Enhanced Control Of Hypertension And Thrombolysis In Stroke Study (STAY ENCHANTED)
Funder
National Health and Medical Research Council
Funding Amount
$2,437,384.00
Summary
"Clot busting" treatment is the only approved medical treatment for the commonest type of stroke, ischaemic stroke. However, uptake of treatment remains poor, mainly due to the known major risk of bleeding in the brain. STAY ENCHANTED is an international clinical trial to investigate whether "clot-busting" can be made safer using a lower dose and/or immediate blood pressure lowering. A safer more effective regime could have a major global health impact.
Schistosomiasis is a major public health problem in the Philippines with approximately 6.7 million people at risk of infection. Mass human chemotherapy has formed the cornerstone of control for decades but has failed to control the disease. Transmission reduction is a key step towards elimination and integrated interventions should target both definitive and intermediate host transmission pathways. We propose to trial integrated control strategies for the disease and expect the outcomes to have ....Schistosomiasis is a major public health problem in the Philippines with approximately 6.7 million people at risk of infection. Mass human chemotherapy has formed the cornerstone of control for decades but has failed to control the disease. Transmission reduction is a key step towards elimination and integrated interventions should target both definitive and intermediate host transmission pathways. We propose to trial integrated control strategies for the disease and expect the outcomes to have broader implications for Southeast Asia.Read moreRead less
Rates, Patterns And Determinants Of Alcohol’s Harm To Others: A Cross-national Comparative Study
Funder
National Health and Medical Research Council
Funding Amount
$305,856.00
Summary
Alcohol causes harms to drinkers, and others around them, including spouses, children, family, friends, workmates and strangers. Australian and New Zealand work on alcohol’s harm to others is being replicated by the WHO in 7 countries (Chile, Nigeria, Sri Lanka, India, Thailand, Laos and Vietnam). We aim to analyse datasets from nine countries and compare the magnitude and patterning of problems across and within cultures – identifying opportunities for reducing harm from others’ drinking.
Combining Health, Laboratory And Immunisation Data Sources To Identify Opportunities For The Prevention Of Chest Infections In Young Aboriginal And Non-Aboriginal Children
Funder
National Health and Medical Research Council
Funding Amount
$428,469.00
Summary
Chest infections are one of the major reasons children are admitted to hospital, particularly in Aboriginal children. This project will determine whether current vaccines have reduced hospital visits and how many children are affected by multiple infections. It will also identify where better vaccination programs are needed. This will be done by bringing together and analysing a range of infection and hospital records to paint a true picture of the impact of chest infections in children.
A National Population-based Study Of Rheumatic Heart Disease In Pregnancy
Funder
National Health and Medical Research Council
Funding Amount
$877,826.00
Summary
Whilst overall a rare disease, Indigenous peoples have disproportionately high rates of rheumatic heart disease (RHD). This study explores the prevalence and distribution of RHD in pregnancy in Australia and New Zealand. It details current management, diagnostic and referral process and risk factors. Key attributes of culturally safe models of care for RHD in pregnancy are explored, particularly as they relate to Indigenous women. Findings will inform policy, guidelines and education resources.
Detection Of Liver And Renal Function Abnormalities In The Australian & New Zealand Population Of Fontan Patients
Funder
National Health and Medical Research Council
Funding Amount
$345,080.00
Summary
Children born with complex heart defects and only one pumping chamber can now live into adulthood with an operation called the Fontan procedure. As this operation has only existed for 40 years, the long-term expectations for these children and young adults are still unclear, and their population is growing every year. There is now evidence that they may suffer from liver and kidney failure. This project will identify the severity of liver and kidney damage in our population of Fontan patients.
Preventing Early Academic Problems By Improving Working Memory: Translational Randomised Trial
Funder
National Health and Medical Research Council
Funding Amount
$831,085.00
Summary
Learning difficulties are common and can cause school failure and poor self-esteem. They are associated with specific problems with temporarily remembering and using information (‘working memory’). Research suggests that improving working memory might improve academic achievement. We will study this intervention in a large group of primary school children who have poor working memory. If successful, the intervention will provide a way to improve the learning skills of these high-risk children.