Complex trait analyses based on genome-wide approaches. This project aims to develop whole genome approaches that can improve the estimation and prediction power by using information from the dynamic genetic architecture of complex traits (i.e. the changes of genetic characteristics and effects when varying effective population size and genetic backgrounds). The project intends to deliver advanced statistical models, efficient algorithms and design by combining data from close relatives, populat ....Complex trait analyses based on genome-wide approaches. This project aims to develop whole genome approaches that can improve the estimation and prediction power by using information from the dynamic genetic architecture of complex traits (i.e. the changes of genetic characteristics and effects when varying effective population size and genetic backgrounds). The project intends to deliver advanced statistical models, efficient algorithms and design by combining data from close relatives, population samples or from different populations (e.g. multi-ethnicities or multi-breeds). The expected outcome is to better understand the dynamic architecture of complex traits and develop methods with improved power, precision and accuracy in genomic analyses.Read moreRead less
Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biologic ....Organic Bionics: Soft Materials to Solve Hard Problems in Neuroengineering. This project aims to combine innovations in organic conductors, nanotechnology, 3D biofabrication and neuroengineering to develop a bioelectronic system capable of wireless neuromodulation with unprecedented stability and precision. This project expects to generate new knowledge regarding the properties of materials that promote optical neuromodulation and new strategies to obtain long-term material stability in biological environments. The expected outcome is to generate new material design rules to facilitate wireless neuromodulation technologies in biomedical engineering. The project will position Australia as a leader in bionic devices by creating a new 3D bioprinting hub for low-cost fabrication of bioelectronic systems.Read moreRead less
Understanding the evolutionary tempo and significance of the first animals through exceptional fossil preservation. This project will shed new light on the origins and early evolutionary history of the first complex marine animals that appeared over half a billion years ago. Extraordinarily preserved fossils, including soft tissues, from South Australia will highlight the rapid anatomical innovation that occurred during this crucial phase in the history of life.
How is information organised in the mind? Learning structured mental representations from data. One of the biggest questions in psychology is to understand the principles that the mind uses to organise information. This project is both a search for these underlying psychological laws, and an attempt to develop new statistical technologies and mathematical tools that can be used to organise information in applied settings.
Internally decorated discrete Metallo-supramolecular Assemblies and infinite Metal-Organic Frameworks as molecular containers. In the macroscopic world, containers are used to hold, provide physical protection, or create a modified environment for their contents. This project will result in the synthesis of novel molecular container materials that provide decorated internal surfaces capable of selectively binding chemical species. In addition to the breakthrough scientific benefits of establish ....Internally decorated discrete Metallo-supramolecular Assemblies and infinite Metal-Organic Frameworks as molecular containers. In the macroscopic world, containers are used to hold, provide physical protection, or create a modified environment for their contents. This project will result in the synthesis of novel molecular container materials that provide decorated internal surfaces capable of selectively binding chemical species. In addition to the breakthrough scientific benefits of establishing the fundamentals of these systems, the binding of chemicals, which are environmental contaminants, will provide the grounding for applications that will contribute to the national priority of 'Frontier technologies'. Furthermore, this research will lead to the training of the next generation of Australian scientists by quality international researchers.Read moreRead less
Targeting chloroplasts to enhance crop salt tolerance. Yield losses in crop plants due to increasingly saline soils are linked to the effects of salt on chloroplasts. By comparing chloroplast water- and salt-transport mechanisms of closely related salt-loving and salt-sensitive plants, this Fellowships aims to discover how chloroplasts maintain function in saline conditions. Novel biophysics and molecular techniques will be used to characterise transporters in model plants, and proof-of-concept ....Targeting chloroplasts to enhance crop salt tolerance. Yield losses in crop plants due to increasingly saline soils are linked to the effects of salt on chloroplasts. By comparing chloroplast water- and salt-transport mechanisms of closely related salt-loving and salt-sensitive plants, this Fellowships aims to discover how chloroplasts maintain function in saline conditions. Novel biophysics and molecular techniques will be used to characterise transporters in model plants, and proof-of-concept complementation experiments aim to confer salt tolerance on sensitive plants. These fundamental insights are likely to lead to rapid, step-change improvements in salt tolerance, especially in agriculturally relevant crops, to benefit Australia’s agri-industry and ensure food security in the future.Read moreRead less
From individuals to mass organisation: aggregation, synchronisation and collective movement in locusts. By combining field biology, robotics and mathematics, this project will determine how animals flock or swarm and, in particular, how locust nymphs control their collective movement over their lifetime. The mathematical models derived during the project will be directly applied to controlling outbreaks of locusts in Australia, South and North Africa.
Ringed photonic crystal fibres for broadband nonlinear optics. The technology developed from this project will enable organic molecules to be detected, identified and quantified. Because the technology is compact, easily engineered and low cost, it will lead to a dramatically increased capability for infrared spectroscopic measurement throughout biology and medicine, with specific benefits in agriculture, the food industry and defence.
Measuring mantle hydrogen to map ore fluids and model plate tectonics. The goal of this project is to use magnetotellurics to measure mantle hydrogen content to aid in the discovery of new mineral deposits. Hydrogen controls the strength of Earth’s mantle and is a vital component of the systems that form giant ore deposits. However, mantle hydrogen content is unconstrained. Ore-forming fluids hydrate the mantle pathways on which they travel. The first aim of this project is to image these fluid ....Measuring mantle hydrogen to map ore fluids and model plate tectonics. The goal of this project is to use magnetotellurics to measure mantle hydrogen content to aid in the discovery of new mineral deposits. Hydrogen controls the strength of Earth’s mantle and is a vital component of the systems that form giant ore deposits. However, mantle hydrogen content is unconstrained. Ore-forming fluids hydrate the mantle pathways on which they travel. The first aim of this project is to image these fluid pathways to improve mineral exploration techniques. Plate tectonic models assume that the lithospheric mantle is dehydrated but existing data from magnetotellurics and mantle rocks show high hydrogen contents. The second aim of this project is to create a map of the hydrogen content of the plates, which may lead to new models for continental evolution and mantle dynamics.Read moreRead less
Early human dispersal: identifying the key environmental drivers. This project aims to investigate if environmental or human evolutionary processes drove the dispersal of early humans eastwards from Africa into Southeast Asia—and beyond into Australia. The project will examine archaeological sediments using an Earth-science approach, providing direct links between cultural and environmental records. The project will reveal the types of environment that were favored by early humans and provide a ....Early human dispersal: identifying the key environmental drivers. This project aims to investigate if environmental or human evolutionary processes drove the dispersal of early humans eastwards from Africa into Southeast Asia—and beyond into Australia. The project will examine archaeological sediments using an Earth-science approach, providing direct links between cultural and environmental records. The project will reveal the types of environment that were favored by early humans and provide a greater understanding of the role of environmental change on the colonisation of new environments. Read moreRead less