A Cluster RCT Of The Impact Of A Community-based Hygiene And Sanitation Programme On Infection With Intestinal Parasites Following Mass Albendazole Chemotherapy In Timor-Leste
Funder
National Health and Medical Research Council
Funding Amount
$1,178,136.00
Summary
Intestinal parasites cause anaemia, stunting, wasting and poor mental development in childhood, and are related to poverty and poor hygiene. Treatment with antiparasitic drugs cures infections in human hosts, but does not prevent rapid re-infection when people contact a parasite-contaminated environment. We will quantify the impact of a hygiene and sanitation programme that reduces environmental contamination in communities that receive mass treatment with the antiparasitic drug albendazole.
A New Genomic Frontier For Foodborne Disease Investigation In Australia
Funder
National Health and Medical Research Council
Funding Amount
$750,520.00
Summary
Foodborne diseases caused by bacteria such as Salmonella and Campylobacter are a huge public health problem, both in Australia and globally. Current methods used to investigate foodborne disease may not be sensitive enough to track foodborne outbreaks, and may not even detect them in the first place. We propose using cutting-edge molecular techniques to investigate foodborne outbreaks, and we think that using these methods will enable outbreaks to be interrupted at a much earlier stage.
New Technologies To Reduce The Population Burden Of Sexually Transmitted Infections
Funder
National Health and Medical Research Council
Funding Amount
$772,605.00
Summary
I propose a five year program of public health research on the evaluation of innovative technologies to prevent sexually transmitted infections (STIs) and their adverse consequences in populations at highest risk; Aboriginal and Torres Strait Islander people, youth, men who have sex with men and people in high STI-burden resource-limited countries. My research over the next five years will lead to substantial improvements in the health of people at greatest risk of STIs.
Evaluating The Uptake And Impact Of The HIV/STI Prevention And Treatment Revolution
Funder
National Health and Medical Research Council
Funding Amount
$435,411.00
Summary
The aims of this ECF are to: a) assess the uptake and impact of new HIV prevention options; b) evaluate the effectiveness of antibiotic treatment for bacterial STIs; and c) determine risk factors of ill health caused by STIs. State-of-the-art methods will be applied for the design and analysis of various types of studies. All research will inform HIV/STI policy, prevention programs, and clinical practice – in Australia and abroad. Findings will be disseminated widely e.g. to policy makers.
Clostridium Difficile: Assessing The Risks To Australia Of An Emerging Healthcare-related Pathogen
Funder
National Health and Medical Research Council
Funding Amount
$1,180,256.00
Summary
Clostridium difficile is a bacterium that causes inflammation of the large bowel that can lead to surgical removal of the bowel or death. In North America and Europe, an international epidemic strain has caused large outbreaks of severe, fatal disease. In 2009, this strain was identified for the first time in Perth, Australia. We will investigate strains currently present in Brisbane and Perth and risk of outbreaks occurring from imported and local strains.
Rapid Point-of-Care (POC) Tests For Sexually Transmitted Infections (STIs): Evaluation Of Accuracy, Acceptability And Impact In Australia And Papua New Guinea (PNG)
Funder
National Health and Medical Research Council
Funding Amount
$99,883.00
Summary
This research, composed of three studies, aims to evaluate rapid point-of-care tests for selected sexually transmitted infections (including syphilis, Chlamydia and gonorrhoea) to determine their accuracy and acceptability, their potential role in and impact on control of STIs in Papua New Guinea and remote settings in Australia.
Use Of Statistical And Mathematical Models To Investigate Infectious Disease Transmission Dynamics To Better Inform Control Measures In Hospitals And The Community
Funder
National Health and Medical Research Council
Funding Amount
$408,388.00
Summary
Globally tuberculosis infects over 9 million people yearly. In low incidence countries TB is re-emerging, with HIV, drug resistance and migration driving this. Australia needs to examine the transmission of TB within our country and The Asia-Pacific region. This proposal will quantify the risk for importation of highly drug resistant TB into Australia and assess the factors that lead to outbreaks. Models will be informative for Australian TB policy development and contribute to regional and glob ....Globally tuberculosis infects over 9 million people yearly. In low incidence countries TB is re-emerging, with HIV, drug resistance and migration driving this. Australia needs to examine the transmission of TB within our country and The Asia-Pacific region. This proposal will quantify the risk for importation of highly drug resistant TB into Australia and assess the factors that lead to outbreaks. Models will be informative for Australian TB policy development and contribute to regional and global efforts for TB control.Read moreRead less
Viral Load, HIV Treatment, And HIV Transmission In Serodiscordant Male Homosexual Couples
Funder
National Health and Medical Research Council
Funding Amount
$1,452,298.00
Summary
HIV treatment reduces the concentration of HIV in the body. In heterosexuals, current studies will determine the effectiveness of HIV treatment in preventing onwards HIV transmission. In contrast, there has been very little such research in homosexual men, who comprise 70% or more of people with HIV in Australia. This study will follow for four years over 200 male homosexual couples in which one is HIV positive and the other negative, to investigate the role of HIV treatment in HIV prevention.