Cellular mechanisms that protect against copper-bound beta-amyloid. This project will investigate some of the brain’s own mechanisms for protecting itself against Alzheimer’s disease. Understanding these mechanisms will be important for developing future therapeutic strategies for treating Alzheimer’s disease.
ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial ....ARC Research Network in Spatially Integrated Social Science. The ARC Research Network in Spatially Integrated Social Science (SISS) builds Australia's capacity and capability for innovative, collaborative, cross-disciplinary effort to investigate the impacts of change on the behaviour and well-being of people and the fortunes of places. SISS theories and research tools permit the integration of diverse and complex databases, the generation of new synthetic datasets, the incorporation of spatial concepts into statistical analysis and modelling, powerful visualisation of information, and the building spatial decision support systems, to provide an improved evidence base and better informed decision-making to address the significant challenges facing Australia's people and its places.Read moreRead less
Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be ....Old brain cells perform new tricks to allow life-long learning. In the brain, nerve cells transmit electrical signals more quickly and reliably when they are insulated. The insulating cells undergo small adaptive changes that speed up information transfer during learning, and the faster the electrical signal, the better the learning outcomes. This project aims to understand the signals that direct insulating cells to adapt and support life-long learning. In the longer term, this knowledge may be used to: develop interventions that improve learning and educational outcomes; counteract age-related memory decline and enable longer work force participation; develop strategies to circumvent the memory loss caused by brain diseases, or improve the design of computer hardware.Read moreRead less
The drowned: cultural and political geographies. This project aims to reveal and critically analyse the geographies of drowning and the drowned. Drowning is the third most common cause of death worldwide, and a subject of universal interest that is relatively limited in specifically cultural and political geographical research, policy, and debate. The project will be significant by rectifying that gap and investigating shared concerns about drowning’s abiding, widespread, profound effects. The e ....The drowned: cultural and political geographies. This project aims to reveal and critically analyse the geographies of drowning and the drowned. Drowning is the third most common cause of death worldwide, and a subject of universal interest that is relatively limited in specifically cultural and political geographical research, policy, and debate. The project will be significant by rectifying that gap and investigating shared concerns about drowning’s abiding, widespread, profound effects. The expected outcomes will include public debate about drowning and its cultural and political reach and management generated from a book, articles, and blog. Benefits will include new fundamental knowledge and practical insights about how to rethink risks and disasters in rapidly changing environments.Read moreRead less
Analysing the protective role of platelets during malaria infection. Platelets protect the host during malarial infection. This project aims to study how platelets kill the malaria parasite by investigating the role of host molecules and their potential as novel antimalarial agents. The role of platelets in the pathogenesis of cerebral malaria syndrome will also be investigated.
Geographies of house and contents under-insurance. This project aims to analyse house and contents insurance to advance strategic disaster management. When natural disasters strike, house and contents insurance provides a safety net, but many households are under-insured or not insured at all. Governments and communities tend to bear the costs, but the geographies of inadequate insurance, including any crucial post-disaster effects, are unknown. This research is expected to strategically improve ....Geographies of house and contents under-insurance. This project aims to analyse house and contents insurance to advance strategic disaster management. When natural disasters strike, house and contents insurance provides a safety net, but many households are under-insured or not insured at all. Governments and communities tend to bear the costs, but the geographies of inadequate insurance, including any crucial post-disaster effects, are unknown. This research is expected to strategically improve disaster policy and practice, and reduce the financial and social costs of disasters to governments, communities and householders.Read moreRead less
Antarctic cities and the global commons: Rethinking the gateways. Antarctic cities and the global commons: Rethinking the gateways. This project aims to investigate how the Antarctic gateway cities of Hobart, Christchurch and Punta Arenas might reimagine and intensify their relations to the continent and each other. As pressures on Antarctica increase, five 'gateway cities'—Hobart, Cape Town, Christchurch, Punta Arenas and Ushuaia—will become critical to its future. This research is expected to ....Antarctic cities and the global commons: Rethinking the gateways. Antarctic cities and the global commons: Rethinking the gateways. This project aims to investigate how the Antarctic gateway cities of Hobart, Christchurch and Punta Arenas might reimagine and intensify their relations to the continent and each other. As pressures on Antarctica increase, five 'gateway cities'—Hobart, Cape Town, Christchurch, Punta Arenas and Ushuaia—will become critical to its future. This research is expected to create a robust custodial network of partner organisations that helps these cities care for Antarctica.Read moreRead less
Caring for thoroughbreds: addressing social, economic and welfare issues in international horse racing. Horse racing is an economically valuable industry but visible welfare issues are challenging its future. This study addresses perceptions and the economic worth of these issues internationally. Research findings about values, and alternatives to jump racing and whipping horses, will help change the conduct of horse racing around the world.
Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes wi ....Microfluidic technology to help understand physical damage to brain cells. Understanding the organisation, structure and mechanisms of the human brain and nervous system remains one of the biggest challenges of science. This project aims to develop a new cell culture platform to form defined molecular networks of brain cells and to monitor changes throughout the network in response to a small localised injury within the network. This innovative platform will be used to help understand changes within cells in response to physical damage to networks of brain cells. This is one of the major causes of death and disability in developed nations, and is identified as a risk factor for a range of neurodegenerative diseases including Alzheimer's, Parkinson's and motor neuron disease.Read moreRead less
A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These includ ....A Game Changer? Alcohol and Women's Sport in Australia. This project aims to investigate emerging relationships between women and alcohol in Australian sport. We will examine the meanings that drinking may have for sportswomen and female fans, and identify new theoretical frameworks for rethinking drinking, gender and sport. In the context of public and policy debates about the risks and social impacts of alcohol consumption, we expect to generate significant new knowledge outcomes. These include a world first research corpus of direct relevance for sports administrators and policy-makers, who are currently grappling with the costs and consequences of alcohol use in licensing and legislation, as well as in marketing, sponsorship and promotion of sport to women.Read moreRead less