Evolutionary history and impact of adeno-associated viruses in Australia. Recently accrued evidence identifies Australia as an ideal closed-model system in which to elucidate the evolutionary history of a group of non-pathogenic viruses, known as adeno-associated viruses (AAVs). This project aims to trace back the evolutionary history of AAVs for tens of millions of years via molecular fossil imprints left behind by ancient viral invasions of Australian marsupial genomes. Concurrently, the poten ....Evolutionary history and impact of adeno-associated viruses in Australia. Recently accrued evidence identifies Australia as an ideal closed-model system in which to elucidate the evolutionary history of a group of non-pathogenic viruses, known as adeno-associated viruses (AAVs). This project aims to trace back the evolutionary history of AAVs for tens of millions of years via molecular fossil imprints left behind by ancient viral invasions of Australian marsupial genomes. Concurrently, the potential impact that these viral invasions had on the evolutionary development of their ancestral hosts will be investigated. This could facilitate previously unattainable insights into both AAV and marsupial evolution, with broader implications relevant to the advancement of the fields of virology and mammalian evolution.Read moreRead less
Will genetic rescue save the Tasmanian devil? This project aims to measure the long-term genetic impacts of the Save the Tasmanian Devil Program’s ‘Wild Devil Recovery’ initiative. The project will determine whether supplementing small populations with individuals that are genetically diverse reduces inbreeding depression. The project will also monitor the impact of supplementation on the evolutionary trajectory of Devil Facial Tumour Disease. The project will train a cohort of conservation scie ....Will genetic rescue save the Tasmanian devil? This project aims to measure the long-term genetic impacts of the Save the Tasmanian Devil Program’s ‘Wild Devil Recovery’ initiative. The project will determine whether supplementing small populations with individuals that are genetically diverse reduces inbreeding depression. The project will also monitor the impact of supplementation on the evolutionary trajectory of Devil Facial Tumour Disease. The project will train a cohort of conservation scientists to translate genetic data into management actions. The outputs will directly inform the management actions of the Tasmanian Department of Primary Industries Parks, Water and the Environment and will help shape other species recovery programs.Read moreRead less
The pull-out capacity of a newly developed grouted soil nailing system. The project aims to develop a new reliable and efficient grouted soil nail system for improving the performance of loose soft soils. Important applications of the research include the mitigation of landslides, which pose a major threat to communities and infrastructure worldwide. Laboratory small scale experiments and numerical analyses will be carried out to optimize the grouting efficiency and enhance the pull-out resistan ....The pull-out capacity of a newly developed grouted soil nailing system. The project aims to develop a new reliable and efficient grouted soil nail system for improving the performance of loose soft soils. Important applications of the research include the mitigation of landslides, which pose a major threat to communities and infrastructure worldwide. Laboratory small scale experiments and numerical analyses will be carried out to optimize the grouting efficiency and enhance the pull-out resistance between the grout and surrounded soil in the soil nail system. This integrated project will provide a valuable tool for engineers who wish to stabilize loose fill slopes or soft grounds in Australia and worldwide.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE0561251
Funder
Australian Research Council
Funding Amount
$150,887.00
Summary
Facility for Analyses of Evolutionary Immunology. Our understanding of how selection in natural populations shape (favour and disfavour) immunity, and how this process contribute to organismal (including human) fitness, is rudimentary. In order to study such processes our collective experience strongly suggests and increasing need for geographic amalgamation of necessary and complementary molecular and biomedical techniques. We therefore request funding to establish a collaborative research labo ....Facility for Analyses of Evolutionary Immunology. Our understanding of how selection in natural populations shape (favour and disfavour) immunity, and how this process contribute to organismal (including human) fitness, is rudimentary. In order to study such processes our collective experience strongly suggests and increasing need for geographic amalgamation of necessary and complementary molecular and biomedical techniques. We therefore request funding to establish a collaborative research laboratory in a novel research field - Evolutionary Immuno-Ecology- in which all vital aspects, from a mechanistic to an evolutionary level, can be studied at one research centre.Read moreRead less
Early Career Industry Fellowships - Grant ID: IE230100048
Funder
Australian Research Council
Funding Amount
$466,097.00
Summary
Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway ....Ammonium-selective membranes to shift water industry into circular economy. The project aims to develop ammonium-selective membranes which are urgently needed in Australian key industries for sustainable ammonia recovery. The project expects to construct the membranes to achieve desirable pore size and surface functionality for fast and selective ammonia transport. The developed membranes should make ammonia recovery from wastewater more effective and sustainable, leading to the healthy waterway and reduced energy for both ammonia production and removal. Recovered ammonia expects to produce valuable products, supporting agriculture industry and hydrogen economy. The developed membranes should enable water industry's shift into circular economy, providing significant economic and environmental benefits to Australia.Read moreRead less
Marine vessel wave wake: Ferry operations in sheltered waterways. This project aims to address one of the biggest risk factors to the Sydney ferry system, by ensuring the waves that new ferries generate are minimised. This would reduce the impact on other users of this busy waterway or damage to the surrounding infrastructure or environment. Modernising Sydney’s fleet of iconic passenger ferries is an integral part of the New South Wales Government’s long-term transport master plan. The project ....Marine vessel wave wake: Ferry operations in sheltered waterways. This project aims to address one of the biggest risk factors to the Sydney ferry system, by ensuring the waves that new ferries generate are minimised. This would reduce the impact on other users of this busy waterway or damage to the surrounding infrastructure or environment. Modernising Sydney’s fleet of iconic passenger ferries is an integral part of the New South Wales Government’s long-term transport master plan. The project is intended to predict the waves produced by any proposed ferry operation, allowing changes to be made to minimise waves during early planning stages. The new method for predicting the complex wave phenomenon is designed to provide more comprehensive and accurate assessments than conventional technologies.Read moreRead less
Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategi ....Optimising Control of Hydroelectric Turbines Subject to Basslink Instability. With the introduction of Basslink, an underwater DC power cable across the Bass Strait, Tasmania will be connected to the national Electricity Market. Basslink will also provide an opportunity to utilise the significant water energy potential found throughout Tasmania. This project will examine the impact and disturbances due to the connection of Basslink with Tasmanian hydro power systems and develop control strategies for effective operation and control of hydro turbines with Basslink. Particular attention will be paid to the quality and reliability of electricity supply in Tasmania.Read moreRead less
Lamarckian lizards: novel integration of telomere epigenetics, free radicals and innate antioxidants in condition-dependant sexual signal evolution. In 2009, the Nobel Prize in physiology was awarded Drs. Blackburn, Greider and Szostak for discoveries on telomeres. This project will investigate how telomeres not only cap chromosomes from destruction by free radicals, but also have a key role in life itself, in their influence on ageing, longevity, ornaments and lifetime reproductive success.