Women's Hormones And Health Across The Adult Life Span
Funder
National Health and Medical Research Council
Funding Amount
$951,005.00
Summary
Sex hormones are important in younger and older women’s health. However, normal levels of sex hormones for women of different ages and the extent to which sex hormones are associated with common health outcomes are yet to be established. These issues will be systematically studied in comprehensive, community-based studies of younger and older Australian women. The findings will be immediately translated into clinical practice guidelines and community education.
Addressing Evidence-practice Gaps In Chronic Disease Prevention And Control
Funder
National Health and Medical Research Council
Funding Amount
$709,931.00
Summary
Cardiovascular diseases are the leading causes of premature death and disability worldwide. Effective treatments for prevention and control of these conditions are available however their use remains far from optimal, in Australia and globally. My current and proposed research will develop and evaluate highly innovative solutions to reduce large evidence-practice gaps in healthcare delivery. These include task shifting to non-physician health workers and novel approaches to drug delivery.
Large Scale Data For Common, Potentially Modifiable Causes Of Morbidity And Mortality
Funder
National Health and Medical Research Council
Funding Amount
$761,656.00
Summary
Large-scale cohort studies, that follow the health of a large proportion of the general population over time, have enormous potential to inform disease prevention and the optimal use of health services. The planned research will use large scale cohort study data, linked to data on health outcomes and use of health services to provide much needed evidence on Indigenous health, safety of medicines and healthy ageing.
Improving Health Outcomes With Ageing And Diabetes: A Focus On Prevention And Management Of Cardiovascular Disease
Funder
National Health and Medical Research Council
Funding Amount
$638,517.00
Summary
My research combines interventional trials, epidemiology and health services implementation research with a focus on prevention of cardiovascular disease, disability and dementia, including in the elderly and those with diabetes. With direct impact on the routine care of people who succumb to disabling vascular complications, it will evaluate treatment strategies but also influence change in health care and policy through the provision of trial evidence and evidence-based health services.
Promoting Healthy Ageing Of Brain And Mind Through Epidemiology And Intervention Research
Funder
National Health and Medical Research Council
Funding Amount
$664,584.00
Summary
This project focuses on identifying ways that individuals and societies can promote healthy ageing to prevent dementia and mental health problems in later life. Large-scale longitudinal studies and intervention studies will be evaluated to identify factors that lead to healthy and unhealthy ageing.
Social And System Determinants Of Indigenous Health: Closing The Gap In Outcomes For Indigenous Australians With Cancer
Funder
National Health and Medical Research Council
Funding Amount
$639,183.00
Summary
This Fellowship will support one of Australia’s foremost leaders in the field of the Indigenous health research to undertake a major research program aimed at reducing inequity in health and health care. The main focus over the next five years will be on understanding and improving services for Aboriginal and Torres Strait Islander people with cancer, in order to reduce the marked disparities in diagnosis, treatment and survival for Indigenous Australians.
Personalised Genomics In Precision Medicine Of Psychotic Illness
Funder
National Health and Medical Research Council
Funding Amount
$631,370.00
Summary
This research program will utilise recent developments in genomic technology to make detailed high-resolution genetic maps of individuals with psychotic illness. Where conventional gene discovery approaches focus on differences at the population level this program will integrate the variation within individuals to determine the network architecture. This will be used to generate genetic profiles for personalised medicine and provide the basis for treatments that are tailored to individuals.
Psychiatric disorders are associated with considerable social and economic burden which could be reduced if we understood mental health outcomes in high risk populations. This fellowship will use advanced brain imaging to understand the development of mental health disorders in those at high risk of bipolar disorder and dementia.
This fellowship support will allow A/Prof Xiao-Jun DU to pursue his recent pre-clinical research findings on novel therapeutic interventions for cardiovascular diseases. He will particularly focus on new treatment of accumulation of excessive scar tissues (fibrosis) in the heart and large arteries following disease and cardiac inflammation, factors knowing to play pivotal roles in progression of cardiovascular diseases.
I am an aged care rehabilitation researcher seeking to minimise disability and prevent falls in large numbers of older people. I am particularly interested in the role of exercise in falls and disability prevention.