding in the area of air-water exchanges using an innovative approach based on direct numerical simulation of wind over unsteady water wave groups for a wide range of wind speed and wave steepness conditi ....Role of modulating water wave groups in enhancing air-water fluxes. This project aims to investigate the importance of the group structure and breaking of wind-generated waves of various scales in the air-water exchange of mass, momentum and energy. This project expects to generate new understanding in the area of air-water exchanges using an innovative approach based on direct numerical simulation of wind over unsteady water wave groups for a wide range of wind speed and wave steepness conditions.
Expected outcomes of this project include generating fundamental knowledge of the unresolved physics and new parameterisations for air-water exchange rates. This will deliver more accurate and more comprehensive forecast models for weather, inland and ocean waterways, and numerous industrial processes.Read moreRead less
Fluid-structure-acoustics interactions of bio-inspired flapping wings. This project aims to produce a deeper understanding of the role of wingtip feathers in the remarkable abilities of birds to fly in unsteady and unpredictable aerodynamic environments, and in some cases to do so almost silently. This is achieved by developing novel numerical methods integrating fluid, structure and acoustics interactions for large deformations and complex geometries. The numerical results are validated and com ....Fluid-structure-acoustics interactions of bio-inspired flapping wings. This project aims to produce a deeper understanding of the role of wingtip feathers in the remarkable abilities of birds to fly in unsteady and unpredictable aerodynamic environments, and in some cases to do so almost silently. This is achieved by developing novel numerical methods integrating fluid, structure and acoustics interactions for large deformations and complex geometries. The numerical results are validated and complemented by using flow, structure and acoustics experiments on dynamically scaled models. The insight gained provides design guidance for more efficient, robust and stable flight of bio-inspired micro air vehicles, and in reducing the noise impact of wind turbines by innovative blade leading edge and tip shaping.Read moreRead less
Violation of fundamental symmetries in atoms, molecules and nuclei. This theoretical project aims to predict enhanced effects of parity (P), time reversal (T), CP and Lorentz invariance violation, which may be measured using atomic spectroscopy and nuclear physics methods. This project expects to contribute to search for physics beyond standard model, including standard model extensions predicting axion, dark matter and T,P-violating electric dipole moments. Expected outcomes include predictions ....Violation of fundamental symmetries in atoms, molecules and nuclei. This theoretical project aims to predict enhanced effects of parity (P), time reversal (T), CP and Lorentz invariance violation, which may be measured using atomic spectroscopy and nuclear physics methods. This project expects to contribute to search for physics beyond standard model, including standard model extensions predicting axion, dark matter and T,P-violating electric dipole moments. Expected outcomes include predictions of new enhanced effects in nuclei, atoms and molecules. By-products and benefits include development of high precision computer codes for atomic calculations, which are expected to have numerous applications including photon and electron processes, properties of superheavy elements and atomic clocks.Read moreRead less
Violation of fundamental symmetries in atomic phenomena. Violation of the fundamental symmetries is predicted by unification theories of elementary particles. The aim of this project is to propose new enhanced effects of parity, time reversal and Lorentz invariance violations and perform their calculations needed to test unification theories in atomic and nuclear phenomena. By-products of this project include development of high precision computer codes for atomic calculations and theory of pro ....Violation of fundamental symmetries in atomic phenomena. Violation of the fundamental symmetries is predicted by unification theories of elementary particles. The aim of this project is to propose new enhanced effects of parity, time reversal and Lorentz invariance violations and perform their calculations needed to test unification theories in atomic and nuclear phenomena. By-products of this project include development of high precision computer codes for atomic calculations and theory of processes involving atoms and nuclei in chaotic excited states. These codes and theory are expected to have numerous applications (e.g. search for Dark Matter and atomic spectra of superheavy elements, atomic clocks and electron and photon processes).
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