Molecular and immunological approaches to managing Australia's seafood allergy epidemic. Seafood is an increasingly important cause of food allergy. Novel insight into the functions of why and how proteins from seafood develop to potent allergens will lead to the development of better diagnostics and therapeutics. This will assist patients to better manage their serious food allergy.
Development and nutritional evaluation of novel foods based on a unique combination of soy and dairy products. This exciting project will enable us to incorporate two competing food industries (dairy and soy) to develop innovative foods combining soy and low-fat dairy which will provide increased palatability as well as nutrition. This project is a new collaboration between So Natural Foods and the Universities of Wollongong, South Australia and Western Australia. The aims are 1) develop new f ....Development and nutritional evaluation of novel foods based on a unique combination of soy and dairy products. This exciting project will enable us to incorporate two competing food industries (dairy and soy) to develop innovative foods combining soy and low-fat dairy which will provide increased palatability as well as nutrition. This project is a new collaboration between So Natural Foods and the Universities of Wollongong, South Australia and Western Australia. The aims are 1) develop new foods combining soy and low-fat dairy; 2) test the bioavailability of the soy isoflavones (particularly equol production) from these foods; 3) determine the active component(s) in soy (soy protein and/or soy isoflavones) responsible for cholesterol reduction and other health benefits of soy; 4) evaluate consumer acceptability and market potential of the novel soy foods. We expect to demonstrate that healthier and more appealing food products can be produced by combining two currently competing foods, namely soy and dairy.Read moreRead less
A Randomised Controlled Trial To Prevent Eczema, Food Allergy And Sensitisation Using A Skin Barrier Improvement Strategy
Funder
National Health and Medical Research Council
Funding Amount
$878,163.00
Summary
In this world first study, we will test if building the infant skin barrier by using daily regular skin care treatment can reduce the incidence of eczema. If successful, this trial will alter infant skin care practices and reduce the burden of allergic diseases in our community. Furthermore, as infants with eczema having a poor skin barrier, which possibly increases their risk of developing sensitisation, we will test if this intervention reduces the risk of food allergy.
Population-level Vaccine Safety Monitoring: Risk Assessment And Policy Implications
Funder
National Health and Medical Research Council
Funding Amount
$85,649.00
Summary
Vaccines prevent millions of deaths worldwide but events can occur after vaccination which may or may not be related to the vaccine. It is vital to ensure vaccines are safe and that both the public and medical providers remain confident in vaccination programs. The PhD thesis will look at the various methods for monitoring vaccine safety in Australia, and compare the usefulness of each system. This will provide information for policy makers on the safety of vaccines in Australia.
Case-cohort Study Of The Association Between Pertussis Vaccination In Infancy And The Risk Of IgE-mediated Food Allergy.
Funder
National Health and Medical Research Council
Funding Amount
$144,742.00
Summary
Allergic diseases are one of the most important causes of chronic morbidity among children in Australia. This is a retrospective case-controlled trial, utilising data from the Australian immunisation register and cases of confirmed food allergy, to examine the role of vaccination in protection against food allergy. If a relationship between the type of vaccination and protection against allergy is found, this would have implications for allergy prevention and immunisation policy.
BCG Immunisation To Prevent Allergy In Children: An Intervention Trial
Funder
National Health and Medical Research Council
Funding Amount
$1,187,260.00
Summary
There has been a dramatic rise in allergic diseases (asthma, eczema, food allergy) worldwide and particularly in Australia, with up to 30% of children affected. There is evidence from small studies that BCG immunisation has beneficial effects that prevent an allergic type immune response later in life. In a large randomised trial we will determine whether BCG at birth prevents allergic disease by monitoring eczema and food sensitivity in infancy, both of which predict an allergic predisposition.
Brief naps as a countermeasure to fatigue. The proposed research will be necessary in order to identify the best length of nap to reduce fatigue both in the afternoon and in the early morning hours. It may also discover that naps of certain lengths may impair performance and safety under some conditions. Thus the proposed research is crucial in order to develop a non-drug countermeasure for fatigue in conditions of impaired performance and safety. Therefore, it will play an important occupati ....Brief naps as a countermeasure to fatigue. The proposed research will be necessary in order to identify the best length of nap to reduce fatigue both in the afternoon and in the early morning hours. It may also discover that naps of certain lengths may impair performance and safety under some conditions. Thus the proposed research is crucial in order to develop a non-drug countermeasure for fatigue in conditions of impaired performance and safety. Therefore, it will play an important occupational health and safety role on the job in the afternoon day shift and the early morning during night shift work.. Furthermore, it will improve general quality and productivity of life in a culture of increasing fatigue.Read moreRead less
Applied Research In The Prevention And Control Of Infections In The Hospital Setting
Funder
National Health and Medical Research Council
Funding Amount
$174,434.00
Summary
Hospital infections result in increased: (1) length of stay; (2) costs to the healthcare system and individual and (3) morbidity/mortality. Vaccination and hand hygiene are both proven infection control practices. However, compliance rates are still less than ideal. I will study how a new innovative method impacts on uptake of both. Barriers to masks as an infection control strategy will also be examined, as they are one of the few strategies that can be guaranteed to be available in a pandemic.
Effectiveness and appropriateness of child restraints. This project aims to provide a definitive picture of the use, misuse and inappropriate use of child restraints in motor vehicles. It will evaluate the biomechanical and size deficiencies of current child restraints for the current population of children, and the implications for increased injury associated with these factors. This will provide a solid evidence base for improved child restraint design, education, and legislative changes.
Development and evaulation of novel foods enriched with very long chain omega-3 fatty acids. This project is a collaborative effort between Meadow Lea Foods, Clover Corporation, and the Universities of Wollongong and Western Australia. The aims are 1) to develop a range of functional foods enriched with omega-3 from tuna oil; 2) to see whether the recommended omega-3 intake, currently nor met by most Australians, can be achieved by including these foods in the diet; 3) to evaluate sensory and he ....Development and evaulation of novel foods enriched with very long chain omega-3 fatty acids. This project is a collaborative effort between Meadow Lea Foods, Clover Corporation, and the Universities of Wollongong and Western Australia. The aims are 1) to develop a range of functional foods enriched with omega-3 from tuna oil; 2) to see whether the recommended omega-3 intake, currently nor met by most Australians, can be achieved by including these foods in the diet; 3) to evaluate sensory and health attributes and other factors that may impact on consumer acceptability hence market potential of the food range. There is little evidence of the feasibility let alone health and social benefits of utilising novel foods to meet the dietary omega-3 recommendation. We expect a) to show how consumers could benefit by using a range of such foods in their customary diet; b) to critically set this achievement within the context of current social trends in food product development. Read moreRead less