Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmen ....Fisheries genomics of snapper in Australia and New Zealand Waters. This industry-driven project aims to assemble a strategic research alliance to generate and apply knowledge to a highly significant fisheries resource. It involves collaboration between the five major state government fisheries agencies in Australia, the New Zealand’s Crown Research Institute for seafood and two Australian labs with leadership in fish genetics and genomics. It expects to generate and integrate genomic, environmental and phenotypic datasets for snapper populations from across vast coastal regions of the two countries. The outcomes should substantially enhance intra- and inter-jurisdictional fisheries management and aquaculture initiatives, providing commercial, social and environmental benefits for many stakeholders.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE120100158
Funder
Australian Research Council
Funding Amount
$750,000.00
Summary
The Nanten2 sub-millimetre telescope. The millimetre-wavelength sky holds the key for understanding how stars form in the coldest regions of interstellar space: the molecular clouds of our Galaxy. A new frontline facility in Chile will be used in an international research endeavour to map their structures, in order to find out how they form and what causes stars to be born inside them.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE110100038
Funder
Australian Research Council
Funding Amount
$150,000.00
Summary
The NANTEN2 Observatory sub-millimetre wave telescope. The millimetre-wavelength sky holds the key to understanding how stars form in the coldest regions of interstellar space: the molecular clouds of our Galaxy. This new frontline facility in Chile will be used in an international research endeavour to map these cold regions and the stars they contain in order to find out how they form and what causes stars to be born within them.
GABA(B) Receptor Modulation Of Gastrointestinal Function In Health And Disease By Alpha-Conotoxins
Funder
National Health and Medical Research Council
Funding Amount
$689,050.00
Summary
Chronic visceral pain is a common and debilitating condition arising from numerous diseases that affect our internal organs. There is a desperate need for more information about the mechanisms responsible for signalling chronic visceral pain to provide therapies and potentially find a cure for it. Our research focuses on ?-conotoxins (small peptides from marine cone snail venom) as novel potential therapeutic agents for the treatment of chronic visceral pain.
Investigation of the fundamental roles of class Ib MHC (major histocompatibility complex) molecules in immunity. The proposed research program, using laboratory-based and synchrotron-based radiation, will provide insight into the roles of a poorly understood class of immune molecules. This will improve our understanding of the regulation of immunity, and the knowledge gained will increase Australia's international research profile.
Transcription factor nuclear residency as a driver of gene expression. Persistently active proteins can stay in the nucleus to drive cell growth and prevent cell death. This project will define how one specific active protein can remain in the nucleus and regulate gene expression through the action of unique ribonucleic acid (RNA) molecules. The results will enable persistent gene activation to be manipulated in cancer.
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE180100202
Funder
Australian Research Council
Funding Amount
$255,120.00
Summary
Three-dimensional cryo correlative light and electron microscopy facility. This project aims to establish a three-dimensional (3D) cryo-correlative light and electron microscopy facility. The facility will integrate light microscopy with high resolution cryo-electron tomography and 3D slice-and-view focused ion beam scanning electron microscopy. The open access facility should create new capabilities for Australian researchers to tag biological events and structures with fluorescence markers and ....Three-dimensional cryo correlative light and electron microscopy facility. This project aims to establish a three-dimensional (3D) cryo-correlative light and electron microscopy facility. The facility will integrate light microscopy with high resolution cryo-electron tomography and 3D slice-and-view focused ion beam scanning electron microscopy. The open access facility should create new capabilities for Australian researchers to tag biological events and structures with fluorescence markers and image them using the currently highest resolution 3D imaging techniques for biological matter. The facility expects to reveal fundamental insights into cell and structural biology, and help drive innovation in agriculture, pharmaceutics, and biomaterials.Read moreRead less
Linkage Infrastructure, Equipment And Facilities - Grant ID: LE150100011
Funder
Australian Research Council
Funding Amount
$346,439.00
Summary
Spinning disk confocal microscope with dual stages. Spinning disk confocal microscope with dual stages: This custom-built spinning disk confocal microscope with rotational stages will constitute an internationally unique platform. The system has the capability of rapidly monitoring cells in growing biological specimens under changing environments. It offers an integrated platform for multiple imaging strategies, including confocal and Total Internal Reflection Fluorescence (TIRF) microscopy. The ....Spinning disk confocal microscope with dual stages. Spinning disk confocal microscope with dual stages: This custom-built spinning disk confocal microscope with rotational stages will constitute an internationally unique platform. The system has the capability of rapidly monitoring cells in growing biological specimens under changing environments. It offers an integrated platform for multiple imaging strategies, including confocal and Total Internal Reflection Fluorescence (TIRF) microscopy. The system will reside in core facilities with open access to a broad research community. The system may be used to monitor a wide variety of cells and molecules, and will offer capabilities that are of importance to understand cell trafficking, disease and signalling, plant biomass production, and climate change.Read moreRead less