Understanding and controlling bioavailability: passive dosing of persistent organic pollutants into recombinant cell bioassays. Bioassays with mammalian cell lines may replace animal testing in chemical risk assessment if issues with limited sensitivity can be overcome for very hydrophobic chemicals such as polychlorinated dibenzodioxins. The project will solve this problem by developing a polymer-release dosing technique that assures defined and constant exposure.
A novel path to environmental and human health risk assessment of transformation products. Chemical pollution is a threat to our rivers and drinking water supplies. Degradation during water treatment and in the environment may lead to persistent and toxic transformation products. This project will provide a practical and cost-efficient risk assessment strategy for transformation products - to help ensure that our drinking water is safe.
Fate of micropollutants in water recycling: influence of dissolved organic matter. Access to safe drinking water is essential for the economic and social development of Australia. There is increasing interest in applying advanced water treatment processes, such as membrane filtration or ozonation, to treat secondary effluent to a potable standard. This project promotes improved organic pollutant removal and monitoring during advanced water treatment and will contribute to the National Research P ....Fate of micropollutants in water recycling: influence of dissolved organic matter. Access to safe drinking water is essential for the economic and social development of Australia. There is increasing interest in applying advanced water treatment processes, such as membrane filtration or ozonation, to treat secondary effluent to a potable standard. This project promotes improved organic pollutant removal and monitoring during advanced water treatment and will contribute to the National Research Priority goal, water - a critical resource, by providing the increased protection of receiving waters including rivers and seawater. Further, as very few studies consider the role of dissolved organic matter for organic pollutant fate in water reuse internationally, this project will help to advance Australia's position in science.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE210100137
Funder
Australian Research Council
Funding Amount
$881,758.00
Summary
Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-fun ....Australian Environmental Specimen Bank: advancing specimen bank capability. The aim of this LIEF is to advance Australia’s specimen banking capabilities through a new, enhanced national facility, the Australian Environmental Specimen Bank (AESB). The AESB would be founded on a unique current archive of human and environmental samples established by the partners to the LIEF. Importantly, the AESB would be managed as a nationally available (to all public sector researchers), operationally self-funded resource for integrated exposure research into the future. The archive is expected to support longitudinal and cross-sectional studies to assess trends in exposure to chemical and biological hazards in the Australian population, identify emerging hazards, and provide a scientific basis for policy and regulatory actions.Read moreRead less
Understanding third hand exposure of Australian people to methamphetamine. In Australia, there is high community concern around inadvertent exposure to methamphetamine residues in contaminated houses. In this proposal, an interdisciplinary research team aim to engage with public health authorities and public housing industry to conduct collaborative research on total exposure to methamphetamine in contaminated indoor environments. The project will assess exposure pathways (via air, dust, surface ....Understanding third hand exposure of Australian people to methamphetamine. In Australia, there is high community concern around inadvertent exposure to methamphetamine residues in contaminated houses. In this proposal, an interdisciplinary research team aim to engage with public health authorities and public housing industry to conduct collaborative research on total exposure to methamphetamine in contaminated indoor environments. The project will assess exposure pathways (via air, dust, surfaces) and link them with methamphetamine levels in samples from occupants (urine, hair). The project is expected to significantly enhance our understanding of how third hand exposure leads to internal exposure in humans. This knowledge provides evidence for policies on residential indoor exposures and remediation strategies.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE120100161
Funder
Australian Research Council
Funding Amount
$375,000.00
Summary
Accumulation and half-lives of brominated flame retardants. This project seeks to determine, in vivo, previously unknown half-lives for brominated flame retardants, chemicals used in numerous, everyday products. This is vital for predicting the duration of human contamination with these persistent, toxic, bioaccumulative chemicals and assessing effectiveness of legislation to reduce human exposure.
Reducing glyphosate exposure from high use practices. This project aims to investigate methods of reducing occupational exposure to glyphosate, a ubiquitous pollutant of emerging concern. This will be achieved through developing new cost-effective analytical and sampling tools and refining methods for integrating human exposure (biomonitoring) data with surveillance data on the pathways of glyphosate exposure from high use. The project will generate new targeted knowledge on (sub) population-spe ....Reducing glyphosate exposure from high use practices. This project aims to investigate methods of reducing occupational exposure to glyphosate, a ubiquitous pollutant of emerging concern. This will be achieved through developing new cost-effective analytical and sampling tools and refining methods for integrating human exposure (biomonitoring) data with surveillance data on the pathways of glyphosate exposure from high use. The project will generate new targeted knowledge on (sub) population-specific chemical exposures in Australia, and globally. Such data are critical to inform public health and chemical regulation policy, and provide clear guidance aimed at reducing exposures, to assess the effectiveness of existing regulations, and provide a framework for implementing surveys in the future.Read moreRead less
Revolutionising water-quality monitoring in the information age. In today’s information age, automated low-cost sensors distributed in the environment have the potential to revolutionise the way we monitor and manage air, water and soil. This project aims to develop novel statistical methods to detect anomalies in the data generated from these in-situ sensors with computationally efficient modelling on river networks through space and time, with the applied goals of automating anomaly detection ....Revolutionising water-quality monitoring in the information age. In today’s information age, automated low-cost sensors distributed in the environment have the potential to revolutionise the way we monitor and manage air, water and soil. This project aims to develop novel statistical methods to detect anomalies in the data generated from these in-situ sensors with computationally efficient modelling on river networks through space and time, with the applied goals of automating anomaly detection in water-quality data and generating predictions of sediment and nutrient concentrations throughout river networks in near-real time. This will represent a fundamental increase in scientific knowledge, which will be immediately useful in the domains of aquatic science, environmental monitoring, and statistics.Read moreRead less
Australian Laureate Fellowships - Grant ID: FL200100028
Funder
Australian Research Council
Funding Amount
$2,854,682.00
Summary
Transforming our understanding of the chemical exposome. Despite many benefits associated with the use of chemicals, there is consensus that their accelerated production and use is increasingly affecting environmental health. Effective tools to understand spatiotemporal trends and factors that drive chemical exposure are urgently needed. This project aims to develop these tools by combining established programs in systematic sampling and archiving with advanced informatics and analytical techniq ....Transforming our understanding of the chemical exposome. Despite many benefits associated with the use of chemicals, there is consensus that their accelerated production and use is increasingly affecting environmental health. Effective tools to understand spatiotemporal trends and factors that drive chemical exposure are urgently needed. This project aims to develop these tools by combining established programs in systematic sampling and archiving with advanced informatics and analytical techniques. The project expects to identify emerging chemicals of concern, assess factors that affect exposure and model exposure based on chemical production, use and fate. Outcomes will support evidence-based regulation and management of chemicals to minimise adverse impacts of chemical exposure in Australia.Read moreRead less
Understanding changes in chemical exposure through integrative sampling and systematic archiving. Poor data on exposure limits our understanding of the effects of chemical exposure on health. This project will aim to develop population-based exposure monitoring strategies to measure exposure, exposure trends, the success of intervention strategies and associations between exposure and health outcomes.