Discovery Early Career Researcher Award - Grant ID: DE130100894
Funder
Australian Research Council
Funding Amount
$361,140.00
Summary
Nanolamps: unlocking targeted gene silencing in deep tissue with nanoparticle-based light sources. In order to better understand the function of genes, this project will develop a new method of tightly targeted gene silencing deep inside of the body by nanoscale light sources. This will shed new light on the nervous system and, in the first instance, help to elucidate the role of the PACAP neurons in blood pressure regulation.
The changing landscapes of medical pluralism: a sociological analysis of patient experiences and decision making in Australia, India and Brazil. This project examines the respective roles of biomedicine and traditional, complementary and alternative medicine in supporting health needs in Australia, Brazil and India. It will be the first sociological study to compare how different countries balance biomedical approaches to health with more alternative approaches.
Beyond successful ageing: Longevity & healthy ageing among Australian women. This project has three key aims. First, to test and contrast two empirical models of successful ageing. Secondly, to compare these empirical models with women’s own perspectives of their ageing gained from prospective qualitative data. Thirdly, provide insights into women’s experience of very old age through interviews with women in their 90s. In addition to interview data, the project will analyse data from the 1921-2 ....Beyond successful ageing: Longevity & healthy ageing among Australian women. This project has three key aims. First, to test and contrast two empirical models of successful ageing. Secondly, to compare these empirical models with women’s own perspectives of their ageing gained from prospective qualitative data. Thirdly, provide insights into women’s experience of very old age through interviews with women in their 90s. In addition to interview data, the project will analyse data from the 1921-26 and 1946-51 cohorts of the Australian longitudinal study on women’s health. The expected outcomes will provide significant benefits, such as projecting potential health trajectories as women enter their later years.Read moreRead less
Addressing race-based discrimination in Australia: a cost-benefit analysis. This project is designed to produce sustainable benefits to Australian society through the provision of important data needed to promote investment in strategies to address race-based discrimination. This will benefit both the lives of individuals experiencing race-based discrimination, including those from Indigenous and culturally and linguistically diverse backgrounds. It will also benefit society as a whole through p ....Addressing race-based discrimination in Australia: a cost-benefit analysis. This project is designed to produce sustainable benefits to Australian society through the provision of important data needed to promote investment in strategies to address race-based discrimination. This will benefit both the lives of individuals experiencing race-based discrimination, including those from Indigenous and culturally and linguistically diverse backgrounds. It will also benefit society as a whole through promotion of social cohesion and community connectedness and the economic benefits resulting from increased productivity and workforce participation and reduced burden on health, social and welfare systems.Read moreRead less
Effective clinical handover communication: improving patient safety, experiences and outcomes. Communication in clinical handover (transfer of responsibility for patient care) plays a causal role in many adverse events. This project will contribute new knowledge for improvements in handover communication which will be shared across hospitals and health departments nationally to improve patient safety and reduce healthcare costs.
Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforceme ....Criminal justice outcomes of injecting drug use and methamphetamine smoking. Injection drug use (IDU) and methamphetamine smoking are associated with the majority of illicit drug-related harms and associated costs in Australia. We will extend our studies of people who inject drugs and people who smoke methamphetamine through record linkage to social and criminal justice datasets. We will characterise the trajectories of participants through social services (e.g. public housing) and law enforcement systems to provide a comprehensive account of social and criminal justice impacts of injection drug use and methamphetamine use in Australia for the first time. Read moreRead less
Development of an orally delivered genital herpes vaccine: targeting the reproductive tract using Liporale, a novel lipid-based adjuvant. This project will evaluate the potential of a novel lipid-based adjuvant platform, LiporaleTM, to induce protection against a model sexually transmitted infection, genital herpes, using an orally delivered vaccination approach. Currently 16 per cent of the world's population has been exposed to herpes and there is currently no effective vaccine available.
A critical public health examination of complementary self-medication in later life in indigenous, non-indigenous and CALD communities. This project aims to provide the first in-depth coordinated critical public health examination of an unregulated and 'covert' area of health and treatment seeking behaviour - complementary self-medication (CAM SM) use in later life. It will focus on healthy ageing and living with chronic illness and draw upon fieldwork with Indigenous, non-Indigenous and cultura ....A critical public health examination of complementary self-medication in later life in indigenous, non-indigenous and CALD communities. This project aims to provide the first in-depth coordinated critical public health examination of an unregulated and 'covert' area of health and treatment seeking behaviour - complementary self-medication (CAM SM) use in later life. It will focus on healthy ageing and living with chronic illness and draw upon fieldwork with Indigenous, non-Indigenous and culturally and linguistically diverse (CALD) communities. This project aims to identify the challenges of, and possibilities for, 'covert' CAM SM use in later life. It will provide an evidence-base to inform safe, effective care and policy for older Australians and generate novel analyses to provide significant advances and new directions for public health scholarship with regards to chronic illness and community health in later life.Read moreRead less
Effective communication and improved patient safety: Addressing the complexities of managing high risk medications in metropolitan and regional hospitals. Current costs of hospital-related incidents are around AU$2 billion per year, and the most common cause of these incidents is ineffective communication. Medication incidents relating to use of high risk medications are particularly critical because of the increased severity of patient outcomes. High risk medications are administered in busy en ....Effective communication and improved patient safety: Addressing the complexities of managing high risk medications in metropolitan and regional hospitals. Current costs of hospital-related incidents are around AU$2 billion per year, and the most common cause of these incidents is ineffective communication. Medication incidents relating to use of high risk medications are particularly critical because of the increased severity of patient outcomes. High risk medications are administered in busy environments, and involve patients who are cared for by many different health professionals in technologically complex settings. These factors increase the likelihood of more medication incidents. The unique knowledge obtained will inform policies and identify strategies for better communication. Health professionals and patients can adopt these strategies to improve medication safety.Read moreRead less
Legal and Ethical Preparedness for Pandemic Influenza. Over 40 million people in the world died in the 1918 Influenza pandemic. Any repetition could have devastating social and economic costs for Australia and the Region. Community confidence in quarantine or other restrictions in the medical management of pandemics depends on balancing protection of public health against the rights of citizens to go about their work and daily lives. By studying the adequacy of existing human pandemic influenz ....Legal and Ethical Preparedness for Pandemic Influenza. Over 40 million people in the world died in the 1918 Influenza pandemic. Any repetition could have devastating social and economic costs for Australia and the Region. Community confidence in quarantine or other restrictions in the medical management of pandemics depends on balancing protection of public health against the rights of citizens to go about their work and daily lives. By studying the adequacy of existing human pandemic influenza planning in Australia and the Asian region, this project will contribute to law reform and policy development needed to command community confidence in the ethical and public policy balances embodied in national pandemic plans, and the laws and practices which support them.Read moreRead less