The unfolding story of the 2009 Adelaide heatwave: risk factors for mortality and morbidity. This project will conduct a case control study in Adelaide to explore the risk factors of extra health burden related to the 2009 heatwave. Given the prediction of more extreme heat events, this study will provide important information for policy makers and service providers to assist in the development of more resilient communities to climate change.
Asymmetric Synthesis and Biological Evaluation of Bioactive Alkaloids and their Analogues. We propose to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodolo ....Asymmetric Synthesis and Biological Evaluation of Bioactive Alkaloids and their Analogues. We propose to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodology and products developed may have potential pharmaceutical and agricultural applications from which the country could benefit from in the future. This project would help developed skilled people that may develop innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.Read moreRead less
Stereoselective Synthesis of Bioactive Alkaloids for Structure Elucidation and Drug Discovery. It is proposed to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The m ....Stereoselective Synthesis of Bioactive Alkaloids for Structure Elucidation and Drug Discovery. It is proposed to develop innovative methods for preparing bioactive natural products and their analogues with potential applications as new and safer therapeutic drugs and agricultural chemicals. This project would make important scientific contributions to the advancement of the fundamentals of synthetic organic chemistry and contribute to Australia's development as a knowledge-based economy. The methodology and products developed are likely to have potential pharmaceutical and agricultural applications from which the country could benefit in the future. This project will train skilled people who may develop innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.Read moreRead less
Large Scale Production of Stemona Alkaloids for Agricultural Applications and New Drug Discovery. The Stemona alkaloids form a large group of natural products that have significant potential as agricultural and pharmaceutical drugs. Extracts of these natural products have many applications in traditional medicine and as insecticides in Asia. We propose to develop innovative methods for the large scale production and synthesis of these bioactive alkaloids. The methodology and products developed ....Large Scale Production of Stemona Alkaloids for Agricultural Applications and New Drug Discovery. The Stemona alkaloids form a large group of natural products that have significant potential as agricultural and pharmaceutical drugs. Extracts of these natural products have many applications in traditional medicine and as insecticides in Asia. We propose to develop innovative methods for the large scale production and synthesis of these bioactive alkaloids. The methodology and products developed may have potential pharmaceutical and agricultural applications from which the country could benefit in the future. This project would help develop skilled people who may produce innovative outcomes in the future, especially in the developing pharmaceutical and biotechnology industries in Australia.Read moreRead less
Caring for the carers: occupational health and safety in homecare. Homecare workers care for vulnerable clients but their own vulnerability to health and safety risks is seldom examined. Pilot research revealed unrecognised hazards arising from the isolated and fragmented nature of the work. This project will systematically identify hazards and develop interventions to promote healthier and safer homecare work.
The NSW child development study. Research shows that a child's development predicts health and social outcomes later in life. This Australian project will be the first to identify risk and protective factors associated with these outcomes in 87,000 children from birth to 10 years. The results will help inform governments to improve our children's health and educational achievements.
Time scarcity in Australian families: another inequity? The globalising economy, financial uncertainties and major democratic changes are all affecting family time. Parent's time is a resource on which children depend, but time scarcity has become a widespread problem for families. Our study helps focus policy attention on this problem. We deliver new methods to assess the experience of time scarcity in families, identifying those who are most likely to experience it, where they live, and how ti ....Time scarcity in Australian families: another inequity? The globalising economy, financial uncertainties and major democratic changes are all affecting family time. Parent's time is a resource on which children depend, but time scarcity has become a widespread problem for families. Our study helps focus policy attention on this problem. We deliver new methods to assess the experience of time scarcity in families, identifying those who are most likely to experience it, where they live, and how time scarcity affects them. This evidence can help support policy approaches to time, benefiting the twin economic and social policy goals of encouraging workforce participation while supporting the health and wellbeing of families.Read moreRead less
Sexual health and relationships in young Indigenous people. Despite higher notified rates of sexually transmissible infections and blood borne viruses and often negative depictions of young indigenous people, very little is known of the health and well being of young Indigenous people. This project will for the first time provide a national profile of risk behaviours, levels of knowledge and the types of health services young Indigenous people access for sexual health and blood borne viruses. Th ....Sexual health and relationships in young Indigenous people. Despite higher notified rates of sexually transmissible infections and blood borne viruses and often negative depictions of young indigenous people, very little is known of the health and well being of young Indigenous people. This project will for the first time provide a national profile of risk behaviours, levels of knowledge and the types of health services young Indigenous people access for sexual health and blood borne viruses. The findings of this research will set the foundations for a longer term strategy to ensure trends and behaviours can be identified among the population and where necessary interventions can be implemented. Read moreRead less
Public and ethical responses to mandated alcohol warning labels about increased long-term risk of cancer. This project will determine how the Australian public will respond to the proposed introduction of alcohol product warning labels. It will establish how such at point of sale messages can acceptably and effectively inform Australians about the long-term, but modifiable, cancer risk associated with alcohol use and reduce the national cancer burden.
Bushfires, social connectedness and mental health. The 2009 Victorian bushfires caused much loss of life, property destruction, and community disturbance. It is important for Promoting Better Health and Strengthening the Social and Economic Fabric that an accurate understanding is achieved of the factors that contribute to optimal recovery from natural disasters. This project will survey people affected by the fires over 5 years to both profile adaptation after the fires and to identify the i ....Bushfires, social connectedness and mental health. The 2009 Victorian bushfires caused much loss of life, property destruction, and community disturbance. It is important for Promoting Better Health and Strengthening the Social and Economic Fabric that an accurate understanding is achieved of the factors that contribute to optimal recovery from natural disasters. This project will survey people affected by the fires over 5 years to both profile adaptation after the fires and to identify the individual and community processes that influence outcome. This project being undertaken in partnership by academic, disaster management, health and community organisations will provide crucial information for shaping policy for disaster management in the years ahead.Read moreRead less