Burden Of Disease&cost Effectiveness Of Intervention Options:informing Policy Choices & Health System Reform In Thailand
Funder
National Health and Medical Research Council
Funding Amount
$787,978.00
Summary
This research project aims to improve the scientific basis for health services provision in Thailand by filling important gaps in knowledge about the causes of disease and the possibility of effectively intervening to reduce them. Since the accuracy of the routine death registration system in Thailand is unknown, it cannot be confidently used to guide policy. The team will evaluate how accurately causes of death are being recorded, both in urban and rural areas. It will also calculate how much d ....This research project aims to improve the scientific basis for health services provision in Thailand by filling important gaps in knowledge about the causes of disease and the possibility of effectively intervening to reduce them. Since the accuracy of the routine death registration system in Thailand is unknown, it cannot be confidently used to guide policy. The team will evaluate how accurately causes of death are being recorded, both in urban and rural areas. It will also calculate how much disease and injury in Thailand is being caused by major risk factors, such as tobacco and unsafe sex. Using this information the team will evaluate the effectiveness of the major interventions to reduces diseases and injuries from risk factors that are affordable and applicable in the Thai context.Read moreRead less
Inter-relationships Between Life-stage Transitions, Depression And Cardio-metabolic Health In Young Adults
Funder
National Health and Medical Research Council
Funding Amount
$360,325.00
Summary
This study will investigate how social transitions and depression in young Australian adults affect the development of obesity and the adoption or persistence of behaviours that are associated with the risk of heart disease and diabetes. These behaviours include smoking, poor diet, physical inactivity and alcohol consumption. A better understanding of how psychosocial factors influence risk factors for heart disease and diabetes is needed to improve prevention strategies.
Follow-up Study Of Indigenous Adults In North Queensland: Chronic Diseases And Sexual Health
Funder
National Health and Medical Research Council
Funding Amount
$1,493,700.00
Summary
This study aims to follow up a cohort of Indigenous adults in rural and remote north Queensland communities who participated in the Well Persons Health Check (funded by OATSIH) during 1998-2000. Out of the 2,862 Indigenous participants, 2,503 (87.5%) agreed to have another Check in a few years time. A follow-up study is proposed for the consenting WPHC participants (any any other adults who wish to participate). This study will have 5 main objectives: 1. Estimate the incidence rate of chronic di ....This study aims to follow up a cohort of Indigenous adults in rural and remote north Queensland communities who participated in the Well Persons Health Check (funded by OATSIH) during 1998-2000. Out of the 2,862 Indigenous participants, 2,503 (87.5%) agreed to have another Check in a few years time. A follow-up study is proposed for the consenting WPHC participants (any any other adults who wish to participate). This study will have 5 main objectives: 1. Estimate the incidence rate of chronic disease conditions (diabetes, renal disease, CVD) and the main determinants of these in the north Queensland cohort (It is expected that Torres Strait Islanders will have different patterns to Aborigines), 2. Estimate the change over a 5 year period in risk factors and complications (including hospitalisations) of those with existing chronic conditions 3. At a community level, evaluate the effectiveness of local interventions aimed at health improvement (e.g. one community has drastically changed rules about alcohol availability, other communities have significantly improved the supply of fresh fruit and vegetables, still others have commenced family savings programs which improve the availability of money over the week and enable savings to buy fridges etc). 4. Estimate whether the early detection of chlamydia and gonorrhoea (using routine urine PCR testing) has lowered the community prevalence of bacterial STIs, and 5. Evaluate the effectiveness of local health promotion programs (e.g. tobacco control initiatives, healthy weight programs). The study will be undertaken in collaboration with Apunipima Cape York Health Council, the Torres Strait Health Council and relevant local community organisations. It will involve skills development for local Indigenous researchers and practitioners. Results will be given back to communities and individuals, with opportunities for further planning.Read moreRead less
Thai Health-risk Transition: A National Cohort Study
Funder
National Health and Medical Research Council
Funding Amount
$1,231,214.00
Summary
Thailand's disease patterns are changing. Some changes are good but others, like emerging diabetes, heart disease and injuries, are of concern. Development-related 'health transition' can be optimised if there is information on new causes of disease - immediate risk factors, and 'upstream' economic, cultural and environmental influences. The team will study this health-risk transition in the whole Thai population - looking back 50 years, then forwards in 100,000 Sukothai Thammathirat Open Univer ....Thailand's disease patterns are changing. Some changes are good but others, like emerging diabetes, heart disease and injuries, are of concern. Development-related 'health transition' can be optimised if there is information on new causes of disease - immediate risk factors, and 'upstream' economic, cultural and environmental influences. The team will study this health-risk transition in the whole Thai population - looking back 50 years, then forwards in 100,000 Sukothai Thammathirat Open University students living all over Thailand and followed for four years. The team will map changing risks and upstream influences, produce information for Thai preventive programs, boost regional research capacity, create a regional partnership, and support PhD and postdoctoral training.Read moreRead less
Risk And Prognostic Factors For Breast Cancer Of Different Immunohistochemical Subtypes
Funder
National Health and Medical Research Council
Funding Amount
$294,461.00
Summary
Breast cancer is a heterogeneous disease. Gene expression analysis has identified a number of subtypes that are different with respect to pathology, prognosis, and response to treatment. Building on an existing cohort study, we aim to identify risk and prognostic factors for molecular subtypes of breast cancer.
