FluMum: A Prospective Cohort Study Of Mother-infant Pairs Assessing The Effectiveness Of Maternal Influenza Vaccination In Prevention Of Influenza In Early Infancy
Funder
National Health and Medical Research Council
Funding Amount
$2,598,377.00
Summary
Influenza is a serious illness for young babies. Currently there are no vaccines that can be given to babies under 6 months of age to protect them from infection. This study aims to determine whether influenza vaccine given in pregnancy can prevent infection in babies up to 6 months of age.
Defensive behaviours elicited by predator odours. Rats display a powerful anxiety responses when confronted with the odours of predators such as cats. This response may occur even though rats have never encountered an actual predator before. This project aims to investigate the nature of this anxiety and the nature of the stimuli that produce it. The outcomes should be a better understanding of the neural basis and pharmacology of anxiety states and the identification of novel chemicals that hav ....Defensive behaviours elicited by predator odours. Rats display a powerful anxiety responses when confronted with the odours of predators such as cats. This response may occur even though rats have never encountered an actual predator before. This project aims to investigate the nature of this anxiety and the nature of the stimuli that produce it. The outcomes should be a better understanding of the neural basis and pharmacology of anxiety states and the identification of novel chemicals that have powerful rodent repellent properties. Such chemicals may be of great use in domestic and agricultural contexts where rodents are pests.Read moreRead less
OptiMalVax: Optimizing A Deployable High Efficacy Malaria Vaccine
Funder
National Health and Medical Research Council
Funding Amount
$494,618.00
Summary
In this proposal, a consortium comprising many of the leading malariologists, vaccine researchers and product developers in Europe, USA, Australia and Africa will collaborate in an exciting programme of antigen discovery science linked to rapid clinical development of new vaccine candidates against malaria.
How we remember and misremember traumatic experiences. The project addresses a significant and important problem: the role of memory distortion in Post Traumatic Stress Disorder (PTSD), a global disorder with significant personal, societal and economic costs. The aim of this project is to empirically investigate the extent, causes and triggering conditions of errors in memory for traumatic experiences; particularly exaggeration of these memories, which has been linked to poor psychological adjus ....How we remember and misremember traumatic experiences. The project addresses a significant and important problem: the role of memory distortion in Post Traumatic Stress Disorder (PTSD), a global disorder with significant personal, societal and economic costs. The aim of this project is to empirically investigate the extent, causes and triggering conditions of errors in memory for traumatic experiences; particularly exaggeration of these memories, which has been linked to poor psychological adjustment. Understanding how people exposed to trauma remember, and misremember, aspects of their experiences in ways that influence their recovery is both theoretically and practically important. Indeed, it will help us refine theory and identify possible points of intervention for PTSD sufferers.Read moreRead less
Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The proj ....Microeconomic effects of Australian natural disasters. This project aims to describe and identify the effects of Australian natural disasters – such as the Black Saturday bushfires and the Brisbane floods – on important microeconomic outcomes, including health, education and employment. Natural disasters have profound economic and social effects on individuals and communities. This project intends to bring evidence on how disasters affect individuals and how the effects can be lessened. The project expects to inform policy-makers on these critical issues by analysing field, survey and administrative data on individuals before and after past disasters.Read moreRead less
Nanosilver antimicrobial resistance in target pathogens. This project aims to elucidate the important phenomena of bacterial resistance to antimicrobial nanosilver, currently one of the most developed and commercialised products of nanotechnology. The integrated research approach comprises of concurrent identification of the origins and routes of nanosilver toxicity in bacteria and the arising emergence and mechanisms of bacterial defence to the toxicity. The generated knowledge is to form a bas ....Nanosilver antimicrobial resistance in target pathogens. This project aims to elucidate the important phenomena of bacterial resistance to antimicrobial nanosilver, currently one of the most developed and commercialised products of nanotechnology. The integrated research approach comprises of concurrent identification of the origins and routes of nanosilver toxicity in bacteria and the arising emergence and mechanisms of bacterial defence to the toxicity. The generated knowledge is to form a base template for novel nanosilver engineering with less tendency for resistance development and to facilitate tracking of resistance and its spread amongst microorganisms. The knowledge has far-reaching implications on the better governance of nanosilver use, including its disposal.Read moreRead less
The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling f ....The Molecular Basis of Nanoparticle Resistance in Mixed-Species Biofilm. The project aims to understand how the globally significant mixed-species growth of pathogens develop resistance to silver nanoparticle, currently one of the most important alternative antimicrobials to antibiotics. The integrated research is to elucidate, for the first time, the nanoparticle multi-targeting toxicity on mixed-species bacterial community and how, in turn, the bacteria activate their cell-to-cell signalling for a synergistic defence to adapt to the nanoparticle toxicity. The pioneering knowledge is the foundation for technologies targeting the interspecies metabolite cross-talking to overcome the resistance phenomena, ensuring a long-term efficacy of the alternative antimicrobial on the difficult-to-control pathogenic growth.Read moreRead less
Discovery Early Career Researcher Award - Grant ID: DE190100158
Funder
Australian Research Council
Funding Amount
$405,751.00
Summary
Addressing vaccine rejection: drivers and impact of mandatory vaccination. This project aims to investigate and analyse the introduction, design and implementation of mandatory child vaccination programs in Italy, France, Australia and California, using a comparative case study approach. Parental rejection of childhood vaccines can cause illness and death. However, governments limiting personal liberty can erode public acceptance. The project’s goal is to provide the tools, framework and concept ....Addressing vaccine rejection: drivers and impact of mandatory vaccination. This project aims to investigate and analyse the introduction, design and implementation of mandatory child vaccination programs in Italy, France, Australia and California, using a comparative case study approach. Parental rejection of childhood vaccines can cause illness and death. However, governments limiting personal liberty can erode public acceptance. The project’s goal is to provide the tools, framework and conceptual clarity to help researchers and policymakers consider the merits and limitations of strategies which mandate childhood vaccination.Read moreRead less