Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by ....Mitigating the Severity of Level Crossing Accidents and Derailments. Ongoing increases in the number of level crossings and heavy road vehicles cause more frequent and severe level crossing accidents and derailments. Despite the use of active warning systems, each year, on average, 100 level crossing accidents occur in Australia. With a view to mitigating these crashes, this research aims to formulate theories for reduction in crash energy and effective wheel constraints to prevent derailment by modifying the levels of road and rail crossings and providing guard rails in the recesses of these modified level crossings. The theories are intended be developed using nonlinear dynamic computational methods and laboratory experiments. The outcomes are expected to enable reduction in the severity of level crossing accidents and hence save lives and costs of derailment.Read moreRead less
Radiation and Ablation in Rapidly Expanding Flows. The aim of the project is to record the spectra of radiation from a region of rapidly expanding flow representative of the passage of the shock layer on a re-entry capsule from the windward to the leeward surfaces. The significance of this work is that it addresses a critical area of spacecraft where the uncertainties of our design techniques are of the order of 300 per cent in terms of surface heat transfer, and current vehicles have to use lar ....Radiation and Ablation in Rapidly Expanding Flows. The aim of the project is to record the spectra of radiation from a region of rapidly expanding flow representative of the passage of the shock layer on a re-entry capsule from the windward to the leeward surfaces. The significance of this work is that it addresses a critical area of spacecraft where the uncertainties of our design techniques are of the order of 300 per cent in terms of surface heat transfer, and current vehicles have to use large safety factors to ensure survivability. The outputs from the project will be a data base of radiative parameters which should enable accurate models of the flow to be developed, which is expected to facilitate the design of advanced spacecraft with greater safety and reliability, and with lower structural mass.Read moreRead less
Engineering a nanovaccine for cost-effective influenza poultry vaccination. The project aims to develop a new single-dose, room temperature-stable nanovaccine for cost-effective influenza poultry vaccination. The nanovaccine is based on viral protein assembly modularised to present multiple copies of influenza antigen. Particularly, this project focuses on the engineering of this vaccine manufacturing and formulation for a room temperature-stable vaccine. The resulting engineered vaccine would p ....Engineering a nanovaccine for cost-effective influenza poultry vaccination. The project aims to develop a new single-dose, room temperature-stable nanovaccine for cost-effective influenza poultry vaccination. The nanovaccine is based on viral protein assembly modularised to present multiple copies of influenza antigen. Particularly, this project focuses on the engineering of this vaccine manufacturing and formulation for a room temperature-stable vaccine. The resulting engineered vaccine would play an important role in preventing avian influenza outbreaks, which are currently affecting both developed and developing countries, costing millions of dollars due to the death and culling of infected poultry.Read moreRead less
Emotions and Employee Turnover: New Methods for Complex Dynamic Systems. This project aims to vastly improve the data-analytic capabilities of social and health researchers, while increasing knowledge about emotion dynamics and their link to employee turnover. By drawing on and advancing methods from ecology and applied physics, this project plans to investigate the role that individual emotions play in employee turnover with new quantitative methods for characterising and testing causality in c ....Emotions and Employee Turnover: New Methods for Complex Dynamic Systems. This project aims to vastly improve the data-analytic capabilities of social and health researchers, while increasing knowledge about emotion dynamics and their link to employee turnover. By drawing on and advancing methods from ecology and applied physics, this project plans to investigate the role that individual emotions play in employee turnover with new quantitative methods for characterising and testing causality in complex dynamic systems. The expected outcomes include an improved capacity for researchers, managers, and policy makers to understand complex organisational, economic, and health systems. This will provide immediate societal benefits by informing the development and deployment of targeted interventions in such systems.Read moreRead less
Protein Structure and Dynamics by Electron/Nuclear Paramagnetic Resonance. This interdisciplinary project aims to establish new magnetic resonance methods for the analysis of protein structure and motion at low concentrations and in physiological conditions that are otherwise difficult or impossible to study. It brings together four different research groups with expertise in advanced biochemistry, modern magnetic spectroscopy and high-performance computing. The project expects to develop tools ....Protein Structure and Dynamics by Electron/Nuclear Paramagnetic Resonance. This interdisciplinary project aims to establish new magnetic resonance methods for the analysis of protein structure and motion at low concentrations and in physiological conditions that are otherwise difficult or impossible to study. It brings together four different research groups with expertise in advanced biochemistry, modern magnetic spectroscopy and high-performance computing. The project expects to develop tools to study protein structure, protein-protein association and protein-ligand interactions of established drug-targets. Expected outcomes include new techniques that quickly inform how drugs work, providing significant benefits to many researchers studying biomolecules, and supporting Australia’s growing biotechnology sector. Read moreRead less
Understanding dissipation, thermal conduction and diffusion in superionic conductors using ab initio nonequilibrium molecular dynamics simulation. Lithium ion batteries are widely used in computers, cars and more recently in aircraft. However they may exhibit thermal runaway leading to fire. Recently these problems have grounded the fleet of Boeing 787 aircraft, worldwide. Understanding superionic conduction is of thus of considerable technological importance. The project will focus on understa ....Understanding dissipation, thermal conduction and diffusion in superionic conductors using ab initio nonequilibrium molecular dynamics simulation. Lithium ion batteries are widely used in computers, cars and more recently in aircraft. However they may exhibit thermal runaway leading to fire. Recently these problems have grounded the fleet of Boeing 787 aircraft, worldwide. Understanding superionic conduction is of thus of considerable technological importance. The project will focus on understanding mass and heat flow in superionic conductors using a new molecular simulation technique that the team has recently developed. This technique combines nonequilibrium statistical mechanics and ab initio molecular dynamics simulation. The project will learn how heat is generated and conducted through these materials and how temperature influences these processes, and how heat and mass flow couple together.Read moreRead less
Architectural design to improve Indigenous health outcomes. The project seeks to develop evidence-based knowledge on what Indigenous clients find supportive or stressful in health care settings, to formulate recommendations for architectural design and service delivery. Many Indigenous people fail to present for health care until chronically ill, due to fear or dislike of health services and their settings. This project aims to understand how design in healthcare architecture across different bu ....Architectural design to improve Indigenous health outcomes. The project seeks to develop evidence-based knowledge on what Indigenous clients find supportive or stressful in health care settings, to formulate recommendations for architectural design and service delivery. Many Indigenous people fail to present for health care until chronically ill, due to fear or dislike of health services and their settings. This project aims to understand how design in healthcare architecture across different building scales and services (clinics, hospitals, waiting rooms, wards etc) affects Indigenous people’s use and perceptions of these environments and consequent motivation to access health care services. Developing innovative and adaptable research methods, the project seeks to identify the necessary architectural design changes for health settings to facilitate access for Indigenous people.Read moreRead less