Transforming The Diagnosis And Management Of Severe Neurocognitive Disorders Through Genomics
Funder
National Health and Medical Research Council
Funding Amount
$2,499,330.00
Summary
Neurocognitive disorders (NCD) are one of the most common genetic conditions in our society and it results with a need for ongoing permanent care for many affected people. Until recently, only 30% of people with NCD could be diagnosed but this has changed with the availability of genomic testing where all genes can be tested at once. The use of genomics in the CRE will lead to new NCD genes being identified and this information being translated into a clinical setting.
Regional resilience to economic shocks: Australia’s COVID Economic slowdown. This project is designed to analyse how employment outcomes in Australian regions respond to economic shocks such as that caused by COVID-19. Set within the emerging literature dealing with employment resilience, the project uses unique data (Payroll Jobs index) to measure employment resilience and understand the factors that impact diverse regional outcomes. Understanding these patterns is significant as a region's ec ....Regional resilience to economic shocks: Australia’s COVID Economic slowdown. This project is designed to analyse how employment outcomes in Australian regions respond to economic shocks such as that caused by COVID-19. Set within the emerging literature dealing with employment resilience, the project uses unique data (Payroll Jobs index) to measure employment resilience and understand the factors that impact diverse regional outcomes. Understanding these patterns is significant as a region's economic performance has the potential to impact the well being of individuals and their families, as well as the sustainability of local economies and communities. The project will result in a nuanced understanding of regional employment performance that will inform policy in both government and non-government sectors. Read moreRead less
Evolutionary Dynamics and the Transformation of Rural Australia. Understanding the ways in which Australia's rural heartland has been transformed is critical to constructing competitive regions. This project aims to pioneer the application and development of evolutionary economic geography and staples theory to an investigation of the transformation of south-east and south-western Australia, covering the long boom of the post-war period, through the restructuring 'crisis' of the 1980s and 1990s, ....Evolutionary Dynamics and the Transformation of Rural Australia. Understanding the ways in which Australia's rural heartland has been transformed is critical to constructing competitive regions. This project aims to pioneer the application and development of evolutionary economic geography and staples theory to an investigation of the transformation of south-east and south-western Australia, covering the long boom of the post-war period, through the restructuring 'crisis' of the 1980s and 1990s, to a multifunctional countryside. The explanatory power of the local modelling 'tools' that this project is expected to develop moves beyond the 'one size fits all' suite of policy prescriptions, with the specific potential to inform rural and regional policy and practice.Read moreRead less
Does Caffeine Affect The Development Of The Very Immature Brain: Dose Response Relationship?
Funder
National Health and Medical Research Council
Funding Amount
$668,386.00
Summary
Premature birth is a major health problem worldwide. Preterm babies often develop apnoea of prematurity (AOP), which is commonly treated with caffeine. Trials indicate that preterm babies treated with low dose caffeine have less neurodevelopmental disabilities at 18 months. Higher doses of caffeine are often needed to reduce AOP but the risk of this is unknown. We will study the short and long-term effects of increasing doses of caffeine on the developing brain in a long-gestation species.
