Economic impacts of disease on older workers: Costs to government and individuals and opportunities for intervention. With an ageing workforce, Australia is at risk of having an inadequate workforce to ensure economic growth and to maintain sufficient taxation revenue to support future needs.
This project will provide fill substantial gaps in the Australian evidence the health conditions that keep older workers out of the labour market and that diminish their own immediate and long-term livi ....Economic impacts of disease on older workers: Costs to government and individuals and opportunities for intervention. With an ageing workforce, Australia is at risk of having an inadequate workforce to ensure economic growth and to maintain sufficient taxation revenue to support future needs.
This project will provide fill substantial gaps in the Australian evidence the health conditions that keep older workers out of the labour market and that diminish their own immediate and long-term livings standards and reduce funds available to government. We will address one of the most significant issues resulting fundamental changes to the demography of the Australian labour market and one is regularly raised by the Prime Minister and Treasurer in their speeches following the Intergenerational Report.Read moreRead less
Boosting organ donation registration in diverse communities. This project aims to increase the number and diversity of people on the Australian Organ Donor Register. Transplant success can increase when organs are matched between people of similar ethnic backgrounds, but diverse communities have historically low registration rates. This project is significant because it focuses on this disparity to co-create with two diverse communities interactive media and community dissemination strategies th ....Boosting organ donation registration in diverse communities. This project aims to increase the number and diversity of people on the Australian Organ Donor Register. Transplant success can increase when organs are matched between people of similar ethnic backgrounds, but diverse communities have historically low registration rates. This project is significant because it focuses on this disparity to co-create with two diverse communities interactive media and community dissemination strategies that respect cultural and religious beliefs while addressing concerns about donation raised in our previous research. Tested with a third diverse community, the outcome will be a model that can be both scaled and tailored to ensure equitable access to transplantation for all, benefiting the lives of many. Read moreRead less
Social Impact and Connection Outcomes Associated with Community Sport. Outcomes of social connection from community sport are widely touted and supported to exist. However, we know little about how social infrastructure actually delivers these benefits. It is difficult to understand and develop practices that organisations can use to maximise the outcomes of sport participation. This research aims to investigate how social infrastructure delivers social connection outcomes associated with commun ....Social Impact and Connection Outcomes Associated with Community Sport. Outcomes of social connection from community sport are widely touted and supported to exist. However, we know little about how social infrastructure actually delivers these benefits. It is difficult to understand and develop practices that organisations can use to maximise the outcomes of sport participation. This research aims to investigate how social infrastructure delivers social connection outcomes associated with community sport. Expected outcomes include novel practice based tools and guidance for community groups to enhance social connection outcomes and new understanding about the role of social infrastructure in enhancing community connection. Improved social connection is expected to improve resilience and community wellbeing.
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Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. ....Engaging ethnic minority and majority blood donors in donor recruitment. Word-of-mouth is a potentially powerful way to recruit blood donors. Talking about donation increases awareness, trust, commitment and positive feelings about donating, particularly in ethnic minority groups. However, donors seldom tell others about donating. This project aims to determine how to motivate blood donors to recruit new donors using word-of-mouth, through research comprising co-design, surveys, and experiments. This project will generate new knowledge of how to encourage effective word-of-mouth for pro-social behaviours. Expected outcomes include producing culturally relevant, validated resources that will significantly benefit Australia by encouraging effective conversations to promote blood donation in all communities.Read moreRead less
Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focu ....Belonging and sexual citizenship among gender and sexual minority youth. In the context of well-documented threats to the mental health and well-being of minority young people, this project will examine the experiences of two different generations of gender and sexual minority youth growing up in Australia, and the sources of support they have found most useful. Innovative contextual analysis will involve documentary and archival research alongside individual and group interviews. Through a focus on the promotion of well-being and participatory citizenship in a rapidly changing social world, the findings aim to contribute new theory concerning transitions from youth to adulthood, improved methodology for the study of marginal and sometimes hard-to-reach populations, and better quality policy and practice.Read moreRead less
Trade policy: maximising benefits for nutrition, food security, human health, and the economy. Depending on how it is done, trade can be good or bad for peoples' health and social well-being. This study will provide evidence to support the development of trade policy which combines economic as well as social and health goals. This will help improve global food security and human health, reduce poverty and support good international relations.
Indigenous young people's resilience and wellbeing. This project aims to identify factors related to, and those which predict, the development of resilience and wellbeing in Indigenous youth. Resilience protects the social and emotional wellbeing of youth exposed to high levels of adversity, and reduces the likelihood of substance misuse, violence, and risky behaviour. This project will examine the development of resilience and wellbeing in Indigenous youth; compare Indigenous youth’s self-asses ....Indigenous young people's resilience and wellbeing. This project aims to identify factors related to, and those which predict, the development of resilience and wellbeing in Indigenous youth. Resilience protects the social and emotional wellbeing of youth exposed to high levels of adversity, and reduces the likelihood of substance misuse, violence, and risky behaviour. This project will examine the development of resilience and wellbeing in Indigenous youth; compare Indigenous youth’s self-assessment of their resilience and wellbeing between low and high risk cohorts; and study how community services develop youth wellbeing and resilience. The expected benefit of this research is a better understanding of connections among age, cultural identity, resilience, wellbeing and risky behaviours in Indigenous youth.Read moreRead less
Governing harmful commodities: the case of ultra-processed foods. This project aims to generate new knowledge on how to influence public policy in order to reduce the supply and consumption of a health-harming commodity, ultra-processed foods. Using governance theory and qualitative techniques the project intends to identify the actors who are influential in the three key policy areas of trade, taxation and marketing and who affect the consumption of these foods in Australia, Thailand and Fiji. ....Governing harmful commodities: the case of ultra-processed foods. This project aims to generate new knowledge on how to influence public policy in order to reduce the supply and consumption of a health-harming commodity, ultra-processed foods. Using governance theory and qualitative techniques the project intends to identify the actors who are influential in the three key policy areas of trade, taxation and marketing and who affect the consumption of these foods in Australia, Thailand and Fiji. Expected outcomes include strategies for pursuing these different actors’ interests and evidence that can help institutions to promote better policies. Intended benefits include better nutrition outcomes in Australia, Thailand and Fiji.Read moreRead less
Caring at end of life: understanding the nature and effect of informal community care networks for people dying at home. This project will provide an understanding of the function and purpose of caring networks for people at the end of their life, specifically for people who are dying at home. This understanding will enable the development of communities capacity in addition to informing a national health promotion approach to palliative care.
Pharmacology Of Potential Anti-Tumour Agents: Iron Chelators Of The BpT Class
Funder
National Health and Medical Research Council
Funding Amount
$585,455.00
Summary
Pharmacology of Potential Anti-Tumour Agents: Iron Chelators of the BpT Class Cancer cells have a high iron requirement for DNA synthesis and many clinical trials showed Fe chelators are effective anti-cancer drugs. Their potential to act as anti-tumour agents has been confirmed by the entrance of Triapine into widespread NCI clinical trials. In this NHMRC Renewal, we will perform pharmacological and preclinical studies to promote the development of BpT chelators as novel anti-tumour agents.