The role of households, neighbourhoods and networks in social statistics. Many issues affect the social progress of the country. Social research can determine the factors affecting issues such as unemployment, poverty, educational attainment, crime victimization and poor health. Survey and other data are used extensively to examine these conditions and their association with attributes of people. This project will provide methods to better determine the impact of effects associated with the h ....The role of households, neighbourhoods and networks in social statistics. Many issues affect the social progress of the country. Social research can determine the factors affecting issues such as unemployment, poverty, educational attainment, crime victimization and poor health. Survey and other data are used extensively to examine these conditions and their association with attributes of people. This project will provide methods to better determine the impact of effects associated with the household structure and other groups and social networks. The improved ability to assess the impact of these factors will have economic and social benefits. These benefits will arise from improved analysis leading to better decisions and improvements in the design of research studies improving their cost efficiency.Read moreRead less
The HIV Prevention Revolution: Measuring Outcomes And Maximising Effectiveness
Funder
National Health and Medical Research Council
Funding Amount
$1,081,723.00
Summary
There have been extra-ordinary recent biomedical advances in HIV prevention. These present an opportunity to turn the HIV epidemic around. We will undertake implementation research to optimise the impact of the new tools at the population level. NSW has a detailed HIV strategy with explicit targets for reduction of HIV transmission over the period 2012 to 2020. Our research will guide optimum program delivery to drive new HIV infections down in Australia and other high income settings.
A Randomised Open-label Study Comparing The Safety And Efficacy Of Two Alternative Treatment Options In The Management Of HIV-1 Infected Participants Who Have Virologically Failed A Standard First-line Combination ART Regimen
Funder
National Health and Medical Research Council
Funding Amount
$457,676.00
Summary
For the past decade there has been an unprecedented international effort to provide access to care for all HIV-infected people as a basic human right. Most of these people are treated with a simple combination of drugs that are well proven to control HIV. However, what to do when this first drug combination stops working is unknown. This study aims to fill that knowledge gap so that patients failing the first drug combination can be offered a second combination with a maximal chance of success.
How do we know what works: ethics and evidence in surgical research. This project will make surgery safer for patients by improving our understanding of evidence in surgery. We will look at the question "what works" in surgery. The resources we develop will help practitioners and regulators to better navigate and manage the complex ethical and practical challenges in this field.
Poor Women and Lonely Men: Examining Gendered Social Inclusion and Connection in Australia. This project directly supports the national research priority goal of 'strengthening Australia's social and economic fabric' (as part of Promoting and Maintaining Good Health). Inclusive societies reap many benefits (economic, education, crime, health etc), and information revealed about relevant gendered patterns will help build social inclusion and connection in Australia by informing inclusive strategi ....Poor Women and Lonely Men: Examining Gendered Social Inclusion and Connection in Australia. This project directly supports the national research priority goal of 'strengthening Australia's social and economic fabric' (as part of Promoting and Maintaining Good Health). Inclusive societies reap many benefits (economic, education, crime, health etc), and information revealed about relevant gendered patterns will help build social inclusion and connection in Australia by informing inclusive strategies and policies. The project also supports the national research priority goal 'ageing well and productively', by informing policy-contexts of specific disadvantage, such as amongst those ageing alone. The project will also add to broader understandings about the links between social inclusion, connection and wellbeing.Read moreRead less
An analysis of research ethics and the ethical review process as culture and cultural process. This project explores research ethics and the ethical review process as culture and cultural process. It includes analyses of international ethics review-related documents, literature, and processes, case studies, key informant interviews, and observation of ethics committees in the process of deliberation. It focuses primarily on work associated with the paradigms and methods used or borrowed from t ....An analysis of research ethics and the ethical review process as culture and cultural process. This project explores research ethics and the ethical review process as culture and cultural process. It includes analyses of international ethics review-related documents, literature, and processes, case studies, key informant interviews, and observation of ethics committees in the process of deliberation. It focuses primarily on work associated with the paradigms and methods used or borrowed from the social sciences and topics and populations that seem to be the most problematic. This understanding might help us better address the issues involved and allow the development of policies and applications that are less problematic for all concerned.Read moreRead less
An In Depth Analysis Of Clinical And Virological Outcomes Of 2 Strategies For The Antiretroviral Salvage Of First-line Regimen Virological Failure For HIV-1 Infection Tested In An Australian-led Randomised, International, Multi-centre Clinical Trial
Funder
National Health and Medical Research Council
Funding Amount
$421,747.00
Summary
The recently completed Australian-led SECOND-LINE trial is the first high quality study to provide reliable evidence for policy recommendations for the composition of anti-HIV drug cocktails after standard initial treatment has failed. This award will support the researcher in further refining our understanding of how to manage second-line therapy including proposals to test the use of low-cost technologies for application in resource-limited settings where the majority of people with HIV live.
Understanding civil society activists. The growing role and importance of civil society groups demands an understanding of their philosophical and intellectual underpinnings and who the people are that support their agendas. This project provides a multifaceted picture of the supporters of three critical social causes: environmental sustainability, animal welfare and economic globalisation. Understanding who these people are and what motivates them will give us a better understanding of many o ....Understanding civil society activists. The growing role and importance of civil society groups demands an understanding of their philosophical and intellectual underpinnings and who the people are that support their agendas. This project provides a multifaceted picture of the supporters of three critical social causes: environmental sustainability, animal welfare and economic globalisation. Understanding who these people are and what motivates them will give us a better understanding of many of the drivers of our own economic and social future, thereby helping to strengthen Australia's social and economic fabric.Read moreRead less
Mapping the Frontiers of Private Property in Australia. This project aims to develop a new DH dataset, systematically documenting and mapping the first generation of Australian private property ownership. The project expects to generate new knowledge of this phenomenon in New South Wales from 1788 onwards, using historical records to develop a digital map that shows where, when and to what extent parcels of land in NSW moved from Crown ownership into private hands. Expected outcomes include an o ....Mapping the Frontiers of Private Property in Australia. This project aims to develop a new DH dataset, systematically documenting and mapping the first generation of Australian private property ownership. The project expects to generate new knowledge of this phenomenon in New South Wales from 1788 onwards, using historical records to develop a digital map that shows where, when and to what extent parcels of land in NSW moved from Crown ownership into private hands. Expected outcomes include an open access map that will for the first time enable scholars to place the history of property ownership into conversation with other aspects of Australian history. Among its benefits it will enable future scholarly work and citizen engagement to effectively extend knowledge of Australia's property history.Read moreRead less
Creating Sustainable Healthcare: Ensuring New Diagnostics Avoid Harms, Improve Outcomes, And Direct Resources Wisely
Funder
National Health and Medical Research Council
Funding Amount
$2,497,658.00
Summary
Novel imaging, biomarkers and genomic tests for risk assessment and early detection are emerging as major forces for change in clinical practice. While providing advances and new benefits for patients, new technologies can also have harmful, unintended consequences - overdiagnosis and overtreatment. This multidisciplinary CRE will investigate how to respond to emerging technologies to optimise health outcomes while avoiding harms and directing healthcare resources wisely.