A Parent Education And Skills Training Intervention For Young Adolescents With Autism
Funder
National Health and Medical Research Council
Funding Amount
$436,500.00
Summary
Autism is a most severe and prevalent lifelong developmental disorder affecting approximately one in every thousand children and their families. Autism is associated with personal suffering and is a significant burden and stress for parents, families and carers and cost to the community. In earlier work we have demonstrated that providing a structured program of parent education and guidance to families with preschool children with autism leads to improved parental adjustment and mental health. ....Autism is a most severe and prevalent lifelong developmental disorder affecting approximately one in every thousand children and their families. Autism is associated with personal suffering and is a significant burden and stress for parents, families and carers and cost to the community. In earlier work we have demonstrated that providing a structured program of parent education and guidance to families with preschool children with autism leads to improved parental adjustment and mental health. The program also led to behavioural and developmental benefits for the child. The early secondary school years bring further stress and difficulty to adolescents with autism and their families. This project aims to assess the effectiveness of a parent education and training program for parents with autistic adolescents aged 12-14 years. If shown to be effective, this manual based intervention can be readily used by professionals to promote parent mental health, family adjustment and improve the wellbeing and outcome for adolescents with autism. As a result, family stress and the necessity of out of home care may be reduced and school participation improved.Read moreRead less
Azithromycin Versus Placebo In The Treatment Of Asymptomatic Acute Otitis Media In Young Aboriginal Children : A RCT
Funder
National Health and Medical Research Council
Funding Amount
$1,357,460.00
Summary
Remote Aboriginal children have the highest rates of severe ear infection reported in the medical literature. At any time, large numbers of children have a bulging eardrum (acute otitis media) but most are completely asymptomatic. In our previous antibiotic study, acute otitis media (AOM) persisted in 50% of children after 1 week of treatment. In terms of clinical success, it didn't make any difference whether azithromycin or amoxicillin was used (although azithromycin seemed to be better at red ....Remote Aboriginal children have the highest rates of severe ear infection reported in the medical literature. At any time, large numbers of children have a bulging eardrum (acute otitis media) but most are completely asymptomatic. In our previous antibiotic study, acute otitis media (AOM) persisted in 50% of children after 1 week of treatment. In terms of clinical success, it didn't make any difference whether azithromycin or amoxicillin was used (although azithromycin seemed to be better at reducing the level of infection). Currently local clinicians are: i) uncertain whether antibiotics make any difference at all; and ii) reluctant to devote resources to case-finding without good evidence of substantial benefit. In this randomised controlled trial, we will determine the benefits of 2 doses of azithromycin given 1 week apart in children with asymptomatic acute otitis media will improve health outcomes. The results of the trial will become the best available evidence to guide the medical management of asymptomatic AOM in high-risk children. We anticipate that it will make an important contribution in the shift toward more effective prevention and management of otitis media in Australian Aboriginal children. It will also have implications for all disadvantaged populations where adverse outcomes are common and compliance with recommended treatment is poor.Read moreRead less
Laser Acupuncture In Patients With Chronic Knee Pain: A Randomised Placebo-controlled Trial
Funder
National Health and Medical Research Council
Funding Amount
$701,120.00
Summary
Chronic knee pain is a common and disabling musculoskeletal condition that causes a loss of functional independence and results in significant health care costs. In the majority of patients the most common cause is osteoarthritis. Acupuncture is a form of non-surgical treatment commonly sought by patients and often recommended by GP's. The main outcomes from our project are to establish the role, clinical effectiveness and cost benefit of laser and needle acupuncture in knee pain patients.
Can Self-management Education Programs Improve Outcomes Of People With Osteoarthritis?
