Investigation Of The Molecular Basis Of Frailty And Development Of Frailty Biomarkers In A Novel Mouse Ageing Model
Funder
National Health and Medical Research Council
Funding Amount
$408,768.00
Summary
Frailty is a state of high vulnerability for adverse health outcomes, and the prevalence of frailty increases with increasing age. There is very little known about why frailty develops, and there is also no widely accepted, efficient method of determining if someone is frail. This project will test blood markers for frailty, that will allow for optimization of treatment for older frail people and use mouse models of frailty to learn more about why frailty develops.
Understanding Frailty In Older People: An Epidemiological Insight
Funder
National Health and Medical Research Council
Funding Amount
$314,644.00
Summary
We need to find better and more efficient ways to identify older people at risk of poor outcomes. The measurement of frailty, a key concept in geriatric medicine, may provide this exact information. The proposed research will investigate frailty in large-scale population datasets across both community and hospital settings. Results can be used to guide patient management, influence public health policy and inform future intervention studies.
Brain Ageing – Understanding The Relationships Between Brain Structure, Gait, Cognition And Falls
Funder
National Health and Medical Research Council
Funding Amount
$184,768.00
Summary
This fellowship will support novel population-based research directed at understanding how the ageing brain is associated with cognition and the control of gait in older people, and whether early gait changes are able to predict serious adverse outcomes such as future dementia and falls. A better understanding of the relationship between the brain, cognition and mobility is crucial in the step towards successful ageing of older Australians.