The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the h ....Reducing health disparities for culturally and linguistically diverse peoples. This project aims to develop a greater understanding of migrants and the factors that predict poor health outcomes related to blood-borne viruses and sexually transmitted infections. The delayed access by migrants to healthcare from culturally and linguistically diverse backgrounds results in late diagnosis, low treatment uptake, and poorer health outcomes, with enhanced risk of infection and increased burden on the health system. The data collected in this project will assist in developing health services to meet these needs.Read moreRead less
Industrial Transformation Research Hubs - Grant ID: IH190100022
Funder
Australian Research Council
Funding Amount
$4,787,259.00
Summary
ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop pr ....ARC Research Hub for Sustainable Crop Protection. The Hub aims to develop and commercialise an innovative biological alternative to chemical fungicides targeting economically significant diseases of broadacre and horticultural crops. It addresses industry challenges of fungicide resistance, chemical residues in food, off-target effects and environmental harm. It builds on ground-breaking ‘BioClay’ platform to deliver pathogen targeting RNA using clay particles as non-genetically modified crop protection. An expert multidisciplinary team uniting science, commercial and social licence pathways ensures industry and consumer uptake advancing $60B Australian Agriculture. The Hub translates to increased productivity, market access and enhanced environmental credentials of Australian food.
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Trade and investment in the face of declining international cooperation. This project aims to investigate the impact and policy implications of trade and investment policies in a world trade system facing increasing uncertainty. The project intends to gain an improved understanding of investment regulations like Investor State Dispute Settlement (ISDS) agreements and their impact on trade and foreign direct investment. Expected outcomes include new theories for the breakdown of international agr ....Trade and investment in the face of declining international cooperation. This project aims to investigate the impact and policy implications of trade and investment policies in a world trade system facing increasing uncertainty. The project intends to gain an improved understanding of investment regulations like Investor State Dispute Settlement (ISDS) agreements and their impact on trade and foreign direct investment. Expected outcomes include new theories for the breakdown of international agreements and their effects on third world countries as well as empirical methods that allow for a quantification of the welfare and employment effects of investment policies like ISDS. This project should provide benefits by informing government policy makers to improve Australia’s trade and investment policies.Read moreRead less
Psyllids as biosecurity threats to plantation and native eucalypts in Australia and internationally. Psyllids are tiny cicada-like insects that are economic pests of forestry and horticulture because the saliva injected when feeding causes leaf death and some vector plant diseases. Advanced technologies and procedures will be used to determine what makes plants susceptible to psyllids and to improve Australian preparedness ahead of an incursion.
Special Research Initiatives - Grant ID: SR0354908
Funder
Australian Research Council
Funding Amount
$10,000.00
Summary
The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outco ....The Insect-Plant Chemical Ecology Network (IPCEN). We bring together plant molecular biology, entomology and analytical chemistry to transform three leading fields of Australian research into an advanced science with far reaching capabilities in innovative research and applied outcomes. Expertise studying the biochemical pathways that produce specific plant compounds and expertise in insect recognition and response to these chemicals will be brought together. This will lead to new research outcomes and solutions to problems in agriculture, horticulture, forestry and protection of Australia's native flora. Researchers are struggling to create these links, constrained by disciplinary boundaries and geographical isolation. Key industries and researchers already support this proposal.Read moreRead less
Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health ....Normative study of a checklist of emotional and behavioural disturbance in adults with intellectual disability. People with intellectual disability (ID) are three times more likely to suffer mental illness than the general community, making this a bigger problem than schizophrenia. They are a great burden to their carers and cost to the community but their mental health problems remain largely untreated. This study aims to conduct the largest and most comprehensive survey of the mental health of adults with ID that has been undertaken internationally to date. The population will cover the age span of late adolescence (16 years) through the transition to adult life then through to the elderly. The research will establish the prevalence and nature of mental illness and potential risk factors in a large representative population of adults with ID.Read moreRead less
Trust makers, breakers and brokers: building trust in the Australian food system. This research will compare and contrast the way that food trust is managed in Australia and the United Kingdom, with a particular focus on how trust is damaged and repaired. Using consensus-testing processes, best practice models will be developed to assist government, industry, media and consumer groups to build and maintain trust in the food supply.
Time scarcity in Australian families: another inequity? The globalising economy, financial uncertainties and major democratic changes are all affecting family time. Parent's time is a resource on which children depend, but time scarcity has become a widespread problem for families. Our study helps focus policy attention on this problem. We deliver new methods to assess the experience of time scarcity in families, identifying those who are most likely to experience it, where they live, and how ti ....Time scarcity in Australian families: another inequity? The globalising economy, financial uncertainties and major democratic changes are all affecting family time. Parent's time is a resource on which children depend, but time scarcity has become a widespread problem for families. Our study helps focus policy attention on this problem. We deliver new methods to assess the experience of time scarcity in families, identifying those who are most likely to experience it, where they live, and how time scarcity affects them. This evidence can help support policy approaches to time, benefiting the twin economic and social policy goals of encouraging workforce participation while supporting the health and wellbeing of families.Read moreRead less
Sexual health and relationships in young Indigenous people. Despite higher notified rates of sexually transmissible infections and blood borne viruses and often negative depictions of young indigenous people, very little is known of the health and well being of young Indigenous people. This project will for the first time provide a national profile of risk behaviours, levels of knowledge and the types of health services young Indigenous people access for sexual health and blood borne viruses. Th ....Sexual health and relationships in young Indigenous people. Despite higher notified rates of sexually transmissible infections and blood borne viruses and often negative depictions of young indigenous people, very little is known of the health and well being of young Indigenous people. This project will for the first time provide a national profile of risk behaviours, levels of knowledge and the types of health services young Indigenous people access for sexual health and blood borne viruses. The findings of this research will set the foundations for a longer term strategy to ensure trends and behaviours can be identified among the population and where necessary interventions can be implemented. Read moreRead less