Immediate Or Delayed Cord Clamping In The Preterm Birth Transition: Is There A Trade-off Between Circulatory Stability And Sympathoadrenal Activation?
Funder
National Health and Medical Research Council
Funding Amount
$824,582.00
Summary
Using an established experimental model of preterm birth, this project will determine if delayed clamping of the umbilical cord at birth leads to better stability of the circulation than immediate clamping, and if this improved stability comes at a cost of not activating the involuntary nervous system essential for enhancing metabolic and lung function after birth. The results of this study will provide fundamental new information for optimizing birth delivery strategies in preterm babies.
Novel Therapy For Heart Failure With Preserved Ejection Fraction
Funder
National Health and Medical Research Council
Funding Amount
$1,068,984.00
Summary
Heart failure is a major cardiovascular problem. Up to half of the patients have a specific problem with heart muscle relaxation. There is no effective therapy for this type of heart failure. We will investigate the effects of new treatment approach using a range of experimental and clinical methods. If successful the treatment could move quickly into clinical practice.
Reducing Morbidities In Preterm Growth Restricted Neonates.
Funder
National Health and Medical Research Council
Funding Amount
$687,214.00
Summary
Intrauterine growth restriction (IUGR) is a serious complication of pregnancy and occurs when fetal growth is abnormal, resulting in a fetus that is smaller than it should be for its given gestational age. IUGR babies are at much greater risk of many short and long-term adverse outcomes. This study investigates the role that adverse cardiovascular development plays in the progression of lung, heart and brain disease in preterm IUGR newborns.