Gating, specificity and regulation of the YggB channel protein from Corynebacterium glutamicum. The proposed research will greatly contribute to our understanding of the functioning of a bacterial membrane channel/transporter, which has played a significant role in biotechnology of commercially important amino acids. A direct national benefit will result from establishing collaboration with a leading German laboratory providing expertise in protein biochemistry and molecular microbiology not ava ....Gating, specificity and regulation of the YggB channel protein from Corynebacterium glutamicum. The proposed research will greatly contribute to our understanding of the functioning of a bacterial membrane channel/transporter, which has played a significant role in biotechnology of commercially important amino acids. A direct national benefit will result from establishing collaboration with a leading German laboratory providing expertise in protein biochemistry and molecular microbiology not available in Australia. The acquired knowledge will present an original contribution which will have a strong impact on a very competitive field of molecular microbiology and biotechnology.Read moreRead less
Diagnosis of Reference Flow Control Alerts for the Identification of Malicious Event Sequences (DiagRF). There are a reported two billion computer attacks worldwide per year. Many of these attacks require a skilled human to decipher them and to develop the "signatures" by which they can be detected. The main outcome of this project will be fundamental knowledge regarding how information flows can be tracked and then forensically analysed in a distributed computer system or network in order to ....Diagnosis of Reference Flow Control Alerts for the Identification of Malicious Event Sequences (DiagRF). There are a reported two billion computer attacks worldwide per year. Many of these attacks require a skilled human to decipher them and to develop the "signatures" by which they can be detected. The main outcome of this project will be fundamental knowledge regarding how information flows can be tracked and then forensically analysed in a distributed computer system or network in order to enable the automatic characterization of certain classes of attacks. This new approach will enable the automatic development of attack signatures and thus the detection of such attacks. The project will lead to the development of a prototype which implements the automatic analysis and characterization of such attacks to provide proof of concept.Read moreRead less
Particle Design for Recovery and Delivery of Bioactives. This project will develop new strategies for economically viable recovery of bioactives from complex solutions, slurries and sludges of biomaterials eg. waste streams from milk and soy bean processing, and fermentation broths. These bioactives, often proteins, have growing applications as high value drugs, nutriceuticals and food additives but are difficult to separate and to maintain in an active form. Crystallisation will be used as a ....Particle Design for Recovery and Delivery of Bioactives. This project will develop new strategies for economically viable recovery of bioactives from complex solutions, slurries and sludges of biomaterials eg. waste streams from milk and soy bean processing, and fermentation broths. These bioactives, often proteins, have growing applications as high value drugs, nutriceuticals and food additives but are difficult to separate and to maintain in an active form. Crystallisation will be used as a primary separation technique. Molecular studies of protein interactions will be used to predict good crystallisation conditions and linked to process crystallisation studies. Both standard and novel particle design strategies will be used to control crystal size and morphology, as well as package the boactive in a deliverable form without loss of activity.Read moreRead less
CHAMP GPS-Altimetry. The proposed research project aims to develop a novel application for the Global Positioning System (GPS), namely the use of GPS signals reflected from sea- or ice-surfaces and received by Low-Earth-Orbiter (LEO) for determination of these surface heights. Data from the German satellite CHAMP will be used for this purpose, for selected regions in Antartica. CHAMP covers areas not visited by other remote sensing satellites. The Fellow is instrumental for obtaining and process ....CHAMP GPS-Altimetry. The proposed research project aims to develop a novel application for the Global Positioning System (GPS), namely the use of GPS signals reflected from sea- or ice-surfaces and received by Low-Earth-Orbiter (LEO) for determination of these surface heights. Data from the German satellite CHAMP will be used for this purpose, for selected regions in Antartica. CHAMP covers areas not visited by other remote sensing satellites. The Fellow is instrumental for obtaining and processing these CHAMP data.
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International Evaluation of Algorithms for Mapping in Optically Shallow Waters. This work provides a means for Australian science and management agencies to apply a method for accurately mapping shallow coastal environments. The work will build Australian research capability by developing new collaborations among experienced researchers; as well as allowing the Australian teams to benchmark their proposed methods internationally. Nationally, the work will strengthen international research exper ....International Evaluation of Algorithms for Mapping in Optically Shallow Waters. This work provides a means for Australian science and management agencies to apply a method for accurately mapping shallow coastal environments. The work will build Australian research capability by developing new collaborations among experienced researchers; as well as allowing the Australian teams to benchmark their proposed methods internationally. Nationally, the work will strengthen international research experience and generate opportunities for postgraduate and postdoctoral researchers to link into leading-edge international research networks. This work will also allow us to build strong ongoing collaborations between research teams in Australia and their counterparts overseas (specifically USA, Canada, UK and Germany). Read moreRead less
Supercomputer Simulation of Multiscale Dynamic Behaviour in Multiphase Deformable Porous Media. This project will establish and consolidate links between leading groups in China and Australia to develop a new and unique multiscale computational model and algorithm for simulating multiphase nonlinear behaviours of the porous media under dynamic loading conditions, and improve technology transfer between the two groups by the mobility of the ARC International Fellow. This will aid Australian geosc ....Supercomputer Simulation of Multiscale Dynamic Behaviour in Multiphase Deformable Porous Media. This project will establish and consolidate links between leading groups in China and Australia to develop a new and unique multiscale computational model and algorithm for simulating multiphase nonlinear behaviours of the porous media under dynamic loading conditions, and improve technology transfer between the two groups by the mobility of the ARC International Fellow. This will aid Australian geoscience and mining industry, such as in HFR geothermal/UCG energy facility design, construction, risk assessment and production and could help Australia shift away from greenhouse gases and become a world leader in the emerging worldwide HFR geothermal/UCG industry.Read moreRead less
Adsorption and recovery of gold thiosulfate using nanoporous carbon. The gold industry is a major export earner for both Australia and the United States. This collaborative project aims to develop an environmentally acceptable, cost effective process for the recovery of gold from thiosulfate leachate. Development of this process will remove one of the barriers to the acceptance of thiosulfate leaching over conventional cyanide extraction, leading to substantial benefits to the gold industry and ....Adsorption and recovery of gold thiosulfate using nanoporous carbon. The gold industry is a major export earner for both Australia and the United States. This collaborative project aims to develop an environmentally acceptable, cost effective process for the recovery of gold from thiosulfate leachate. Development of this process will remove one of the barriers to the acceptance of thiosulfate leaching over conventional cyanide extraction, leading to substantial benefits to the gold industry and the environment. A successful outcome in the research project would also lead to export earnings resulting from technology transfer and an enhanced reputation for high quality research.Read moreRead less