Socio-spatial implications of smart city development in India. The project aims to generate extensive new knowledge on the complex socio-spatial implications of smart city development; and the ways in which they have been further consolidated, expedited, and elevated in response to COVID, and to stimulate the pandemic-hit economies. It makes a significant contribution to smart urbanism discourse globally with a focus on equity and its special role at times of crisis. The outcomes include a Smart ....Socio-spatial implications of smart city development in India. The project aims to generate extensive new knowledge on the complex socio-spatial implications of smart city development; and the ways in which they have been further consolidated, expedited, and elevated in response to COVID, and to stimulate the pandemic-hit economies. It makes a significant contribution to smart urbanism discourse globally with a focus on equity and its special role at times of crisis. The outcomes include a Smart City Roadmap for advising diverse stakeholders on how to negotiate for and build inclusive smart cities - with significant benefits in strengthening existing, and building new connections between India and Australia in an area of bilateral national significance.Read moreRead less
Transforming tobacco policy to deliver societal benefits. This project aims to develop new regulatory options for tobacco to minimise the legal market while avoiding the adverse societal and economic impacts of transferring consumer demand to illegal tobacco products. It addresses a significant current concern about a growing illegal tobacco market and seeks to improve understanding of the impact of tobacco control policies on the illegal market, and the societal impacts. The project also seeks ....Transforming tobacco policy to deliver societal benefits. This project aims to develop new regulatory options for tobacco to minimise the legal market while avoiding the adverse societal and economic impacts of transferring consumer demand to illegal tobacco products. It addresses a significant current concern about a growing illegal tobacco market and seeks to improve understanding of the impact of tobacco control policies on the illegal market, and the societal impacts. The project also seeks to draw insights from illicit drug policy to understand potential consequences of greater restrictions on the legal tobacco market. The expected outcomes include an enhanced monitoring system for illicit tobacco and policy recommendations to achieve government goals of reducing smoking rates.Read moreRead less
Regularisation methods of inverse problems: theory and computation. This project aims to investigate regularisation methods for inverse problems which are ill-posed in the sense that their solutions depend discontinuously on the data. When only noisy data is available, regularisation methods define stable approximate solutions by replacing the original inverse problem with a family of well-posed neighbouring problems monitored by a so-called regularisation parameter. The project expects to devel ....Regularisation methods of inverse problems: theory and computation. This project aims to investigate regularisation methods for inverse problems which are ill-posed in the sense that their solutions depend discontinuously on the data. When only noisy data is available, regularisation methods define stable approximate solutions by replacing the original inverse problem with a family of well-posed neighbouring problems monitored by a so-called regularisation parameter. The project expects to develop purely data-driven rules to choose the regularisation parameter and show how they work in theory, and in practice. It will also develop convex framework, acceleration strategies as well as preconditioning and splitting ideas to design efficient regularisation solvers.Read moreRead less
Partial differential equation: Schrodinger operator and long-time dynamics. This project aims to develop new analysis methods associated to the Schrodinger operator, and to solve several challenging problems regarding dispersive partial differential equations (PDE). Long-time dynamics of PDE solutions are a key goal in both pure and applied mathematics, and have been extensively studied by leading mathematicians and mathematical physicists. However, it is unknown how to investigate large soluti .... Partial differential equation: Schrodinger operator and long-time dynamics. This project aims to develop new analysis methods associated to the Schrodinger operator, and to solve several challenging problems regarding dispersive partial differential equations (PDE). Long-time dynamics of PDE solutions are a key goal in both pure and applied mathematics, and have been extensively studied by leading mathematicians and mathematical physicists. However, it is unknown how to investigate large solutions when the order of the PDE's nonlinearity is low. This project expects to develop new methods to attack such problems. The results of the project will be of great importance in mathematics and physics, as many fundamental physical models in areas such as optics, fluid mechanics and quantum mechanics fit the paradigm.Read moreRead less
Problems in harmonic analysis: decoupling and Bourgain-Brezis inequalities. This project in mathematics aims to study two recent, promising developments in harmonic analysis, namely Fourier decoupling and Bourgain-Brezis inequalities. The former captures how waves interfere upon superposition; the latter arose initially in the study of the Ginzburg-Landau theory of superconductors. This exciting project seeks to deliver deep insights into how different frequencies interact, and aims to develop p ....Problems in harmonic analysis: decoupling and Bourgain-Brezis inequalities. This project in mathematics aims to study two recent, promising developments in harmonic analysis, namely Fourier decoupling and Bourgain-Brezis inequalities. The former captures how waves interfere upon superposition; the latter arose initially in the study of the Ginzburg-Landau theory of superconductors. This exciting project seeks to deliver deep insights into how different frequencies interact, and aims to develop powerful new tools to advance the study of partial differential equations and analytic number theory. This Future Fellowship should benefit Australia by improving our scientific capability. It will bring world-class researchers to Australia for collaboration, and put Australia at the forefront of first rate research.
