Biological applications of terahertz technology. This project aims to develop new knowledge for exploring the interaction of terahertz (THz) radiation with different materials. THz technology is in use in diverse applications from security screening to biomedical imaging. A hurdle to the widespread adoption of the technology is the poor understanding of the basic interaction between THz radiation and molecules, proteins, cells and tissues. This project will enable development of advanced THz tec ....Biological applications of terahertz technology. This project aims to develop new knowledge for exploring the interaction of terahertz (THz) radiation with different materials. THz technology is in use in diverse applications from security screening to biomedical imaging. A hurdle to the widespread adoption of the technology is the poor understanding of the basic interaction between THz radiation and molecules, proteins, cells and tissues. This project will enable development of advanced THz technology and applications and will lead to accelerated implementation for use in chemistry, biology and, ultimately, medicalapplications such as cancer detection.Read moreRead less
Theoretical modelling of the interaction of THz with hydrated materials. Terahertz (THz) technology is in use in diverse applications from security screening to biomedical imaging. A critical hurdle to the widespread adoption of the technology is the poor understanding of the basic interaction between THz radiation and hydrated materials. The aim of this project is to develop new mathematical and computer models for exploring the interaction of THz radiation with different materials. These model ....Theoretical modelling of the interaction of THz with hydrated materials. Terahertz (THz) technology is in use in diverse applications from security screening to biomedical imaging. A critical hurdle to the widespread adoption of the technology is the poor understanding of the basic interaction between THz radiation and hydrated materials. The aim of this project is to develop new mathematical and computer models for exploring the interaction of THz radiation with different materials. These models aim to create a platform for the future development of THz technology and applications, and are expected to lead to accelerated implementation for use in biology and protein analysis; pharmaceutical sciences, formulations and medicine; and burn assessment and cancer detection.Read moreRead less
Interrogating protein hydration by terahertz time-domain spectroscopy. Interrogating protein hydration by terahertz time-domain spectroscopy. This project aims to develop advanced terahertz time-domain spectroscopy (THz-TDS) techniques to understand how a protein’s interaction with excipients in solution can alter the hydration layers around them and how this affects properties such as viscosity and stability. THz-TDS can detect overlapping extended hydration layers around proteins, revealing ne ....Interrogating protein hydration by terahertz time-domain spectroscopy. Interrogating protein hydration by terahertz time-domain spectroscopy. This project aims to develop advanced terahertz time-domain spectroscopy (THz-TDS) techniques to understand how a protein’s interaction with excipients in solution can alter the hydration layers around them and how this affects properties such as viscosity and stability. THz-TDS can detect overlapping extended hydration layers around proteins, revealing new knowledge in protein-protein interactions and protein behaviour in an aqueous environment. The intended outcome is to use THz-TDS to better understand how proteins such as monoclonal antibodies interact in high concentration solutions, and in doing so make better medicines.Read moreRead less