Does Environmental Change Drive The Spatiotemporal Transmission Dynamics Of Echinococcus Spp. In Ningxia, China?
Funder
National Health and Medical Research Council
Funding Amount
$654,548.00
Summary
Human echinococcosis is a chronic debilitating disease with a death rate that can exceed 90%. In China it is a major public health issue where recent environmental changes are likely to increase transmission rates, thus increasing the disease burden. This project will assess the impact of these environmental changes on the transmission of this disease over space and time, it will predict where new cases will arise, and determine the best methods for sustainable control and then elimination.
Using An Established Simulation Model To Determine Effective And Cost-effective Interventions To Mitigate Influenza Pandemics And Inform Public Health Policy
Funder
National Health and Medical Research Council
Funding Amount
$416,353.00
Summary
A novel disease spread and economic model is used to determine the cost-effectiveness of a range of mitigation strategies aimed at a future influenza pandemic. A simulation model generates data on which individuals become ill, morbidity and mortality characteristics, an economic costing model determines optimal interventions.
Heritable And Environmental Determinants Of Hospitalisation For Common Childhood Illnesses
Funder
National Health and Medical Research Council
Funding Amount
$468,238.00
Summary
This study will combine the unique and powerful resources of the Western Australian (WA) Data Linkage System and the WA Twin Register to disentangle the effects of genetics and the environment on the most common infectious causes of hospital admissions in children. It will highlight appropriate pathways to prevent such admissions in the future.
Investigation Of Candidate Aetiologic Organisms Of Bacterial Vaginosis In Diverse And Unique Epidemiological And Clinical Studies
Funder
National Health and Medical Research Council
Funding Amount
$564,438.00
Summary
Bacterial vaginosis (BV), a vaginal infection affecting 10% of Australian women, is an important cause of premature birth, yet its cause is unknown. We are conducting studies to understand the cause of BV in order to improve diagnosis and treatment.
Graves’ disease is the most common cause of hyperthyroidism. It leads to long-term impairments in quality of life and has a 40% higher mortality rate compared with the general population. We know surprisingly little about the causes of Graves’ disease. One possible trigger is stressful life events; however, the relationship is yet to be proven. This study will assess whether stressful life events, specifically military deployment, are associated with Graves’ disease.
AusDiab 3: Emerging Risk Factors For And Long-term Incidence Of Cardio-metabolic Diseases
Funder
National Health and Medical Research Council
Funding Amount
$2,616,397.00
Summary
This study will track 11,000 Australian adults over 12 years to determine how many develop diabetes, obesity, kidney and heart disease. The study will develop ways to best predict those who are going to develop these conditions before they have arisen, and will explore a range of novel risk factors to better understand these conditions.
What Are The Clinical Predictors And Risk Factors For Impaired Child Growth And Development? Following Up The Ha Nam Cohort From Birth To 3 Years
Funder
National Health and Medical Research Council
Funding Amount
$1,189,570.00
Summary
Stunting affects about one third of children under five in developing countries and is a measure of chronic undernutrition. This project will identify pre and postnatal risk factors for impaired child growth and development by monitoring a cohort of infants in Vietnam to three years of age, and developing a predictive algorithm for early detection of those at risk of stunting. Effective preventative measures would improve child health, and prevent a huge burden of disease.
Preventing Mortality In Adults After Release From Prison: Advancing Global Knowledge Through An International, Individual Participant Data Meta-analysis
Funder
National Health and Medical Research Council
Funding Amount
$613,687.00
Summary
Ex-prisoners are at increased risk of death, but not enough is known about the incidence, timing, causes, context or risk factors for preventable death in this population. In this project we have compiled 18 cohorts of ex-prisoners (total number=1,159,290) and will analyse the data to determine exactly which ex-prisoners are at the greatest risk from what, and when. This new knowledge will inform policy changes to reduce the unnecessary loss of life in this vulnerable population.
InterLACE: International Collaboration For A Life Course Approach To Reproductive Health And Chronic Disease Events
Funder
National Health and Medical Research Council
Funding Amount
$495,965.00
Summary
Cardiovascular disease and diabetes are major chronic diseases among women. This world-leading research combines data from 7 international and 3 Australian studies of womenÍs health. We will investigate the relationship of reproductive health, from menarche to menopause, with the risk of Type 2 diabetes and cardiovascular disease in later life. Findings will support the development of policies and preventive health strategies to reduce the risk of these chronic diseases.
Evaluation Of Long-Term Clinical And Health Service Outcomes Following Coronary Artery Revascularisation In Western Australia: Future Implications
Funder
National Health and Medical Research Council
Funding Amount
$638,412.00
Summary
Heart attacks occur when arteries of the heart become blocked, and current treatment involves unblocking the affected vessel by inserting a stent fed through a leg artery or using bypass surgery. There are different types of stents and whether they offer better outcomes than surgery in the long-term is currently undecided. We will evaluate whether patients who receive stents have better outcomes after 5 years than patients who have surgery, and what the various costs are to the health system.