The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the h ....Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the health system. The data collected in this project will assist in developing health services to meet these needs.Read moreRead less
Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to ....Innovation in agricultural sector Green House Gas abatement in NSW. This project aims to develop a land sector greenhouse gas abatement, food production and environmental economics model for NSW. We expect to identify innovation in carbon payment policy and brokerage business models to achieve agricultural GHG abatement, while simultaneously improving sustainability. Expected outcomes include evaluation of the innovations of expert landholders, related businesses and governments to find ways to influence land use decisions. This should provide significant benefits to landholders, governments involved in land management and the public through increased productivity, profitability, biodiversity and ecosystem health in the context of future climate, agricultural commodity and carbon market uncertainties.Read moreRead less
Do root microbiomes control seagrass response to environmental stress? The project aims to determine the role root microbes play in controlling seagrass responses to environmental stress. By integrating marine and microbial ecology, environmental genomics and ecosystem function (e.g., biogeochemical cycling), this project is significant as it will create new knowledge of the processes that confer seagrass resilience to global environmental issues. An expected outcome is an increased understandin ....Do root microbiomes control seagrass response to environmental stress? The project aims to determine the role root microbes play in controlling seagrass responses to environmental stress. By integrating marine and microbial ecology, environmental genomics and ecosystem function (e.g., biogeochemical cycling), this project is significant as it will create new knowledge of the processes that confer seagrass resilience to global environmental issues. An expected outcome is an increased understanding of how microbes control seagrass health and an enhanced capacity to develop effective restoration strategies for Australia's valuable seagrass ecosystems. Benefits include improving the extensive environmental, economic, social/cultural services Australian communities derive from seagrass ecosystems.Read moreRead less
Unusual trisulfide chemistry. This project aims to investigate the mechanism of an unexpected reaction of trisulfides with common amide-containing solvents. Specifically, these solvents (such as dimethylformamide) were discovered to cleave S-S bonds in trisulfides and related polysulfides. This project expects to generate new knowledge in the understanding of the reaction mechanism and then use that understanding for useful chemistry. Expected outcomes of this project include a mechanistic under ....Unusual trisulfide chemistry. This project aims to investigate the mechanism of an unexpected reaction of trisulfides with common amide-containing solvents. Specifically, these solvents (such as dimethylformamide) were discovered to cleave S-S bonds in trisulfides and related polysulfides. This project expects to generate new knowledge in the understanding of the reaction mechanism and then use that understanding for useful chemistry. Expected outcomes of this project include a mechanistic understanding of a new reaction, and the use of this chemistry in polymer synthesis and polymer recycling. This project should provide significant benefits in new knowledge, as well as support new strategies in polymer synthesis and recycling to benefit the environment.Read moreRead less
Beyond fire frequency: understanding fire season for ecosystem management. This project aims to investigate how the season of fire, arguably one of the biggest changes brought about by fire management, can impact ecosystems and the persistence of threatened species. The project expects to generate new yet fundamental knowledge of how the timing of fire has shifted, using a multidisciplinary team with expertise in remote sensing and fire ecology, and experimentally assess fire season effects on s ....Beyond fire frequency: understanding fire season for ecosystem management. This project aims to investigate how the season of fire, arguably one of the biggest changes brought about by fire management, can impact ecosystems and the persistence of threatened species. The project expects to generate new yet fundamental knowledge of how the timing of fire has shifted, using a multidisciplinary team with expertise in remote sensing and fire ecology, and experimentally assess fire season effects on soil properties and plant persistence. The project aims to enhance capacity of conservation agencies across Australia to effectively implement fires while maintaining biodiversity values. This should provide significant benefits for informed management of the large numbers of threatened species under their protection.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Trade and investment in the face of declining international cooperation. This project aims to investigate the impact and policy implications of trade and investment policies in a world trade system facing increasing uncertainty. The project intends to gain an improved understanding of investment regulations like Investor State Dispute Settlement (ISDS) agreements and their impact on trade and foreign direct investment. Expected outcomes include new theories for the breakdown of international agr ....Trade and investment in the face of declining international cooperation. This project aims to investigate the impact and policy implications of trade and investment policies in a world trade system facing increasing uncertainty. The project intends to gain an improved understanding of investment regulations like Investor State Dispute Settlement (ISDS) agreements and their impact on trade and foreign direct investment. Expected outcomes include new theories for the breakdown of international agreements and their effects on third world countries as well as empirical methods that allow for a quantification of the welfare and employment effects of investment policies like ISDS. This project should provide benefits by informing government policy makers to improve Australia’s trade and investment policies.Read moreRead less
Geographical Indications for Wine in Australia’s Free Trade Agreements. This project aims to clarify the appropriate basis for protecting geographical indications for wines in trade agreements and domestic legal systems. The project expects to generate new knowledge concerning the criteria, evidence and procedure that should be required to establish a geographical indication. Existing law risks misuse of this mechanism to unjustifiably protect domestic markets; the European Union is seeking prot ....Geographical Indications for Wine in Australia’s Free Trade Agreements. This project aims to clarify the appropriate basis for protecting geographical indications for wines in trade agreements and domestic legal systems. The project expects to generate new knowledge concerning the criteria, evidence and procedure that should be required to establish a geographical indication. Existing law risks misuse of this mechanism to unjustifiably protect domestic markets; the European Union is seeking protection for what appear to be grape varieties rather than geographical indications. Expected outcomes include evidence-based recommendations to government and industry. Project outcomes should benefit Australian economic interests by enhancing Australia’s ability to resist spurious geographical indication claims.Read moreRead less
Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected ....Transforming Cultural & Natural Resource Management workforce capabilities. This project aims to implement a transformative program of transdisciplinary cultural and natural resource management and workforce development research in Northern Australia’s Arnhem Plateau region. This project expects to create new knowledge in the areas of cultural knowledges, wildfire, feral animal, invasive plants, mine-site rehabilitation, and climate change, as well as Indigenous training effectiveness. Expected outcomes of the project include practical learnings for application in broader Indigenous community/First Nations capability and supportive policy development contexts. The expected benefits are a long-term platform for enhancing cultural and environmental landscape management and sustainable employment opportunities.Read moreRead less