Familial, Behavioural And Environmental Determinants Of Respiratory And Metabolic Fitness In Regional South Australia.
Funder
National Health and Medical Research Council
Funding Amount
$287,321.00
Summary
South Australia is the fattest state in Australia. Limited health surveillance data suggests that Whyalla is fatter, less active, consumes more alcohol and has worse respiratory health than Adelaide. Obesity is linked to poorer respiratory health. Public concern over the effects of air pollution on the health of Whyalla families has prompted us to examine respiratory and metabolic health in Whyalla families in comparison to those in the north-west suburbs of Adelaide.
Cardiac Effects Of Exposure To Melbourne Air Pollution Caused By The 2006/2007 Bushfires In Victoria
Funder
National Health and Medical Research Council
Funding Amount
$59,000.00
Summary
This project investigates whether the air pollution that was caused by the 2006-2007 Victorian bushfires, had an effect on the health of people living in Melbourne. Cardiovascular effects will be studied by looking at hospital admissions, out-of-hospital heart attacks and the associated death toll. As it is the expectation that bushfires will increase in the future it is important to determine the impact this may have. This research will inform appropriate public health strategies.
Contextual Influences On Children's And Adolescent's Physical Activity
Funder
National Health and Medical Research Council
Funding Amount
$440,950.00
Summary
Physical inactivity has been linked to several chronic health conditions among children and adolescents. However, there has been no research that has examined the long-term physical activity habits of Australian children and how these habits change as children move into adolescence. In addition, there is only limited information regarding the factors that influence children's physical activity. This study aims to examine changes in physical activity and sedentary behaviours, such as television v ....Physical inactivity has been linked to several chronic health conditions among children and adolescents. However, there has been no research that has examined the long-term physical activity habits of Australian children and how these habits change as children move into adolescence. In addition, there is only limited information regarding the factors that influence children's physical activity. This study aims to examine changes in physical activity and sedentary behaviours, such as television viewing and computer use, that occur over three years, and also over five years, among children aged 5-6 years and 10-12 years in 2001 (baseline). As such, this study will provide information about children's physical activity habits through primary school and from late primary school to the end of secondary school. The study will also examine the influence of the family and neighbourhood environment on changes that occur in physical activity and sedentary behaviour over that time. This study is significant because it will provide information on the critical transition period between primary and secondary school. The study will identify when changes in these health behaviours occur, the extent of these changes, and the influence of factors in the family environment and the local neighbourhood on changes in these behaviours. Such information is vital to inform the development of strategies to promote and maintain health-enhancing physical activity levels and reduce sedentariness among children.Read moreRead less
Assessing Cardiovascular Disease (CVD) Risk In Aboriginal People
Funder
National Health and Medical Research Council
Funding Amount
$73,550.00
Summary
Aboriginal Australians have higher death rates from cardiovascular disease (CVD) than other Australians, with rates in young and middle aged people increased 15-fold or more. A multi-factor approach, which considers all the risk factors, is the best strategy to identify and reduce CVD risk. The first step for selection of risk-reduction therapy in an individual is to assess his-her risk status and the benefit of intervention. Several risk assessment tools, incorporating traditional risk factors, ....Aboriginal Australians have higher death rates from cardiovascular disease (CVD) than other Australians, with rates in young and middle aged people increased 15-fold or more. A multi-factor approach, which considers all the risk factors, is the best strategy to identify and reduce CVD risk. The first step for selection of risk-reduction therapy in an individual is to assess his-her risk status and the benefit of intervention. Several risk assessment tools, incorporating traditional risk factors, have been developed from Western populations. They would be most appropriately applied to individuals who resemble the study sample; their validity in Aboriginal Australians has not been evaluated and no risk prediction formulae have been developed specifically for Aboriginal people. Recent reports suggest that a variety of other non-traditional risk factors also influence CVD risk, including markers of central fat deposition, inflammation, nutrition, alcohol use and early growth. Given the disadvantaged circumstances of many Aboriginal people, it is likely that some of the factors are influencing their CVD risk. The applicants have collected baseline risk factor data on volunteers in one Aboriginal community and followed their course, including CVD deaths and CVD hospitalisations, for more than a decade. From this baseline information, which goes beyond traditional risk markers, and from additional measures like birthweight, and markers of inflammation and nutrition assayed in retrieved serum, we will develop a variety of models for predicting a CVD risk in this group. We will also lay plans to evaluate these tools in other Aboriginal groups. A better understanding of the causes of CVD in this population is important to influence public health policy for CVD prevention. The models will be helpful health education tools at the community level and will allow therapeutic or lifestyle intervention in individuals to be targeted at their individual risk profile.Read moreRead less
Understanding The Role Of Psychological Factors In The Etiology, Prevention And Treatment Of High Dental Fear
Funder
National Health and Medical Research Council
Funding Amount
$344,007.00
Summary
Despite dental fear being one of the most common fears experienced by Australians, the etiology of this serious condition is still not well understood and both the prevention and treatment of dental fear are not widely or effectively implemented. This project aims to better understand the psychological processes at work in determining dental fear through further research as well as by gaining first hand experience at one of only a handful of dental fear research clinics in the world.