Funder
National Health and Medical Research Council
Funding Amount
$343,874.00
Summary
Arthritis is a very common disease associated with pain, disability and poor quality of life. An important way that people with arthritis can deal with the disease is through using a variety of self-management behaviours and coping strategies as well as becoming well informed about the best available treatments. A specific course was developed in he US to help people self-manage. It has been available in Australia for 20 years through Arthritis Foundations and has become their core business. Tre ....Arthritis is a very common disease associated with pain, disability and poor quality of life. An important way that people with arthritis can deal with the disease is through using a variety of self-management behaviours and coping strategies as well as becoming well informed about the best available treatments. A specific course was developed in he US to help people self-manage. It has been available in Australia for 20 years through Arthritis Foundations and has become their core business. Treatment guidelines used by doctors to treat people with arthritis regularly recommend that patients should be referred to such courses. Although the course is widely distributed, the evidence scientific evidence regarding its effectiveness is patchy, and some overviews suggest it is not useful at all. Confusion exists regarding the value of the course. While treatment guidelines advise doctors to refer patients to the program by very few GPs, Rheumatologist or Orthopaedic surgeons do refer. The proposed study is a large controlled trial which will provide essential evidence to inform patients, doctors and policy makers on the benefits of the course. It will involve people with well defined moderate to severe arthritis who have consulted a surgeon or rheumatologist. People will be randomised to receive the intervention (two hours per week, six session course including an 'arthritis self-help' book) will be compared with people in a control group (who only receive the book without instruction). People will be followed for 1 year to see if the course improves quality of life, health behaviours, and whether less health care resources (ie attendance at doctors or less medication use) are used. The results of this study will be influential in determining government policy as the number of people with chronic diseases like arthritis is rapidly growing and the acute healthcare system, including hospitals, are poorly equipped to deal with this growing problem.Read moreRead less
Effect Of Naltrexone Treatment On Mental Health And Other Health Outcomes : A Record Linkage Study.
Funder
National Health and Medical Research Council
Funding Amount
$111,625.00
Summary
Research has shown that heroin use is an increasing habit of Australia's youth with morbidity and mortality rates for regular heroin users significantly greater than that for the general population. Despite the introduction of a number of treatment options to combat the problem, the management of dependent heroin use has proved problematic. This application addresses an issue of considerable importance and controversy in recent years, namely, the impact of naltrexone and methadone treatment on m ....Research has shown that heroin use is an increasing habit of Australia's youth with morbidity and mortality rates for regular heroin users significantly greater than that for the general population. Despite the introduction of a number of treatment options to combat the problem, the management of dependent heroin use has proved problematic. This application addresses an issue of considerable importance and controversy in recent years, namely, the impact of naltrexone and methadone treatment on morbidity and mortality among persons who are heroin dependent. The study will be carried out using a unique system of linked hospital records from the Western Australian Health Services Research Linkage Unit at the Department of Health Western Australia (DHWA). Through this system hospital, mental health and death records derived from different sources, but related to the same individual are electronically linked. Hence, record linkage provides an independent method for obtaining information on treatment outcomes which is free from subjective bias. In the current study records from heroin users who entered naltrexone maintenance and a smaller group who entered methadone maintenance will be linked to the DHWA database. Collectively these data will be used to quantify morbidity, hospital episodes, mental health issues and mortality in heroin users following commencement of naltrexone maintenance treatment. Data will also be used to compare positive and negative outcomes for individuals on naltrexone with those on methadone. The results will be used to advocate on behalf of this vulnerable population in a country that prides itself on universal access to high quality health services. It is anticipated that this study will have a substantial beneficial impact on the management of illicit drug use policy and as well as contributing new research methods, findings and international knowledge.Read moreRead less
Oestrogens And The Metabolic Process: Regulatory Interaction With The GH-IGF-system In Health And Disease
Funder
National Health and Medical Research Council
Funding Amount
$547,970.00
Summary
Growth hormone (GH) plays a key role in controlling body metabolism, fat and muscle in adult life. The female hormone oestrogen controls how much GH is secreted and how well it acts. Drugs that act like or interfere with the action of oestrogen are used increasing for the treatment of many conditions e.g. growth, cancer and osteoporosis. This proposal examines their impact on cardiovascular and physical health.