The Demand for Higher Density Housing in Sydney and Melbourne. The research will support the development of more socially sustainable approaches to the planning of higher density housing in Australian cities. The project will improve our understanding of the processes driving higher density urban change (and therefore the risks of such development), inform better land use outcomes, assist in reducing potential community conflict over development proposals, and enhance wider social sustainabilit ....The Demand for Higher Density Housing in Sydney and Melbourne. The research will support the development of more socially sustainable approaches to the planning of higher density housing in Australian cities. The project will improve our understanding of the processes driving higher density urban change (and therefore the risks of such development), inform better land use outcomes, assist in reducing potential community conflict over development proposals, and enhance wider social sustainability of urban areas, thereby strengthening the social fabric of Australian cities. The research will also add to academic debates surrounding the benefits (or non-benefits) of building higher density cities and on the structure of spatially segmented urban housing markets. Read moreRead less
Implementing metropolitan planning strategies: taking into account local level housing demand. This project will make a major contribution to our knowledge of contemporary urban change and will inform wider debates on the future of Australian cities. Providing planners and community stakeholders with a better understanding of housing demand at a local level, the research will assist in the implementation of metropolitan planning strategies, offering an effective framework that can incorporate af ....Implementing metropolitan planning strategies: taking into account local level housing demand. This project will make a major contribution to our knowledge of contemporary urban change and will inform wider debates on the future of Australian cities. Providing planners and community stakeholders with a better understanding of housing demand at a local level, the research will assist in the implementation of metropolitan planning strategies, offering an effective framework that can incorporate affordability and social inclusion considerations. The research relates directly to the National Housing Supply Council's emerging agenda, which has identified the need to consider housing demand across a variety of spatial scales, and responds to the priority goal of strengthening Australia's social and economic fabric.Read moreRead less
The Drivers and Outcomes of Re-investment in Low Density Suburban Housing Markets. This project will make a major contribution to our knowledge of contemporary Australian urban change and will inform wider debates on the future of Australian cities. The project will explore the social and economic processed leading to reinvestment and renewal of older low density suburban housing and will offer insights into community-level attitudes to housing built to higher environmental standards. This proj ....The Drivers and Outcomes of Re-investment in Low Density Suburban Housing Markets. This project will make a major contribution to our knowledge of contemporary Australian urban change and will inform wider debates on the future of Australian cities. The project will explore the social and economic processed leading to reinvestment and renewal of older low density suburban housing and will offer insights into community-level attitudes to housing built to higher environmental standards. This project will inform local and metropolitan planning processes related to sustainable suburban renewal and support policies that reduce community concerns and uncertainty over change, thereby contributing to the strengthening of the social fabric of our cities.Read moreRead less
Achieving urban vitality: skills & employment development in shrinking cities. The study will provide a conceptual framework for understanding the dynamics of shrinking cities, its typology, and the trajectories of these cities in Australia, Europe, USA and Japan. The study questions traditional paradigms of growth and decline and demographic change.
At a policy and strategic level, the project will provide a review and assessment of policies, programs and regeneration strategies in areas in de ....Achieving urban vitality: skills & employment development in shrinking cities. The study will provide a conceptual framework for understanding the dynamics of shrinking cities, its typology, and the trajectories of these cities in Australia, Europe, USA and Japan. The study questions traditional paradigms of growth and decline and demographic change.
At a policy and strategic level, the project will provide a review and assessment of policies, programs and regeneration strategies in areas in decline in Australia as well as a database of best practices in terms of skills and employment programs in shrinking cities as per the typology developed in the study. The study will provide an international environment for research students to participate in a highly innovative transnational debate.
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Australia's Rural Heartlands: Declining Economic Fortune or Dynamic Regional Adjustment? Agriculture in the rural heartlands provides high quality food and fibre for domestic consumption and export making significant contributions to national earnings. The heartlands are the custodians of our natural resources and cultural heritage and farmers play a vital economic and social role in the sustainability of these regions. While there is considerable variability between these places this research ....Australia's Rural Heartlands: Declining Economic Fortune or Dynamic Regional Adjustment? Agriculture in the rural heartlands provides high quality food and fibre for domestic consumption and export making significant contributions to national earnings. The heartlands are the custodians of our natural resources and cultural heritage and farmers play a vital economic and social role in the sustainability of these regions. While there is considerable variability between these places this research will provide a detailed understanding as to why it is that rural places differ in their development. A major benefit will be to present Australian governments, the agricultural industry and rural communities with a more accurate picture of how the rural heartlands now function, and to articulate the public policy implications.Read moreRead less
The role of investor landlords in restructuring Australia's major cities. With their property acquisition activity reaching record levels, investor landlords are now key players in Australia's housing market. This has sparked vigorous public debate on the contribution of this activity to a 'housing price bubble' and the crowding out of first home buyers. Given new research indicating private rental provision growing fastest in the most disadvantaged neighbourhoods, another effect may be to exace ....The role of investor landlords in restructuring Australia's major cities. With their property acquisition activity reaching record levels, investor landlords are now key players in Australia's housing market. This has sparked vigorous public debate on the contribution of this activity to a 'housing price bubble' and the crowding out of first home buyers. Given new research indicating private rental provision growing fastest in the most disadvantaged neighbourhoods, another effect may be to exacerbate the socio-spatial polarisation of our major cities. This project will therefore investigate the drivers and consequences of growing private rental investment in Australia's major cities, especially in disadvantaged areas. Project findings are expected to inform national housing, planning and urban policy.Read moreRead less