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Everyday autism: bridging the gap between lab and life. Recent research demonstrates that autistic people, their families and professionals often feel that there remains a sharp divide between autism science and key aspects of everyday autistic life, despite significant public investment in that science. This proposed research investigates reasons for this divide and proposes ways in which it might be overcome. Expected outcomes include greater opportunities for autistic people to play active ro ....Everyday autism: bridging the gap between lab and life. Recent research demonstrates that autistic people, their families and professionals often feel that there remains a sharp divide between autism science and key aspects of everyday autistic life, despite significant public investment in that science. This proposed research investigates reasons for this divide and proposes ways in which it might be overcome. Expected outcomes include greater opportunities for autistic people to play active roles in the research process and more scientific experimentation that moves out of the laboratory and into more true-to-life settings. Bridging the gap between lab and life will result in better theory-building on autism, better translation of scientific discoveries and more robust policy recommendations.Read moreRead less
A Bayesian Approach to Distributed Estimation for Multi-Object Systems. This project aims to develop new signal processing techniques that facilitate autonomous technologies for environmental perception, with the ability to efficiently process large data volumes from multiple sensing modalities. Rapid advances in sensors and networks have led to a digital data deluge, from which extracting useful information presents new technological challenges and opportunities. To address this development, th ....A Bayesian Approach to Distributed Estimation for Multi-Object Systems. This project aims to develop new signal processing techniques that facilitate autonomous technologies for environmental perception, with the ability to efficiently process large data volumes from multiple sensing modalities. Rapid advances in sensors and networks have led to a digital data deluge, from which extracting useful information presents new technological challenges and opportunities. To address this development, this project seeks to develop new distributed solutions for statistical estimation, which are specifically designed for dynamic systems with multiple object states, and are inherently scalable and robust. The potential benefits include new technologies for smart cities, autonomous infrastructure, and digital productivity.Read moreRead less
The role of genome reorganisation in adaptation and speciation. Local adaptation and speciation are fundamental evolutionary processes that rely on changes to the genome. However, the role of genome architecture (e.g. chromosomal rearrangements, gene duplications) in driving these processes is poorly understood. This project will use advanced comparative genomics and bioinformatics to examine the role of chromosome rearrangements in driving adaptation and speciation, and evaluate rates of molec ....The role of genome reorganisation in adaptation and speciation. Local adaptation and speciation are fundamental evolutionary processes that rely on changes to the genome. However, the role of genome architecture (e.g. chromosomal rearrangements, gene duplications) in driving these processes is poorly understood. This project will use advanced comparative genomics and bioinformatics to examine the role of chromosome rearrangements in driving adaptation and speciation, and evaluate rates of molecular evolution between the X-chromosome and autosomes. Utilising Australia’s endemic mammalian fauna as a tractable model system, I will link population processes with macro-evolutionary outcomes to show how genome architecture underpins biodiversity.Read moreRead less
Hidden complexity in microRNA function. This project aims to determine the extent to which microRNAs function through “non-canonical” mechanisms within cell nuclei, how their roles are expanded by naturally occurring sequence variation and how their activity is controlled by little known families of genes that sequester and inhibit their availability. The knowledge generated is significant as microRNAs regulate the expression of virtually all genes and biological processes, yet these mechanisms ....Hidden complexity in microRNA function. This project aims to determine the extent to which microRNAs function through “non-canonical” mechanisms within cell nuclei, how their roles are expanded by naturally occurring sequence variation and how their activity is controlled by little known families of genes that sequester and inhibit their availability. The knowledge generated is significant as microRNAs regulate the expression of virtually all genes and biological processes, yet these mechanisms of function remain poorly characterised and seldom considered. The expected outcome of better understanding mechanisms through which microRNAs work should provide significant benefit to safe and effective development of microRNAs for future agricultural or therapeutic application.Read moreRead less
Metabolic control of gene expression networks and microbiome interactions. The proposal aims to advance our understanding of how metabolism (and resulting metabolites) regulate the expression of genes, and investigate how these processes dictate the interaction of microbiota with the immune system. The project is expected to generate transformative knowledge of gene regulation, a fundamental process for cellular function, and decipher how the microbiome yeast Candida albicans interacts with immu ....Metabolic control of gene expression networks and microbiome interactions. The proposal aims to advance our understanding of how metabolism (and resulting metabolites) regulate the expression of genes, and investigate how these processes dictate the interaction of microbiota with the immune system. The project is expected to generate transformative knowledge of gene regulation, a fundamental process for cellular function, and decipher how the microbiome yeast Candida albicans interacts with immune cells and bacteria. By utilising a powerful combination of molecular and systems biology with molecular genetics and imaging, the project outcomes should foster interdisciplinary collaborations and build capacity for fundamental and applied research to benefit academia and industry, locally and globally.Read moreRead less